FlyBase Allele Report: Dmel\puc[UAS.cMa]

Embryos expressing puc^Scer\UAS.cMa under the control of Scer\GAL4^ptc-559.1 completely lack cell intercalation and mixer cell shifting at the segment boundary during dorsal closure (in the abdominal segments of wild-type embryos at the end of dorsal closure, a mixer cell moves across the segment boundary from the anterior compartment to the posterior compartment and two cells from the ventral ectoderm intercalate into the leading edge, posterior to the mixer cell).

(Gettings et al., 2010)

Overexpression of puc^Scer\UAS.cMa driven by Scer\GAL4^Abd-B-LDN induces abnormal male terminalia rotation without genital arch defects.

Overexpression of puc^Scer\UAS.cMa driven by Scer\GAL4^en-e16E and Scer\GAL4^ptc-559.1 induces abnormal male terminalia rotation and genital arch defects.

(Rousset et al., 2010)

Wing imaginal discs expressing puc^Scer\UAS.cMa under the control of Scer\GAL4^Bx-MS1096-KE are reduced in size compared to controls.

(Rodahl et al., 2009)

Expression of puc^Scer\UAS.cMa under the control of Scer\GAL4^hs.PU using heat shock during 10.5 to 11.5 AEL results in left-right asymmetry defects in the anterior midgut, with a number of embryos showing inversion of the normal asymmetry. Overexpression using heat shock during 4.5 to 5.5 AEL has does not induce defects in anterior midgut left-right asymmetry.

(Taniguchi et al., 2007)

Expression of puc^Scer\UAS.cMa in the developing retina under the control of Scer\GAL4^GMR.PF results in a few mild R axon misrouting defects.

(Sato et al., 2006)

Expression of puc^Scer\UAS.cMa under the control of Scer\GAL4^ey.PH does not affect eye size.

(Singh et al., 2006)

Expression of puc^Scer\UAS.cMa in the posterior compartment of the wing disc, driven by Scer\GAL4^en-e16E, prevents normal wound healing in the posterior part of the disc in around 60% of cases. Wound healing in the anterior part of the disc, where puc^Scer\UAS.cMa is not expressed, is unaffected.

(Bosch et al., 2005)

Overexpression of puc^Scer\UAS.cMa in the notum of wing imaginal discs under the regulation of Scer\GAL4^ap-md544 induces a marked cleft in the thorax.

(Cha et al., 2005)

When puc^Scer\UAS.cMa is driven by Scer\GAL4^e22c or Scer\GAL4^69B a strong dorsal closure defect is observed.

(Galko and Krasnow, 2004)

Expression of puc driven by Scer\GAL4^dpp.blk1 and Scer\GAL4^en-e16E causes rotation of the male terminalia and dorsal split. Spermiduct and sperm pump are misrotated.

(Macias et al., 2004)

Shortly after pupariation begins in wild-type flies, the wing discs move so that their peripodial side is in apposition with the larval epidermis. This fails completely in puc^Scer\UAS.cMa; Scer\GAL4^Act5C.PI flies. (Scer\GAL4^Act5C.PI induced from Scer\GAL4^{Scer\FRT.Act5C} at 48-60 hours before puparium formation). Less severe phenotypes are seen in animals which also heterozygous for puc^E69. In many cases disc eversion and spreading fails. In the least sever cases, eversion and spreading occurs normally but fusion to adjacent discs fails.

(Pastor-Pareja et al., 2004)

Expression of puc^Scer\UAS.cMa under the control of Scer\GAL4^hs.2sev does not affect eye development. Expression of puc^Scer\UAS.cMa under the control of Scer\GAL4^en-GAL4-54 does not affect wing development. Expression of puc^Scer\UAS.cMa under the control of Scer\GAL4^69B causes a dorsal closure defect in embryos.

(Rintelen et al., 2003)

Expression of puc^Scer\UAS.cMa under the control of Scer\GAL4^elav-C155 results in a 25-30% decrease in EJC amplitude (synaptic strength) and bouton number at the larval neuromuscular junction.

