Allele Scer\GAL4^vg.int2.1

General Information
Symbol	Scer\GAL4^vg.int2.1	Species	S. cerevisiae
Name		FlyBase ID	FBal0083444
Feature type	allele	Associated gene	Scer\GAL4

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Neumann and Cohen, 1996, Sun and Artavanis-Tsakonas, 1997)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\GAL4 expression is driven by the vg wing margin enhancer. (Sun and Artavanis-Tsakonas, 1997) Construct: Early vg enhancer drives Scer\GAL4 expression. (Neumann and Cohen, 1996)
Carried in construct	P{vg(int2.1)-GAL4} (Vaudin et al., 1999, Klebes et al., 2005, Guichard et al., 2002, Kolzer et al., 2003, Lee et al., 2005, Klein, 2002, Mishra-Gorur et al., 2002, Bennett and Alphey, 2002, Bessa et al., 2002, Cook et al., 2004, del Alamo Rodriguez et al., 2004, Verheyen et al., 2001, Casares and Mann, 2000, Varadarajan and VijayRaghavan, 1999, Klein and Martinez Arias, 1999, Sun and Artavanis-Tsakonas, 1997, Sustar and Schubiger, 2005, Zirin and Mann, 2004, Go et al., 1998, Klein, 2003, Vegh and Basler, 2003, Neumann and Cohen, 1996, Chew et al., 2004, Dussillol-Godar et al., 2006, Crickmore and Mann, 2006, Legent et al., 2006, Molnar et al., 2006, Zeng et al., 2007, Delanoue et al., 2004, Tortoriello et al., 2010, Link et al., 2007, Mendoza-Topaz et al., 2011, Becam et al., 2011)
Cytology
Phenotypic Data
Phenotypic Class
	viable, with Su(fu)^Scer\UAS.cDa (Dussillol-Godar et al., 2006) visible, with dap^Scer\UAS.cLa (Legent et al., 2006) visible, with Dl^{S.Scer\UAS.T:Hsap\MYC} (Sun and Artavanis-Tsakonas, 1997) visible, with H^Scer\UAS.cGa (Go et al., 1998) visible, with hth^{Scer\UAS.T:Avic\GFP} (Casares and Mann, 2000) visible, with Mad^Scer\UAS.cNa (Zeng et al., 2007) visible, with N^{ECN.Scer\UAS.cGa} (Go et al., 1998) visible, with Nop60B^GD16822 (Tortoriello et al., 2010) visible, with pan^Scer\UAS.cWa (Verheyen et al., 2001) visible, with sd^58d, sd^Scer\UAS.cVa (Legent et al., 2006) visible, with sd^Scer\UAS.cVa (Varadarajan and VijayRaghavan, 1999, Legent et al., 2006) visible, with Ser^{S.Scer\UAS.T:Hsap\MYC} (Sun and Artavanis-Tsakonas, 1997) visible, with Ser^Scer\UAS.cSa (Sun and Artavanis-Tsakonas, 1997)
Phenotype Manifest In
	axillary vein, with Su(fu)^Scer\UAS.cDa (Dussillol-Godar et al., 2006) costal vein, with Su(fu)^Scer\UAS.cDa (Dussillol-Godar et al., 2006) crossvein, with sd^58d, sd^Scer\UAS.cVa (Legent et al., 2006) crossvein, with sd^Scer\UAS.cVa (Legent et al., 2006) dorsal-ventral compartment boundary of the wing \| third instar larval stage, with ban^{C.Scer\UAS.T:Avic\GFP-EGFP} (Becam et al., 2011) dorsal-ventral compartment boundary of the wing \| third instar larval stage, with N^{dsRNA.P.Scer\UAS} (Becam et al., 2011) double row \| ectopic, with