FB2025_01 , released February 20, 2025
Allele: Dmel\styG5
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General Information
Symbol
Dmel\styG5
Species
D. melanogaster
Name
FlyBase ID
FBal0086310
Feature type
allele
Associated gene
Dmel\sty
Associated Insertion(s)
Carried in Construct
Also Known As
spryG5
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Hacohen et al., 1998)
Progenitor genotype
Cytology
Description

Nucleotide substitution: G2710A.

(Kramer et al., 1995)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Escapers of lethality show a disorganized eye phenotype. Majority of ommatidia have extra R7 cells, generated by transformation of cone cells. Some of the extra photoreceptors resemble outer (R1-R6) photoreceptor neurons. Mystery cells assume R3/R4 fates. In heterozygous condition, 1-7% of ommatidia show an extra R7 cell or an occasional gain or loss of an outer photoreceptor cell.

      (Kramer et al., 1999)

      Pupal lethal when hemizygous. The number of tracheal branches emanating from the dorsal and ganglionic branches is higher than normal in homozygous embryos.

      (Kramer et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: Dominant suppressor of the rough eye phenotype caused by ectopic expression of svp in photoreceptors R2 and R5.

      (Kramer et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      spryG5
      (Kramer et al., 1999, Hacohen et al., 1998)
      styG5
      Name Synonyms
      Secondary FlyBase IDs
        References (3)