(Sanyal et al., 2002)

Expression of puc^Scer\UAS.cMa under the control of Scer\GAL4^hs.PB using heat shock results in variably short eggs with dorsal appendage defects within 24 hours of expression. Expression of puc^Scer\UAS.cMa in large clones in the follicle cells under the control of Scer\GAL4^Act5C.PP results in defective egg chambers composed of a significant mass of nurse cell material connected to a small chorion encased egg.

(Dobens et al., 2001)

Expression of puc^Scer\UAS.cMa, when driven by Scer\GAL4^pnr-MD237 leads to a mild thorax closure defect in adult flies.

(Mihaly et al., 2001)

Expression of puc^Scer\UAS.cMa in the posterior region of the follicular epithelium under the control of Scer\GAL4^E4 has no effect on egg morphology or the embryo. Expression of puc^Scer\UAS.cMa in the anterior region of the main body follicle cells under the control of Scer\GAL4^55B results in a significant alteration in dorsal appendage shape and size. Micropyles are usually very reduced in size. Expression of puc^Scer\UAS.cMa in the follicle cells using either Scer\GAL4^T155 or Scer\GAL4^CY2 results in dorsal appendage and micropyle defects. Expression of puc^Scer\UAS.cMa in the anterior region of the main body follicle cells under the control of Scer\GAL4^55B results in a significant alteration in dorsal appendage shape and size. Micropyles are usually very reduced in size. Expression of puc^Scer\UAS.cMa using Scer\GAL4^slbo.2.6 results in eggs with strongly shortened micropyles but normal dorsal appendages.

(Suzanne et al., 2001)

The expression of puc^Scer\UAS.cMa driven by Scer\GAL4^LE results in adults with a mild thorax cleft phenotype.

(Martin-Blanco et al., 2000)

When expression is driven by Scer\GAL4^{arm.T:Hsim\VP16} the dorsal surface of the embryos are completely open.

(McEwen et al., 2000)

When expression is driven by Scer\GAL4^hs.2sev the eyes of the flies can be mildly or occasionally very rough. Eyes show tissue polarity defects in tangential sections.

(Weber et al., 2000)

Expression of puc^Scer\UAS.cMa under the control of Scer\GAL4^pnr-MD237 or Scer\GAL4^ap-md544 results in the appearance of a cleft in the thorax.

(Zeitlinger and Bohmann, 1999)

Embryos expressing puc^Scer\UAS.cMa under the control of Scer\GAL4^hs.PB fail to achieve dorsal closure and have a large dorsal opening if they are heat shocked between 4 and 5 hours after egg laying (AEL). Most embryos heat shocked between 5 and 7 hours AEL have a dorsal hole or a phenotype similar to puc loss of function alleles. Embryos heat shocked after 7 hours AEL have a puc loss of function phenotype. Dorsal epidermal cells of embryos expressing puc^Scer\UAS.cMa under the control of Scer\GAL4^arm.PS do not change their shape during the time of dorsal closure, in contrast to wild-type.

(Martin-Blanco et al., 1998)

Flies expressing puc^Scer\UAS.cMa in the scutellum under the control of Scer\GAL4^455.2 have ectopic macrochaetae in the scutellum. Wing vein pattern is normal in these flies. Flies expressing puc^Scer\UAS.cMa in the eye under the control of Scer\GAL4^GMR.PF lack many accessory cells. Most ommatidia have the normal pattern of photoreceptors cells.

