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General Information
Symbol
Dmel\styF7
Species
D. melanogaster
Name
FlyBase ID
FBal0086311
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
spryF7
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Nucleotide substitution: C2466T.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Escapers of lethality show a disorganized eye phenotype. Majority of ommatidia have extra R7 cells, generated by transformation of cone cells. Some of the extra photoreceptors resemble outer (R1-R6) photoreceptor neurons. Mystery cells assume R3/R4 fates. In heterozygous condition, 1-7% of ommatidia show an extra R7 cell or an occasional gain or loss of an outer photoreceptor cell.

Pupal lethal when hemizygous. The number of tracheal branches emanating from the dorsal and ganglionic branches is higher than normal in homozygous embryos.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference
Suppressor of
Statement
Reference
Phenotype Manifest In
Suppressed by
Statement
Reference
Enhancer of
Statement
Reference

styF7 is an enhancer of ommatidium phenotype of fz20/fz19

Suppressor of
Statement
Reference

styF7 is a suppressor of ommatidium phenotype of Ras64BV14.Act5C

Additional Comments
Genetic Interactions
Statement
Reference

The addition of styF7/+ enhances the eye cell polarity phenotype seen in fz19/fz20 animals. Heterozygotes suppress the ommatidial polarity defects seen in Ras64BV14.Act5C.

The extra R7 cells of styF7 are suppressed in ommatidia also mutant for Ras85DN17.hs.2sev.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Selected as: Dominant suppressor of the rough eye phenotype caused by ectopic expression of svp in photoreceptors R2 and R5.

Comments
Comments

Amorph or strong hypomorph.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (4)