Sara^{F678A.Scer\UAS.T:Hsap\MYC,T:Zzzz\His6} (Bennett and Alphey, 2002) haltere, with Scer\GAL4^tub.PU, tkv^{dsRNA.Scer\UAS} (Crickmore and Mann, 2006, Crickmore and Mann, 2006) haltere disc, with Scer\GAL4^tub.PU, sbb^Scer\UAS.cYa (Crickmore and Mann, 2006) triple row, with Sara^{F678A.Scer\UAS.T:Hsap\MYC,T:Zzzz\His6} (Bennett and Alphey, 2002) wing, with dap^Scer\UAS.cLa (Legent et al., 2006) wing, with Dl^{A581S.Scer\UAS} (Mishra-Gorur et al., 2002) wing, with Dl^{A593S.Scer\UAS} (Mishra-Gorur et al., 2002) wing, with Dl^{S.Scer\UAS.T:Hsap\MYC} (Sun and Artavanis-Tsakonas, 1997) wing, with Dl^Scer\UAS.cDa (Mishra-Gorur et al., 2002) wing, with H^Scer\UAS.cGa (Go et al., 1998) wing, with hth^{Scer\UAS.T:Avic\GFP} (Casares and Mann, 2000) wing, with Mad^Scer\UAS.cNa (Zeng et al., 2007) wing, with N^{ECN.Scer\UAS.cGa} (Go et al., 1998) wing, with Scer\GAL4^tub.PU, tkv^{dsRNA.Scer\UAS} (Crickmore and Mann, 2006) wing, with Scer\GAL4^tub.PU, tkv^Scer\UAS.cNa (Crickmore and Mann, 2006) wing, with sd^58d, sd^Scer\UAS.cVa (Legent et al., 2006) wing, with sd^Scer\UAS.cVa (Varadarajan and VijayRaghavan, 1999, Legent et al., 2006) wing, with Ser^{S.Scer\UAS.T:Hsap\MYC} (Sun and Artavanis-Tsakonas, 1997) wing, with Ser^Scer\UAS.cSa (Sun and Artavanis-Tsakonas, 1997) wing \| posterior compartment, with put^Scer\UAS.cMa (Bennett and Alphey, 2002) wing \| somatic clone, with Axn^{EDDNmut.Scer\UAS.T:Avic\GFP} (Mendoza-Topaz et al., 2011) wing blade, with Nop60B^GD16822 (Tortoriello et al., 2010) wing blade, with sd^58d, sd^Scer\UAS.cVa (Legent et al., 2006) wing blade, with sd^Scer\UAS.cVa (Legent et al., 2006) wing disc, with dpp^Scer\UAS.cSa (Klein and Martinez Arias, 1999) wing disc, with hth^{Scer\UAS.T:Avic\GFP} (Casares and Mann, 2000) wing disc, with N^ICN.Scer\UAS (Go et al., 1998) wing disc, with sd^Scer\UAS.cVa (Varadarajan and VijayRaghavan, 1999) wing hinge, with sd^58d, sd^Scer\UAS.cVa (Legent et al., 2006) wing hinge, with sd^Scer\UAS.cVa (Legent et al., 2006) wing margin, with Axn^{FGmut.Scer\UAS.T:Avic\GFP} (Mendoza-Topaz et al., 2011) wing margin, with Nop60B^GD16822 (Tortoriello et al., 2010) wing margin, with rho^Neo.Scer\UAS (Guichard et al., 2002) wing margin, with Su(fu)^Scer\UAS.cDa (Dussillol-Godar et al., 2006) wing margin \| anterior compartment, with Sara^{F678A.Scer\UAS.T:Hsap\MYC,T:Zzzz\His6} (Bennett and Alphey, 2002) wing margin \| anterior compartment, with tkv^{Q253D.Scer\UAS.cNb} (Bennett and Alphey, 2002) wing margin \| posterior, with pan^Scer\UAS.cWa (Verheyen et al., 2001) wing margin \| posterior compartment, with Sara^{F678A.Scer\UAS.T:Hsap\MYC,T:Zzzz\His6} (Bennett and Alphey, 2002) wing margin \| posterior compartment, with Sara^{Scer\UAS.T:Hsap\MYC,T:Zzzz\His6} (Bennett and Alphey, 2002) wing margin bristle, with