(Martin-Blanco, 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^en-e16E, puc^UAS.cMa has visible phenotype, enhanceable by scaf^UAS.cRa/Scer\GAL4^en-e16E

(Rousset et al., 2010)

Suppressed by

Statement

Reference

Scer\GAL4^elav-C155, puc^UAS.cMa has abnormal neuroanatomy phenotype, suppressible by bsk^UAS.cBa

(Sanyal et al., 2002)

Scer\GAL4^elav-C155, puc^UAS.cMa has abnormal neurophysiology phenotype, suppressible by bsk^UAS.cBa

(Sanyal et al., 2002)

Enhancer of

Statement

Reference

puc^UAS.cMa/Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Scer\GAL4^GMR.PF, cindr^{RNAi.PC.PD.UAS}

(Ketosugbo et al., 2017)

puc^UAS.cMa, Scer\GAL4^GMR.PF is an enhancer of visible | adult stage phenotype of HAdV-C\E4orf4^UAS.cPa, Scer\GAL4^GMR.PF

(Pechkovsky et al., 2013)

puc^UAS.cMa, Scer\GAL4^GMR.PF is an enhancer of abnormal size | adult stage phenotype of HAdV-C\E4orf4^UAS.cPa, Scer\GAL4^GMR.PF

(Pechkovsky et al., 2013)

Scer\GAL4^nub-AC-62/puc^UAS.cMa is an enhancer of abnormal size phenotype of Scer\GAL4^nub-AC-62, hppy^UAS.cMa

(Resnik-Docampo and de Celis, 2011)

NOT Enhancer of

Statement

Reference

puc^UAS.cMa, Scer\GAL4^GMR.long is a non-enhancer of visible | adult stage phenotype of Hsap\APP^2xAPP.SP.UAS, Mnat9^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^GMR.long

(Deshpande et al., 2023)

puc^UAS.cMa, Scer\GAL4^GMR.PU is a non-enhancer of visible | adult stage | progressive phenotype of Hsap\ATXN3^{fl.Q78.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Vinatier et al., 2015)

puc^UAS.cMa, Scer\GAL4^GMR.PU is a non-enhancer of abnormal eye color | progressive phenotype of Hsap\ATXN3^{fl.Q78.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Vinatier et al., 2015)

puc^UAS.cMa, Scer\GAL4^GMR.PF is a non-enhancer of visible phenotype of Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Suppressor of

Statement

Reference

puc^UAS.cMa, Scer\GAL4^GMR.long is a suppressor | partially of visible | adult stage phenotype of Hsap\APP^2xAPP.SP.UAS, Scer\GAL4^GMR.long

(Deshpande et al., 2023)

puc^UAS.cMa, Scer\GAL4^GMR.long is a suppressor | partially of decreased size | adult stage phenotype of Hsap\APP^2xAPP.SP.UAS, Scer\GAL4^GMR.long

(Deshpande et al., 2023)

puc^UAS.cMa, Scer\GAL4^GMR.long is a suppressor | partially of visible | adult stage phenotype of Hsap\APP^2xAPP.SP.UAS, Mnat9^KK109382, Scer\GAL4^GMR.long

(Deshpande et al., 2023)

puc^UAS.cMa, Scer\GAL4^GMR.long is a suppressor | partially of decreased size | adult stage phenotype of Hsap\APP^2xAPP.SP.UAS, Mnat9^KK109382, Scer\GAL4^GMR.long

(Deshpande et al., 2023)

puc^UAS.cMa, Scer\GAL4^GMR.long is a suppressor | partially of increased cell death | larval stage phenotype of Hsap\APP^2xAPP.SP.UAS, Scer\GAL4^GMR.long

(Deshpande et al., 2023)

puc^UAS.cMa, Scer\GAL4^GMR.long is a suppressor | partially of increased cell death | larval stage phenotype of Hsap\APP^2xAPP.SP.UAS, Mnat9^KK109382, Scer\GAL4^GMR.long

(Deshpande et al., 2023)

puc^UAS.cMa, Scer\GAL4^Act5C.PI is a suppressor of neoplasia | larval stage | somatic clone - tissue specific phenotype of Ras85D^V12.UAS, Scer\GAL4^Act5C.PI, l(2)gl⁴

(Ding et al., 2022)

Scer\GAL4^ptc-559.1/puc^UAS.cMa is a suppressor | partially of abnormal cell migration | third instar larval stage phenotype of Scer\GAL4^ptc-559.1, scrib^GD11666

(Ding et al., 2022, Zhang et al., 2019)

puc^UAS.cMa, Scer\GAL4^ap-md544 is a suppressor of abnormal developmental rate phenotype of BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544

