Allele Dmel\flam^OR

General Information
Symbol	Dmel\flam^OR	Species	D. melanogaster
Name		FlyBase ID	FBal0082930
Feature type	allele	Associated gene	Dmel\flam
Also Known As	flam^OR(P)

Allele class
Mutagen	spontaneous
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	spontaneous (Pelisson et al., 1997)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	female fertile (Mevel-Ninio et al., 2007)
Phenotype Manifest In

Detailed Description
	Statement Reference flam^OR females have no defects in the ovaries. (Mevel-Ninio et al., 2007) Mutation can decrease the effect of flam^su(f) and flam^vg on gypsy mobilisation. (Pelisson et al., 1997)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference DIP1^t8 does not rescue the flam^OR/Df(1)l11 permissive phenotype. (Robert et al., 2001)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	Permissive mutation. (Pelisson et al., 1997)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	flam^OR(P) (Sarot et al., 2004, Robert et al., 2001, Chalvet et al., 1999) flam^OR flam^wOR(P) (Pelisson et al., 2007) OR(P) (Mejlumian et al., 2002) wOR(P) (Mevel-Ninio et al., 2007)
Name Synonym
Secondary FlyBase IDs

References ( 8 )
Research paper	Sienski et al., 2012, Cell 151(5): 964--980 Transcriptional silencing of transposons by piwi and maelstrom and its impact on chromatin state and gene expression. [FBrf0220033] Mevel-Ninio et al., 2007, Genetics 175(4): 1615--1624 The flamenco locus controls the gypsy and ZAM retroviruses and is required for Drosophila oogenesis. [FBrf0200369] Pelisson et al., 2007, J. Virol. 81(4): 1951--1960 A novel repeat-associated small interfering RNA-mediated silencing pathway downregulates complementary sense gypsy transcripts in somatic cells of the Drosophila ovary. [FBrf0195158] Sarot et al., 2004, Genetics 166(3): 1313--1321 Evidence for a piwi-dependent RNA silencing of the gypsy endogenous retrovirus by the Drosophila melanogaster flamenco gene. [FBrf0174688] Mejlumian et al., 2002, Genetics 160(1): 201--209 Comparative and functional studies of Drosophila species invasion by the gypsy endogenous retrovirus. [FBrf0144889] Robert et al., 2001, Genetics 158(2): 701--713 Characterization of the flamenco Region of the Drosophila melanogaster Genome. [FBrf0136953] Chalvet et al., 1999, EMBO J. 18(9): 2659--2669 Proviral amplification of the gypsy endogenous retrovirus of Drosophila melanogaster involves env-independent invasion of the female germline. [FBrf0108442] Pelisson et al., 1997, Genetica 100(1-3): 29--37 About the origin of retroviruses and the co-evolution of the gypsy retrovirus with the Drosophila flamenco host gene. [FBrf0099792]

Allele Dmel\flamOR

Allele Dmel\flam^OR