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General Information
Symbol
Dmel\smounspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0086334
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference
    Homozygous clones in the anterior compartment of A10-11 easily integrate among posterior compartment cells of the corresponding segment. However, homozygous clones in the anterior compartment of A10-11 that abut the segmental border do not integrate with the posterior compartment cells of A9 (the male genital primordium), and remain in the anterior of A10-11.
    Homozygous smounspecified clones in the haed produce animals with head capsule defects.
    Somatic stem cell proliferation requires smo activity.
    Three days after induction, homozygous clones in the ovary are found to have proliferated like wild-type cells and do not induce any aberrant phenotypes. However, 8 days after induction the mutant clones are much smaller and are recovered at a much lower frequency than control clones. Approximately 10% of ovarioles include an enlarged germarial region 3 (indicative of arrested budding), compound egg chambers or closely apposed egg chambers with no stalk between them. The affected egg chambers are often composed largely of homozygous cells, although in some compound, or partially fused egg chambers, no mutant cells are seen. In many morphologically normal ovarioles, mutant cells are found to contribute substantially to individual egg chambers of normal polarity.
    All denticles in abdominal segments point posteriorly in smounspecified mutant embryos. At 18oC, naked cuticle is deleted and denticle belts of adjacent segments are fused and locally arranged as mirror image duplications.
    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    NOT Enhancer of
    Statement
    Reference
    smo[+]/smounspecified is a non-enhancer of denticle belt phenotype of Cow
    NOT Suppressor of
    Statement
    Reference
    smo[+]/smounspecified is a non-suppressor of denticle belt phenotype of Cow
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    smounspecified cadunspecified double mutant clones are incapable of straddling the segmental border between A9 and A10-11.
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    smounspecified
    Name Synonyms
    Secondary FlyBase IDs
      References (9)