(Romão et al., 2021)

puc^UAS.cMa, Scer\GAL4^e22c is a suppressor of increased size | larval stage phenotype of BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^e22c

(Romão et al., 2021)

Scer\GAL4^nub.PU/puc^UAS.cMa is a suppressor | partially of increased cell death | larval stage phenotype of RpS3^Plac92, yki^B5

(Wada et al., 2021)

Scer\GAL4^nub.PU/puc^UAS.cMa is a suppressor | partially of visible | adult stage phenotype of RpS3^Plac92, yki^B5

(Wada et al., 2021)

Scer\GAL4^nub.PU/puc^UAS.cMa is a suppressor | partially of decreased size | adult stage phenotype of RpS3^Plac92, yki^B5

(Wada et al., 2021)

puc^UAS.cMa, Scer\GAL4^Act.PU is a suppressor of neoplasia | somatic clone | larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^Act.PU, l(2)gl⁴

(Zhang et al., 2019)

puc^UAS.cMa, Scer\GAL4^Act.PU is a suppressor of abnormal cell migration | somatic clone | larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^Act.PU, l(2)gl⁴

(Zhang et al., 2019)

puc^UAS.cMa, Scer\GAL4^Act.PU is a suppressor | partially of increased mortality during development | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^Act.PU, l(2)gl⁴

(Zhang et al., 2019)

puc^UAS.cMa, Scer\GAL4^nub.PU is a suppressor | partially of visible | adult stage phenotype of His1^NIG.31617R, Scer\GAL4^nub.PU

(Bayona-Feliu et al., 2017)

puc^UAS.cMa, Scer\GAL4^nub.PU is a suppressor | partially of abnormal size | adult stage phenotype of His1^NIG.31617R, Scer\GAL4^nub.PU

(Bayona-Feliu et al., 2017)

puc^UAS.cMa, Scer\GAL4^nub.PU is a suppressor of increased cell death | third instar larval stage phenotype of His1^NIG.31617R, Scer\GAL4^nub.PU

(Bayona-Feliu et al., 2017)

puc^UAS.cMa/Scer\GAL4^ptc.PU is a suppressor of visible | adult stage phenotype of Scer\GAL4^ptc.PU, fmt^GD6928

(Ma et al., 2017)

puc^UAS.cMa, Scer\GAL4^Act.PU is a suppressor of neoplasia | somatic clone | third instar larval stage phenotype of BacA\p35^UAS.cHa, Scer\GAL4^Act.PU, Snr1^HMS00363

(Xie et al., 2017)

puc^UAS.cMa/Scer\GAL4^ey.PH is a suppressor of increased cell death | larval stage phenotype of Scer\GAL4^e22c, rod^GD8768

(Clemente-Ruiz et al., 2016)

puc^UAS.cMa, lic^RNAi.UAS.cUa, Scer\GAL4^ey.PH is a suppressor of increased cell death | larval stage phenotype of Scer\GAL4^e22c, rod^GD8768

(Clemente-Ruiz et al., 2016)

puc^UAS.cMa/Scer\GAL4^e22c is a suppressor of increased cell death | male limited | larval stage phenotype of Scer\GAL4^e22c, msl-1^RNAi.UAS.cUa

(Clemente-Ruiz et al., 2016)

Scer\GAL4^bun-GSG5961, puc^UAS.cMa, Scer\GAL4^GSG5966 is a suppressor | RU486 conditional of increased cell number | somatic clone phenotype of Apc2^g10, Apc^Q8

(Suijkerbuijk et al., 2016)

Scer\GAL4^bun-GSG5961, puc^UAS.cMa, Scer\GAL4^GSG5966 is a suppressor | RU486 conditional of decreased cell number | somatic clone | cell non-autonomous phenotype of Apc2^g10, Apc^Q8

(Suijkerbuijk et al., 2016)

puc^UAS.cMa/Scer\GAL4^Tub.PU is a suppressor | somatic clone of increased cell number | somatic clone phenotype of Apc2^g10, Apc^Q8

