Allele Dmel\lqf^bE25

General Information
Symbol	Dmel\lqf^bE25	Species	D. melanogaster
Name		FlyBase ID	FBal0066108
Feature type	allele	Associated gene	Dmel\lqf

Allele class
Mutagen	ethyl methanesulfonate
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	ethyl methanesulfonate (Fischer et al., 1997, Cadavid et al., 2000)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| recessive (Cadavid et al., 2000, Fischer et al., 1997) visible (Fischer et al., 1997)
Phenotype Manifest In
	cardioblast \| supernumerary (Tian et al., 2004) retina (Fischer et al., 1997)
Detailed Description
	Statement Reference Homozygous embryos have an excess of cardioblasts. (Tian et al., 2004) Homozygotes exhibit rough eyes, retinal morphology is extremely disrupted. (Fischer et al., 1997)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement Reference faf^BX3, lqf^bE25 has visible \| recessive phenotype, enhanceable by Chc[+]/Chc¹ (Cadavid et al., 2000) faf^BX3, lqf^bE25 has visible \| recessive phenotype, enhanceable by Chc[+]/Chc⁴ (Cadavid et al., 2000) faf^BX3, lqf^bE25 has visible phenotype, enhanceable by Chc[+]/Chc¹ (Cadavid et al., 2000) faf^BX3, lqf^bE25 has visible phenotype, enhanceable by Chc[+]/Chc⁴ (Cadavid et al., 2000)
Suppressed by
Statement Reference faf^FO8/faf^BX3, lqf^bE25 has visible \| recessive phenotype, suppressible by eff⁰¹⁴⁶² (Cadavid et al., 2000) faf^FO8/faf^BX3, lqf^bE25 has visible \| recessive phenotype, suppressible by eff^XS347 (Cadavid et al., 2000) faf^FO8/faf^BX3, lqf^bE25 has visible \| recessive phenotype, suppressible by Prosβ6¹ (Cadavid et al., 2000) faf^FO8/faf^BX3, lqf^bE25 has visible \| recessive phenotype, suppressible by Prosβ6^rv10e (Cadavid et al., 2000) faf^FO8/faf^BX3, lqf^bE25 has visible phenotype, suppressible by eff⁰¹⁴⁶² (Cadavid et al., 2000) faf^FO8/faf^BX3, lqf^bE25 has visible phenotype, suppressible by eff^XS347 (Cadavid et al., 2000) faf^FO8/faf^BX3, lqf^bE25 has visible phenotype, suppressible by Prosβ6¹ (Cadavid et al., 2000) faf^FO8/faf^BX3, lqf^bE25 has visible phenotype, suppressible by Prosβ6^rv10e (Cadavid et al., 2000)
Other
Statement Reference faf^BX3, lqf^bE25 has visible \| recessive phenotype (Cadavid et al., 2000) faf^BX3, lqf^bE25 has visible phenotype (Cadavid et al., 2000)
Phenotype Manifest In
Enhanced by
Statement Reference faf^BX3, lqf^bE25 has eye phenotype, enhanceable by Chc[+]/Chc¹ (Cadavid et al., 2000) faf^BX3, lqf^bE25 has eye phenotype, enhanceable by Chc[+]/Chc⁴ (Cadavid et al., 2000) faf^BX3, lqf^bE25 has wing phenotype, enhanceable by Chc[+]/Chc¹ (Cadavid et al., 2000) faf^BX3, lqf^bE25 has wing phenotype, enhanceable by Chc[+]/Chc⁴ (Cadavid et al., 2000)
Suppressed by
Statement Reference faf^FO8/faf^BX3, lqf^bE25 has ommatidium phenotype, suppressible by eff⁰¹⁴⁶² (Cadavid et al., 2000) faf^FO8/faf^BX3, lqf^bE25 has ommatidium phenotype, suppressible by eff^XS347 (Cadavid et al., 2000) faf^FO8/faf^BX3, lqf^bE25 has ommatidium phenotype, suppressible by Prosβ6¹ (Cadavid et al., 2000) faf^FO8/faf^BX3, lqf^bE25 has ommatidium phenotype, suppressible by Prosβ6^rv10e (Cadavid et al., 2000)
Enhancer of
Statement Reference lqf^bE25 is an enhancer of phenotype of faf^BX3 (Fischer et al., 1997)
Other
Statement Reference faf^BX3, lqf^bE25 has eye photoreceptor cell \| ectopic phenotype (Cadavid et al., 2000) faf^BX3, lqf^bE25 has ommatidium phenotype (Cadavid et al., 2000) faf^BX3, lqf^bE25 has wing phenotype (Cadavid et al., 2000)
Additional Comments
Genetic Interactions
Statement Reference Nearly all facets of lqf^bE25 faf^BX3/faf^BX3 eyes contain one or more ectopic photoreceptors in addition to the normal complement of 8. The lqf^bE25 faf^BX3/faf^BX3 mutant phenotype is dominantly enhanced by Chc¹ or Chc⁴. The lqf^bE25 faf^BX3/faf^FO8 mutant phenotype is suppressed by eff^XS347, eff⁰¹⁴⁶², Pros26^rv10e or Pros26¹. (Cadavid et al., 2000) Enhances the faf^BX3 eye phenotype: eye is malformed with a rough exterior. (Fischer et al., 1997)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	Allelic series of phenotypic severity: lqf^ARI >= lqf^AG > lqf^bE25 > lqf^bE248 > lqf^S011027. (Tian et al., 2004)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	E(faf)bE25^bE25 (Fischer et al., 1997, ) lqf^be25 (Tian et al., 2004) lqf^bE25
Name Synonym
Secondary FlyBase IDs

References ( 3 )
Research paper	Tian et al., 2004, Development 131(23): 5807--5815 Epsin potentiates Notch pathway activity in Drosophila and C. elegans. [FBrf0180177] Cadavid et al., 2000, Development 127(8): 1727--1736 The function of the Drosophila fat facets deubiquitinating enzyme in limiting photoreceptor cell number is intimately associated with endocytosis. [FBrf0127031] Fischer et al., 1997, Dev. Genet. 21(2): 167--174 Mutagenesis screens for interacting genes reveal three roles for fat facets during Drosophila eye development. [FBrf0098784]

Allele Dmel\lqfbE25

Allele Dmel\lqf^bE25