Allele Ecol\lacZ^sty-09143

General Information
Symbol	Ecol\lacZ^sty-09143	Species	E. coli
Name		FlyBase ID	FBal0083865
Feature type	allele	Associated gene	Ecol\lacZ

Map ( GBrowse )	Untitled Document
Allele class
Mutagen	P-element activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	P-element activity (Hacohen et al., 1998)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site 3L:3,450,279..3,450,279 (Samakovlis et al., 1996, Iwanami et al., 2005, Steneberg et al., 1998, Franzdóttir et al., 2009, Sen et al., 2004, Englund et al., 1999, Casci et al., 1999, Kramer et al., 1999, Imam et al., 1999, FlyBase, 1996-, Vosshall, 1998.8.10, Lee and Treisman, 2001, Hacohen et al., 1998, Pallavi et al., 2006)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	P{PZ}eIF5B⁰⁹¹⁴³ (Samakovlis et al., 1996, Iwanami et al., 2005, Steneberg et al., 1998, Franzdóttir et al., 2009, Sen et al., 2004, Englund et al., 1999, Casci et al., 1999, Kramer et al., 1999, Imam et al., 1999, FlyBase, 1996-, Vosshall, 1998.8.10, Lee and Treisman, 2001, Hacohen et al., 1998, Pallavi et al., 2006)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 1 )
Bloomington	11735 P{PZ}eIF5B⁰⁹¹⁴³, l(3)09143⁰⁹¹⁴³ ry⁵⁰⁶/TM3, ry^RK Sb¹ Ser¹
Notes on Origin
Discoverer
	The lethality of the "09143" chromosome is separable from the P{PZ}eIF5B⁰⁹¹⁴³ insertion (the insertion is an enhancer trap marker of sty). (Hacohen et al., 1998) Separable from: l(3)09143⁰⁹¹⁴³. The P{PZ}eIF5B⁰⁹¹⁴³ insertion (flanking sequence G00521) maps within eIF5B but appears to be an enhancer trap of sty, the next gene downstream (see FBrf0100567). (FlyBase, 1996-)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	Ecol\lacZ^sty-09143 l(3)01943 (Casci et al., 1999) lacZ^sty-09143 Pantip-2 (Samakovlis et al., 1996)
Name Synonym
Secondary FlyBase IDs
	FBal0055628
References ( 16 )
Research paper	Franzdóttir et al., 2009, Nature 460(7256): 758--761 Switch in FGF signalling initiates glial differentiation in the Drosophila eye. [FBrf0208713] Pallavi et al., 2006, Dev. Biol. 296(2): 340--352 Negative regulation of Egfr/Ras pathway by Ultrabithorax during haltere development in Drosophila. [FBrf0195051] Iwanami et al., 2005, Genes Cells 10(7): 743--752 Cell-type specific utilization of multiple negative feedback loops generates developmental constancy. [FBrf0187603] Sen et al., 2004, Mech. Dev. 121(1): 65--78 Programmed cell death and context dependent activation of the EGF pathway regulate gliogenesis in the Drosophila olfactory system. [FBrf0167846] Campbell, 2002, Nature 418(6899): 781--785 Distalization of the Drosophila leg by graded EGF-receptor activity. [FBrf0151696] Lee and Treisman, 2001, Curr. Biol. 11(14): 1147--1152 Sightless has homology to transmembrane acyltransferases and is required to generate active Hedgehog protein. [FBrf0137202] Casci et al., 1999, Cell 96(5): 655--665 Sprouty, an intracellular inhibitor of Ras signaling. [FBrf0107641] Englund et al., 1999, Development 126(7): 1505--1514 adrift, a novel bnl-induced Drosophila gene, required for tracheal pathfinding into the CNS. [FBrf0108176] Imam et al., 1999, Genetics 152(1): 307--318 stumps, a Drosophila gene required for fibroblast growth factor (FGF)-directed migrations of tracheal and mesodermal cells. [FBrf0108206] Kramer et al., 1999, Development 126(11): 2515--2525 Sprouty: a common antagonist of FGF and EGF signaling pathways in Drosophila. [FBrf0108521] Hacohen et al., 1998, Cell 92(2): 253--263 sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. [FBrf0100567] Steneberg et al., 1998, Genes Dev. 12(7): 956--967 Translational readthrough in the hdc mRNA generates a novel branching inhibitor in the Drosophila trachea. [FBrf0101899] Samakovlis et al., 1996, Development 122(5): 1395--1407 Development of the Drosophila tracheal system occurs by a series of morphologically distinct but genetically coupled branching events. [FBrf0087684]
Personal communication to FlyBase	Vosshall, 1998.8.10, Patterns of lacZ expression. Patterns of lacZ expression. [FBrf0103142] Meister and Braun, 1995.10, lacZ expression patterns for P{} insertions at Bloomington. lacZ expression patterns for P{} insertions at Bloomington. [FBrf0083714]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946]

Allele Ecol\lacZsty-09143

Allele Ecol\lacZ^sty-09143