(Suijkerbuijk et al., 2016)

puc^UAS.cMa/Scer\GAL4^GSG2326 is a suppressor | cell non-autonomous of increased cell number | somatic clone phenotype of Apc2^g10, Apc^Q8

(Suijkerbuijk et al., 2016)

puc^UAS.cMa/Scer\GAL4^rn-GAL4-5 is a suppressor of neoplasia phenotype of Scer\GAL4^rn-GAL4-5, crb^intra.UAS

(Andersen et al., 2015)

puc^UAS.cMa, Scer\GAL4^salm.EPv is a suppressor of neoplasia | third instar larval stage phenotype of Rab5^GD10492, Scer\GAL4^salm.EPv

(Ballesteros-Arias et al., 2014)

puc^UAS.cMa, Scer\GAL4^FRT.Act5C is a suppressor of neoplasia | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^FRT.Act5C, l(2)gl⁴

(Ma et al., 2014)

puc^UAS.cMa, Scer\GAL4^Bx-MS1096 is a suppressor of visible phenotype of Daxx^EY09290, Scer\GAL4^Bx-MS1096

(Hwang et al., 2013)

puc^UAS.cMa, Scer\GAL4^FRT.Act5C is a suppressor of lethal - all die during larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^FRT.Act5C

(Ma et al., 2013)

puc^UAS.cMa, Scer\GAL4^FRT.Act5C is a suppressor of increased cell growth rate phenotype of Ras85D^V12.UAS, Scer\GAL4^FRT.Act5C, l(2)gl⁴

(Ma et al., 2013)

puc^UAS.cMa, Scer\GAL4^FRT.Act5C is a suppressor of abnormal neuroanatomy phenotype of Ras85D^V12.UAS, Scer\GAL4^FRT.Act5C, l(2)gl⁴

(Ma et al., 2013)

puc^UAS.cMa, Scer\GAL4^FRT.Act5C is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^FRT.Act5C, l(2)gl⁴

(Ma et al., 2013)

Scer\GAL4^FRT.Act5C/puc^UAS.cMa is a suppressor of lethal - all die during larval stage phenotype of Scer\GAL4^FRT.Act5C, l(2)gl⁴

(Ma et al., 2013)

puc^UAS.cMa, Scer\GAL4^GMR.PF is a suppressor of increased cell growth rate phenotype of Ras85D^V12.UAS, Scer\GAL4^GMR.PF, l(2)gl⁴

(Ma et al., 2013)

puc^UAS.cMa, Scer\GAL4^GMR.PF is a suppressor of abnormal neuroanatomy phenotype of Ras85D^V12.UAS, Scer\GAL4^GMR.PF, l(2)gl⁴

(Ma et al., 2013)

puc^UAS.cMa, Scer\GAL4^GMR.PF is a suppressor of increased body size phenotype of Ras85D^V12.UAS, Scer\GAL4^GMR.PF, l(2)gl⁴

(Ma et al., 2013)

puc^UAS.cMa, Scer\GAL4^GMR.PF is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^GMR.PF, l(2)gl⁴

(Ma et al., 2013)

puc^UAS.cMa, Scer\GAL4^rn-GAL4-5 is a suppressor of abnormal developmental rate phenotype of RpL7^GD11462, Scer\GAL4^rn-GAL4-5

(Colombani et al., 2012)

puc^UAS.cMa/Scer\GAL4^GMR.PF is a suppressor of increased cell death phenotype of Scer\GAL4^GMR.PF, egr^UAS.cIa

(Ma et al., 2012)

Scer\GAL4^nub-AC-62/puc^UAS.cMa is a suppressor of increased cell death | cell autonomous phenotype of Scer\GAL4^nub-AC-62, hppy^UAS.cMa

(Resnik-Docampo and de Celis, 2011)

puc^UAS.cMa/Scer\GAL4^hh-nd271 is a suppressor of increased cell death phenotype of Scer\GAL4^hh-nd271, nab^EP-nd642

