FlyBase Allele Report: Dmel\ss[a40aw]

General Information

Symbol

Dmel\ss^a40aw

Species

D. melanogaster

Name

FlyBase ID

FBal0083731

Feature type

allele

Associated gene

Dmel\ss

Associated Insertion(s)

Carried in Construct

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Cytology

Nature of the lesion

Statement

Reference

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

antennal segment

(Kuzin et al., 1997)

mesothoracic tarsal segment

(Kuzin et al., 1997)

metathoracic tarsal segment

(Kuzin et al., 1997)

prothoracic tarsal segment

(Kuzin et al., 1997)

Detailed Description

Statement

Reference

Homozygotes exhibit a minimal degree of transformation of arista to tarsus, phenotype is not sensitive to temperature. Hemizygotes exhibit incomplete tarsal segmentation, segmentation is more strongly suppressed at 18^oC. Fusion of the segments is less manifested in the second leg, as compared with the first, third and homeotic tarsus on the antenna.

(Kuzin et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

pb^hs.PB, ss^a40aw has visible phenotype

(Kuzin et al., 1997)

Df(3R)P10, ss^a40aw has visible phenotype

(Kuzin et al., 1997)

lab^hs.PH, ss^a40aw has visible phenotype

(Kuzin et al., 1997)

Phenotype Manifest In

Suppressed by

Statement

Reference

Pc³, ss^a40aw has sex comb | ectopic phenotype, suppressible by trx^B22

(Kuzin et al., 1997)

Other

Statement

Reference

pb^hs.PB, ss^a40aw has tarsal segment phenotype

(Kuzin et al., 1997)

Df(3R)P10, ss^a40aw has metathoracic tarsal segment phenotype

(Kuzin et al., 1997)

pb^hs.PB, ss^a40aw has antennal segment phenotype

(Kuzin et al., 1997)

Pc³, ss^a40aw has sex comb | ectopic phenotype

(Kuzin et al., 1997)

lab^hs.PH, ss^a40aw has third segment of antenna phenotype

(Kuzin et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

Loss of Ubx suppresses the defective tarsal segmentation phenotype on the third leg. ss^a40aw flies carrying Pc³ exhibit sex combs on the tarsi of each leg. At lower temperatures, the number of teeth increases and segmentation of the leg is highly suppressed. Introduction of trx^B22 completely neutralizes the negative effect of Pc on the formation of tarsal structures. Induction of lab^hs.PH expression causes overgrowth of the third antennal segment without the formation of multiple bristles. Induction of pb^hs.PB expression causes shortening of the distal parts of the tarsus, mostly in the antennae, legs are less affected.

(Kuzin et al., 1997)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

ss^a40aw

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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