loss of function allele
R264term | RhoGEF2-PD; R264term | RhoGEF2-PE; R264term | RhoGEF2-PF; R264term | RhoGEF2-PG; R264term | RhoGEF2-PH
Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.
Amino acid replacement: R264term.
lethal (with RhoGEF24.1)
Late embryos from RhoGEF24.4 heterozygous mothers display a wild-type cuticle pattern, as compared to controls.
RhoGEF24.4/RhoGEF24.1 animals show 98% embryonic viability, 97% first larval instar viability and 0% adult viability.
RhoGEF24.4 is a suppressor of visible phenotype of Rho1GMR.PH
RhoGEF2[+]/RhoGEF24.4 is an enhancer of embryonic/larval cuticle | ventral | maternal effect | embryonic stage phenotype of tslΔ
RhoGEF24.4 is a suppressor of eye phenotype of Rho1GMR.PH
RhoGEF24.4 heterozygosity strongly enhances the ventral cuticle defects displayed by late embryos from tslΔ homozygous mothers, leading to fully penetrant absence of ventral cuticle.
Dominantly suppresses the Rho1GMR.PH rough eye phenotype.
Isolated as a dominant suppressor of the Rho1GMR.PH rough eye phenotype.