Imprecise excision of the P{lacW} element present in the P{lacW}s2683 insertion, removing the 5' exon common to all splice forms of sty.
styΔ5/+ does not cause significant cardiac enlargement or reduced fractional shortening in adult hearts.
Eggs derived from egg chambers containing complete homozygous follicle cell clones have an expanded dorsal midline region, with the dorsal appendages being further apart than normal. In addition, most of the appendages are mildly shorter in length or thicker in width than normal, some have branched tips, and rarely, a small pseudo-appendage is seen at the base of one of the appendages.
Eggs derived from females with mosaic styΔ5 egg chambers occasionally have multiple, ectopic dorsal appendages. More commonly, the eggs have thinner dorsal appendages that are located more laterally than normal.
styΔ5 larva show extra terminal cells in their tracheal systems, when compared to wild-type larva.
styΔ5 homozygous clones in the dorsal air sac primordium are found at the tip of the primordium at a significantly lower frequency than wild-type clones.
Homozygotes have a variable number of outer photoreceptor neurons per ommatidium; some ommatidia have more and some have fewer than the normal number of outer photoreceptor neurons, and although the average number is 6.01 per ommatidium in the mutant (almost the same as wild type), the standard deviation is large (1.05).
When mutant somatic clones are made in the border cells no effect is seen.
Homozygous eggs are not recovered from females containing homozygous germ line clones, suggesting a requirement for sty function in the germline.
Escapers of lethality show a disorganized eye phenotype. Majority of ommatidia have extra R7 cells, generated by transformation of cone cells. Some of the extra photoreceptors resemble outer (R1-R6) photoreceptor neurons. Mystery cells assume R3/R4 fates. In heterozygous condition, 1-7% of ommatidia show an extra R7 cell or an occasional gain or loss of an outer photoreceptor cell. In embryos, 26% of hemisegments show an extra chordotonal organ in the lateral cluster. Midline glial cells are increased in number.
When clones are induced in the ovary, or specifically in the follicle cells, a range of phenotypes occurs, depending on the size of the clone. Eggs may be dorsalized, dorsal appendages may be misplaced or enlarged, and, rarely, dorsal appendages may be duplicated or split.
Pupal lethal when hemizygous. 30-120% more tracheal branches than normal bud from the dorsal, lateral trunk anterior, lateral trunk posterior, ganglionic and visceral branches. These additional branches arise from the stalks of the primary branches, close to the positions where secondary and terminal branches normally bud. The total number of tracheal cells is not increased in these embryos. In homozygous clones in which only the tracheal tip cell GB1 is sty-, there is always an ectopic branch in the neighbouring sty+ stalk cell, GB2. These ectopic branches usually turn away from the ventral nerve cord, and growth of the normal branch from the sty- GB1 cell may be slowed. In contrast, in clones in which a subset of stalk cells (GB2-7) are sty- and GB1 is sty+, the ganglionic branch generally appears normal, with no ectopic branches. In clones in which the tracheal tip cell DB1 is sty-, nearby sty+ cells form ectopic branches.
sty[+]/styΔ5 is an enhancer of visible phenotype of Chmp1GD11219, Scer\GAL4Bx-MS1096
styΔ5 is an enhancer of cell polarity defective phenotype of fz20/fz19
styΔ5 is a suppressor of cell polarity defective phenotype of Ras64BV14.Act5C
styΔ5 is a suppressor of visible phenotype of Pp2B-14Dact.GMR
styΔ5 is a suppressor of visible phenotype of CanBGMR.PS, Pp2B-14Dact.GMR
sty[+]/styΔ5 is a non-suppressor of size defective | adult stage phenotype of Pp2B-14Dact.UAS.EYFP, Scer\GAL4tin.CΔ4
sty[+]/styΔ5 is an enhancer of wing vein phenotype of Chmp1GD11219, Scer\GAL4Bx-MS1096
sty[+]/styΔ5 is an enhancer of wing vein | ectopic phenotype of Hsap\ATN1N917.65Q.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
sty[+]/styΔ5 is an enhancer of photoreceptor cell R7 | supernumerary phenotype of csw::Src64Bhs.2sev
styΔ5 is an enhancer of ommatidium phenotype of fz20/fz19
styΔ5 is an enhancer of ommatidium phenotype of KrIf-1
sty[+]/styΔ5 is a suppressor | partially of adult heart phenotype of Pp2B-14Dact.UAS.EYFP, Scer\GAL4tin.CΔ4
sty[+]/styΔ5 is a suppressor of eye phenotype of rauf04153/Df(2L)rauΔ
styΔ5 is a suppressor of eye photoreceptor cell | somatic clone phenotype of mopT612
sty[+]/styΔ5 is a suppressor | partially of outer photoreceptor cell phenotype of cswG547E.hs.2sev
styΔ5 is a suppressor of ommatidium phenotype of Ras64BV14.Act5C
styΔ5 is a suppressor of eye phenotype of Pp2B-14Dact.GMR
styΔ5 is a suppressor of eye phenotype of CanBGMR.PS, Pp2B-14Dact.GMR
sty[+]/styΔ5 is a non-suppressor of outer photoreceptor cell phenotype of cswCS.hs.2sev
aosΔ7, styΔ5 has ommatidial precursor cluster | somatic clone phenotype
styΔ5/+ rescues the reduced fractional shortening phenotype but not the cardiac enlargement of flies expressing Pp2B-14Dact.Scer\UAS.T:Avic\GFP-EYFP under the control of Scer\GAL4tin.CΔ4.
styΔ5/+ suppresses the rough eye of Df(2L)rauΔ adults and the 'R7 cell loss' phenotype seen in Df(2L)rauΔ eye discs.
Flies that express one copy of csw::Src64Bhs.2sev in developing eyes with a styΔ5/+ background show an enhancement of the extra R7 photoreceptor cell phenotype seen when csw::Src64Bhs.2sev is expressed in a wild-type background. A higher proportion of the csw::Src64Bhs.2sev/+; styΔ5/+ flies show 3, 4, 5,or 6 R7 photoreceptor cells per ommatidium.
The addition of styΔ5/+ enhances the eye cell polarity phenotype seen in fz19/fz20 animals. Heterozygotes suppress the ommatidial polarity defects seen in Ras64BV14.Act5C.
Weakly suppresses the eye phenotype produced by activated arm constructs. (either armS44Y.GMR or armS56F.GMR).
Eyes mutant for both styΔ5 and carrying argosGMR.PS have a normal-size eye and an extra-R7 phenotype similar to that of styΔ5 alone.
The ectopic wing vein phenotype seen when Hsap\ATN1N917.65Q.Scer\UAS is expressed under the control of Scer\GAL4GMR.PF is enhanced in styΔ5 heterozygotes.
Amorph or strong hypomorph.