Allele Dmel\Snap25^hs.PW

General Information
Symbol	Dmel\Snap25^hs.PW	Species	D. melanogaster
Name	heat shock construct of Wu	FlyBase ID	FBal0085913
Feature type	allele	Associated gene	Dmel\Snap25

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Wu et al., 1998)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: Full length Snap25 cDNA is expressed under the control of an Hsp70 promoter. (Wu et al., 1998)
Carried in construct	P{hs-Snap25.W} (Nie et al., 1999, Wu et al., 1998)
Cytology
Phenotypic Data
Phenotypic Class
	viable (Nie et al., 1999)
Phenotype Manifest In

Detailed Description
	Statement Reference Flies carrying Snap25^hs.PW are viable and have normal wings and eyes at 25^oC. (Nie et al., 1999) Overexpression of Snap25^hs.PW causes no defects in either the amplitude of the excitatory junctional potential (EJP), or the frequency of miniature EJPs in the muscle at the larval neuromuscular junction. Snap25^hs.PW does not alter the physiological defects seen in the muscle at the larval neuromuscular junction of flies overexpressing Rop^hs.PS when coexpressed with Rop^hs.PS. (Wu et al., 1998)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Snap25^hs.PW
Name Synonym	heat shock construct of Wu (Wu et al., 1998)
Secondary FlyBase IDs

References ( 2 )
Research paper	Nie et al., 1999, J. Neurosci. 19(23): 10270--10279 Overexpression of cysteine-string proteins in Drosophila reveals interactions with syntaxin. [FBrf0111989] Wu et al., 1998, EMBO J. 17(1): 127--139 ROP, the Drosophila Sec1 homolog, interacts with syntaxin and regulates neurotransmitter release in a dosage-dependent manner. [FBrf0100401]

Allele Dmel\Snap25hs.PW

Allele Dmel\Snap25^hs.PW