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General Information
Symbol
Dmel\sqhA21.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0083733
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Contains sqh, expressed under its own promoter and containing the amino acid replacement S21A, tagged with Tag:FLAG.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

One copy of sqhA21.T:Zzzz\FLAG in a wild-type background has no effect on eye development.

Approximately 10-20% of egg chambers in germline clones expressing sqhA21.T:Zzzz\FLAG apparently have a failure of cytokinesis during the fourth round of cystocyte division as they consist of 7 binuclear nurse cells and one binuclear oocyte. A fraction of eggs derived from germline clones expressing sqhA21.T:Zzzz\FLAG are deposited and have three or four dorsal appendages. The four appendages are found in two pairs separated by a variable fraction of the egg circumference. When three appendages are present, the central one often appears to be a fusion of two appendages. Eggs with three or four dorsal appendages can be fertilised and begin development. These embryos have posterior segmentation defects. Only 36% of these embryos show partial dorsalisation (reduced head skeleton and a narrowing of the denticle belts).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

sqhA21.Tag:FLAG is an enhancer of visible | recessive phenotype of dsh1

NOT Enhancer of
Suppressor of
Statement
Reference
NOT Suppressor of
Phenotype Manifest In
Enhancer of
Statement
Reference
NOT Enhancer of
Suppressor of
Statement
Reference
NOT Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference

MbsT541 photoreceptor clones are restored to their wild-type apical location in the eye disc when discs carry one copy of the constitutively inactive the sqhA21.T:Zzzz\FLAG transgene.

The viability of both flwG0172 and flw6 mutants is much greater in a sqhA21.T:Zzzz\FLAG background than a sqhA20.T:Zzzz\FLAG background.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
sqhA21.T:FLAG
sqhA21.T:Zzzz\FLAG
sqhA21.Tag:FLAG
Name Synonyms
Secondary FlyBase IDs
    References (6)