(Suissa et al., 2011)

puc^UAS.cMa is a suppressor of increased cell growth rate | somatic clone | cell non-autonomous phenotype of Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642

(Suissa et al., 2011)

puc^UAS.cMa, Scer\GAL4^GMR.PU is a suppressor of increased cell death phenotype of Hsap\APP^{Aβ42.UAS.cUa}, Scer\GAL4^GMR.PU

(Tare et al., 2011)

puc^UAS.cMa, Scer\GAL4^GMR.PU is a suppressor of abnormal neuroanatomy | progressive phenotype of Hsap\APP^{Aβ42.UAS.cUa}, Scer\GAL4^GMR.PU

(Tare et al., 2011)

puc^UAS.cMa/Scer\GAL4^Tub.PU is a suppressor of increased cell death | somatic clone phenotype of l(2)gl⁴

(Tamori et al., 2010)

puc^UAS.cMa/Scer\GAL4^Tub.PU is a suppressor | somatic clone of increased cell death | somatic clone phenotype of mahj¹

(Tamori et al., 2010)

puc^UAS.cMa, Scer\GAL4^GMR.PF is a suppressor of visible phenotype of Rab11^N124I.UAS, Scer\GAL4^GMR.PF

(Tiwari and Roy, 2009)

puc^UAS.cMa, Scer\GAL4^GMR.PF is a suppressor | partially of visible phenotype of Rab11^RNAi.UAS.WIZ, Scer\GAL4^GMR.PF

(Tiwari and Roy, 2009)

puc^UAS.cMa/Scer\GAL4^GMR.PU is a suppressor of visible phenotype of Scer\GAL4^GMR.PU, Sirt1^UAS.cGa

(Griswold et al., 2008)

puc^UAS.cMa/Scer\GAL4^GMR.PU is a suppressor of abnormal eye color phenotype of Scer\GAL4^GMR.PU, Sirt1^UAS.cGa

(Griswold et al., 2008)

puc^UAS.cMa/BacA\p35^UAS.cHa, Scer\GAL4^unspecified is a suppressor | partially of abnormal size phenotype of Scer\GAL4^unspecified, vg^UAS.cKa

(Baena-Lopez and Garcia-Bellido, 2006)

scrib¹, Scer\GAL4^Act5C.PI, puc^UAS.cMa is a suppressor of lethal | pupal stage phenotype of Ras85D^V12.UAS

(Uhlirova and Bohmann, 2006)

puc^UAS.cMa, Scer\GAL4^Act5C.PI is a suppressor | partially of neoplasia | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^Act5C.PI, scrib¹

(Uhlirova and Bohmann, 2006)

puc^UAS.cMa, Scer\GAL4^Act5C.PI is a suppressor of lethal | somatic clone | third instar larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^Act5C.PI, scrib¹

(Uhlirova and Bohmann, 2006)

puc^UAS.cMa is a suppressor of increased cell death phenotype of Csk^RNAi.UAS, Scer\GAL4^ptc-559.1

(Vidal et al., 2006)

puc^UAS.cMa is a suppressor of increased cell death phenotype of Csk^RNAi.UAS, Scer\GAL4^sd-SG29.1

(Vidal et al., 2006)

Scer\GAL4^αTub84B.PBb/puc^UAS.cMa is a suppressor of increased cell death | somatic clone | cell non-autonomous phenotype of Myc^αTub84B.PBb

(Moreno and Basler, 2004)

puc^UAS.cMa is a suppressor of hyperplasia | somatic clone phenotype of BacA\p35^UAS.cHa, Scer\GAL4^αTub84B.PZ, hid^UAS.cZa

(Ryoo et al., 2004)

puc^UAS.cMa is a suppressor of hyperplasia | somatic clone phenotype of BacA\p35^UAS.cHa, Scer\GAL4^αTub84B.PZ, rpr^UAS.cZa

(Ryoo et al., 2004)

puc^UAS.cMa/Scer\GAL4^αTub84B.PL is a suppressor of abnormal cell growth | somatic clone phenotype of arr²