hth^{Scer\UAS.T:Avic\GFP} (Casares and Mann, 2000) wing margin bristle, with Nop60B^GD16822 (Tortoriello et al., 2010) wing margin bristle \| anterior compartment, with tkv^{Q253D.Scer\UAS.cNb} (Bennett and Alphey, 2002) wing vein, with brk^Scer\UAS.cJa (Cook et al., 2004) wing vein, with sd^58d, sd^Scer\UAS.cVa (Legent et al., 2006) wing vein, with sd^Scer\UAS.cVa (Legent et al., 2006) wing vein \| ectopic, with bi^Scer\UAS.cBa (Cook et al., 2004) wing vein \| ectopic, with Mad^Scer\UAS.cNa (Zeng et al., 2007) wing vein L5, with bi^Scer\UAS.cBa (Cook et al., 2004) wing vein L5, with Sara^{F678A.Scer\UAS.T:Hsap\MYC,T:Zzzz\His6} (Bennett and Alphey, 2002) wing vein L5, with tkv^{Q253D.Scer\UAS.cNb} (Bennett and Alphey, 2002)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement Reference Mad^Scer\UAS.cNa, Scer\GAL4^vg.int2.1 has visible phenotype, enhanceable by rl[+]/rl^Sem (Zeng et al., 2007) Mad^Scer\UAS.cNa, Scer\GAL4^vg.int2.1 has visible phenotype, enhanceable by rl^{Sem.S.Scer\UAS}, Scer\GAL4^vg.int2.1 (Zeng et al., 2007, Zeng et al., 2007) Scer\GAL4^vg.int2.1, dap^Scer\UAS.cLa has visible phenotype, enhanceable by vg[+]/vg^null (Legent et al., 2006) Scer\GAL4^vg.int2.1, sd^Scer\UAS.cVa has visible phenotype, enhanceable by vg[+]/vg^null (Legent et al., 2006)
Suppressed by
Statement Reference BacA\p35^Scer\UAS.cHa, Dp^Scer\UAS.cDa, E2f^Scer\UAS.cNa, Scer\GAL4^vg.int2.1 has visible phenotype, suppressible \| partially by vg[+]/vg^null (Legent et al., 2006) H^Scer\UAS.cGa, Scer\GAL4^vg.int2.1 has visible phenotype, suppressible by N^ICN.Scer\UAS, Scer\GAL4^vg.int2.1 (Go et al., 1998, Go et al., 1998) Mad^Scer\UAS.cNa, Scer\GAL4^vg.int2.1 has visible phenotype, suppressible by nmo^Scer\UAS.cUa, Scer\GAL4^vg.int2.1 (Zeng et al., 2007, Zeng et al., 2007) Scer\GAL4^vg.int2.1, dap^Scer\UAS.cLa, vg[+]/vg^null has visible phenotype, suppressible by vg^Scer\UAS.cZa/Scer\GAL4^vg.int2.1 (Delanoue et al., 2004, Delanoue et al., 2004)
Enhancer of
Statement Reference rl^{Sem.S.Scer\UAS}, Scer\GAL4^vg.int2.1 is an enhancer of visible phenotype of Mad^Scer\UAS.cNa, Scer\GAL4^vg.int2.1 (Zeng et al., 2007, Zeng et al., 2007)
Suppressor of
Statement Reference E2f^Scer\UAS.cNa, Dp^Scer\UAS.cDa, Scer\GAL4^vg.int2.1, BacA\p35^Scer\UAS.cHa is a suppressor \| partially of visible phenotype of vg^83b27 (Legent et al., 2006) Hsap\VGLL1^Scer\UAS.cVa/Scer\GAL4^vg.int2.1 is a suppressor \| partially of visible \| recessive phenotype of vg^83b27 (Vaudin et al., 1999) N^ICN.Scer\UAS, Scer\GAL4^vg.int2.1 is a suppressor of visible phenotype of H^Scer\UAS.cGa, Scer\GAL4^vg.int2.1 (Go et al., 1998, Go et al., 1998) nmo^Scer\UAS.cUa, Scer\GAL4^vg.int2.1 is a suppressor of visible phenotype of Mad^Scer\UAS.cNa, Scer\GAL4^vg.int2.1 (Zeng et al., 2007, Zeng et al., 2007) vg^Scer\UAS.cZa/Scer\GAL4^vg.int2.1 is a suppressor of visible phenotype of Scer\GAL4^vg.int2.1, dap^Scer\UAS.cLa, vg[+]/vg^null (Delanoue et al., 2004, Delanoue et al., 2004)
