FB2025_01 , released February 20, 2025
Allele: Dmel\ushUAS.cCa
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General Information
Symbol
Dmel\ushUAS.cCa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Cubadda
FlyBase ID
FBal0082100
Feature type
allele
Associated gene
Dmel\ush
Associated Insertion(s)
Carried in Construct
P{UAS-ush.C}
Also Known As
UAS-ush
Key Links
Transgenic product class
cDNA
(Cubadda et al., 1997)
wild_type
(Cubadda et al., 1997)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Cubadda et al., 1997)
wild_type
(Cubadda et al., 1997)
Mutagen
in vitro construct
(Cubadda et al., 1997, Haenlin et al., 1997)
Progenitor genotype
Carried in construct
P{UAS-ush.C}
Cytology
Description

ush cDNA is expressed under the control of a UASt regulatory sequences.

(Cubadda et al., 1997)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
ush
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Cells in the fat body expressing ushScer\UAS.cCa under the control of Scer\GAL4Act are smaller in size than neighbouring wild-type cells.

      (Hyun et al., 2009)

      ushScer\UAS.cCa; Scer\GAL4lz-gal4 embryos have slightly reduced numbers of crystal cells at stage 13-16.

      (Waltzer et al., 2002)

      Overexpression of ushScer\UAS.cCa using Scer\GAL4pnr-MD237 results in the loss of dorsocentral precursor cells and the subsequent loss of dorsocentral bristles.

      (Cubadda et al., 1997)

      Overexpression of ushScer\UAS.cCa using Scer\GAL4pnr-MD237 leads to a loss of dorsocentral bristles.

      (Haenlin et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Ubiquitous expression of araScer\UAS.cGa under the control of Scer\GAL4unspecified abolishes photoreceptor differentiation, which is not restored by overexpression of ushScer\UAS.cCa.

      (Maurel-Zaffran and Treisman, 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      ushUAS.cCa, Scer\GAL4twi.PG, Scer\GAL4how-24B partially rescues Df(2L)ushrev18

      (Klinedinst and Bodmer, 2003)
      Comments

      When ushScer\UAS.cCa is driven by Scer\GAL4how-24B and Scer\GAL4twi.PG in Df(2L)ushrev18 embryos, 52% of embryos show a cardiac-specific tin expression that is restored close to wild-type levels.

      (Klinedinst and Bodmer, 2003)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      ushScer\UAS.cCa
      ushUAS.cCa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Cubadda
      (Cubadda et al., 1997)
      Secondary FlyBase IDs
        References (11)