Phenotype Manifest In
Enhanced by
Statement Reference Mad^Scer\UAS.cNa, Scer\GAL4^vg.int2.1 has wing phenotype, enhanceable by rl[+]/rl^Sem (Zeng et al., 2007) Mad^Scer\UAS.cNa, Scer\GAL4^vg.int2.1 has wing phenotype, enhanceable by rl^{Sem.S.Scer\UAS}, Scer\GAL4^vg.int2.1 (Zeng et al., 2007, Zeng et al., 2007) Mad^Scer\UAS.cNa, Scer\GAL4^vg.int2.1 has wing vein \| ectopic phenotype, enhanceable by rl[+]/rl^Sem (Zeng et al., 2007) Mad^Scer\UAS.cNa, Scer\GAL4^vg.int2.1 has wing vein \| ectopic phenotype, enhanceable by rl^{Sem.S.Scer\UAS}, Scer\GAL4^vg.int2.1 (Zeng et al., 2007, Zeng et al., 2007) Scer\GAL4^vg.int2.1, dap^Scer\UAS.cLa has wing phenotype, enhanceable by vg[+]/vg^null (Legent et al., 2006) Scer\GAL4^vg.int2.1, put^Scer\UAS.cMa has wing \| posterior compartment phenotype, enhanceable by Df(3R)crb87-5/+ (Bennett and Alphey, 2002) Scer\GAL4^vg.int2.1, put^Scer\UAS.cMa has wing \| posterior compartment phenotype, enhanceable by Pp1-87B[+]/Pp1-87B¹ (Bennett and Alphey, 2002) Scer\GAL4^vg.int2.1, put^Scer\UAS.cMa has wing \| posterior compartment phenotype, enhanceable by Pp1-87B[+]/Pp1-87B^87Bg-6 (Bennett and Alphey, 2002) Scer\GAL4^vg.int2.1, put^Scer\UAS.cMa has wing \| posterior compartment phenotype, enhanceable by Pp1-87B^87Bg-3/Pp1-87B[+]/Df(3R)crb87-5/+ (Bennett and Alphey, 2002) Scer\GAL4^vg.int2.1, sd^Scer\UAS.cVa has wing blade phenotype, enhanceable by vg[+]/vg^null (Legent et al., 2006) Scer\GAL4^vg.int2.1, sd^Scer\UAS.cVa has wing hinge phenotype, enhanceable by vg[+]/vg^null (Legent et al., 2006) Scer\GAL4^vg.int2.1, sd^Scer\UAS.cVa has wing phenotype, enhanceable by vg[+]/vg^null (Legent et al., 2006)
Suppressed by
Statement Reference BacA\p35^Scer\UAS.cHa, Dp^Scer\UAS.cDa, E2f^Scer\UAS.cNa, Scer\GAL4^vg.int2.1 has wing phenotype, suppressible \| partially by vg[+]/vg^null (Legent et al., 2006) H^Scer\UAS.cGa, Scer\GAL4^vg.int2.1 has wing phenotype, suppressible by N^ICN.Scer\UAS, Scer\GAL4^vg.int2.1 (Go et al., 1998, Go et al., 1998) Mad^Scer\UAS.cNa, Scer\GAL4^vg.int2.1 has wing phenotype, suppressible by nmo^Scer\UAS.cUa, Scer\GAL4^vg.int2.1 (Zeng et al., 2007, Zeng et al., 2007) Mad^Scer\UAS.cNa, Scer\GAL4^vg.int2.1 has wing vein \| ectopic phenotype, suppressible by nmo^Scer\UAS.cUa, Scer\GAL4^vg.int2.1 (Zeng et al., 2007, Zeng et al., 2007) N^{dsRNA.P.Scer\UAS}, Scer\GAL4^vg.int2.1 has dorsal-ventral compartment boundary of the wing \| third instar larval stage phenotype, suppressible \| partially by Disc\RFP^{dsRed.Scer\UAS.ban-sponge}, Scer\GAL4^vg.int2.1 (Becam et al., 2011, Becam et al., 2011) Scer\GAL4^vg.int2.1, dap^Scer\UAS.cLa, vg[+]/vg^null has wing phenotype, suppressible by vg^Scer\UAS.cZa/Scer\GAL4^vg.int2.1 (Delanoue et al., 2004, Delanoue et al., 2004)
Enhancer of
Statement Reference rl^{Sem.S.Scer\UAS}, Scer\GAL4^vg.int2.1 is an enhancer of wing phenotype of Mad^Scer\UAS.cNa, Scer\GAL4^vg.int2.1 (Zeng et al., 2007, Zeng et al., 2007) rl^{Sem.S.Scer\UAS}, Scer\GAL4^vg.int2.1 is an enhancer of wing vein \| ectopic phenotype of Mad^Scer\UAS.cNa, Scer\GAL4^vg.int2.1 (Zeng et al., 2007, Zeng et al., 2007)
Suppressor of
Statement Reference Dcr-1^GD11429/Scer\GAL4^vg.int2.1 is a suppressor \| partially of dorsal-ventral compartment boundary of the wing \| third instar larval stage phenotype of N^{dsRNA.P.Scer\UAS} (Becam et al., 2011) Disc\RFP^{dsRed.Scer\UAS.ban-sponge}, Scer\GAL4^vg.int2.1 is a suppressor \| partially of dorsal-ventral compartment boundary of the wing \| third instar larval stage phenotype of N^{dsRNA.P.Scer\UAS}, Scer\GAL4^vg.int2.1 (Becam et al., 2011, Becam et al., 2011) E2f^Scer\UAS.cNa, Dp^Scer\UAS.cDa, Scer\GAL4^vg.int2.1, BacA\p35^Scer\UAS.cHa is a suppressor \| partially of wing blade phenotype of vg^83b27 (Legent et al., 2006) Hsap\VGLL1^Scer\UAS.cVa/Scer\GAL4^vg.int2.1 is a suppressor \| partially of wing phenotype of vg^83b27 (Vaudin et al., 1999) N^ICN.Scer\UAS, Scer\GAL4^vg.int2.1 is a suppressor of wing phenotype of H^Scer\UAS.cGa, Scer\GAL4^vg.int2.1 (Go et al., 1998, Go et al., 1998) nmo^Scer\UAS.cUa, Scer\GAL4^vg.int2.1 is a suppressor of wing phenotype of Mad^Scer\UAS.cNa, Scer\GAL4^vg.int2.1 (Zeng et al., 2007, Zeng et al., 2007) nmo^Scer\UAS.cUa, Scer\GAL4^vg.int2.1 is a suppressor of wing vein \| ectopic phenotype of Mad^Scer\UAS.cNa, Scer\GAL4^vg.int2.1 (Zeng et al., 2007, Zeng et al., 2007) th^Scer\UAS.cLa/Scer\GAL4^vg.int2.1 is a suppressor of wing \| conditional phenotype of vg^null (Delanoue et al., 2004) vg^Scer\UAS.cZa/Scer\GAL4^vg.int2.1 is a suppressor of wing phenotype of Scer\GAL4^vg.int2.1, dap^Scer\UAS.cLa, vg[+]/vg^null (Delanoue et al., 2004, Delanoue et al., 2004)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	GAL4^vg.int2.1 Scer\GAL4^vg.int2.1
Name Synonym
Secondary FlyBase IDs

References ( 34 )

Generate a list of	All references relating to this allele ( 34 )

List References by type	Research paper ( 33 ) Supplementary material ( 1 )
Recent research papers ( 2 )
	Becam et al., 2011, Development 138(17): 3781--3789 Notch-mediated repression of bantam miRNA contributes to boundary formation in the Drosophila wing. [FBrf0214603] Mendoza-Topaz et al., 2011, Open Biol. 1(3): 110013 The Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin's interaction with Dishevelled. [FBrf0218486] Show all research papers ...

Allele Scer\GAL4vg.int2.1

Allele Scer\GAL4^vg.int2.1