(Giraldez and Cohen, 2003)

puc^UAS.cMa/Scer\GAL4^GMR.PF is a suppressor of increased cell death phenotype of Scer\GAL4^GMR.PF, egr^UAS.cMa

(Moreno et al., 2002)

puc^UAS.cMa is a suppressor of increased cell death phenotype of Scer\GAL4^C-765, egr^UAS.cMa

(Moreno et al., 2002)

Scer\GAL4^Ubx.PdC/puc^UAS.cMa is a suppressor of increased cell death phenotype of Scer\GAL4^Ubx.PdC, egr^UAS.cMa

(Moreno et al., 2002)

Scer\GAL4^Ubx.PdC/puc^UAS.cMa is a suppressor of cell lethal phenotype of Scer\GAL4^Ubx.PdC, brk^UAS.cJa

(Moreno et al., 2002)

puc^UAS.cMa/Scer\GAL4^455.2 is a suppressor of visible phenotype of Scer\GAL4^455.2, rl^Sem.MB.UAS

(Martin-Blanco, 1998)

NOT Suppressor of

Statement

Reference

Scer\GAL4^hh.PU/puc^UAS.cMa is a non-suppressor of increased cell death | larval stage phenotype of Scer\GAL4^hh.PU, Spyo\Cas9^UAS.P2, wg^{UAS.wg+intergenic-1.pCFD6}

(Ewen-Campen and Perrimon, 2024)

puc^UAS.cMa, Scer\GAL4^GMR.long is a non-suppressor of visible | adult stage phenotype of Hsap\APP^2xAPP.SP.UAS, Mnat9^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^GMR.long

(Deshpande et al., 2023)

puc^UAS.cMa/Scer\GAL4^Tub.PU is a non-suppressor of increased cell death | somatic clone | third instar larval stage phenotype of Vps4^3B1

(Legent et al., 2015)

puc^UAS.cMa, Scer\GAL4^GMR.PU is a non-suppressor of visible | adult stage | progressive phenotype of Hsap\ATXN3^{fl.Q78.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Vinatier et al., 2015)

puc^UAS.cMa, Scer\GAL4^GMR.PU is a non-suppressor of abnormal eye color | progressive phenotype of Hsap\ATXN3^{fl.Q78.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Vinatier et al., 2015)

puc^UAS.cMa/Scer\GAL4^GMR.PF is a non-suppressor of increased cell death phenotype of Scer\GAL4^GMR.PF, nopo^UAS.cUa

(Ma et al., 2012)

puc^UAS.cMa, Scer\GAL4^GMR.PF is a non-suppressor of visible phenotype of Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

puc^UAS.cMa, Scer\GAL4^GMR.PF is a non-suppressor of increased cell death phenotype of Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^GMR.PF

(Moreno et al., 2002)

Other

Statement

Reference

Hsap\APP^2xAPP.SP.UAS, Mnat9^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^GMR.long, puc^UAS.cMa has increased cell death | larval stage phenotype

(Deshpande et al., 2023)

Scer\GAL4^Act5C.PP, egr^{ecto-60.UAS.Tag:HA,Tag:FLAG}, puc^UAS.cMa has increased cell death | somatic clone phenotype

(Narasimamurthy et al., 2009)

Scer\GAL4^Tub.PU, Vps25^N55, puc^UAS.cMa has neoplasia | somatic clone | third instar larval stage phenotype

(Herz et al., 2006)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^en-e16E, puc^UAS.cMa has male terminalia phenotype, enhanceable by scaf^UAS.cRa/Scer\GAL4^en-e16E

(Rousset et al., 2010)

Scer\GAL4^ap-md544, puc^UAS.cMa has adult thorax phenotype, enhanceable by Scer\GAL4^ap-md544/park[+]/park^UAS.Tag:MYC

(Cha et al., 2005)

Scer\GAL4^ap-md544, puc^UAS.cMa has mesothoracic cleft | ectopic phenotype, enhanceable by Scer\GAL4^ap-md544/park[+]/park^UAS.Tag:MYC

(Cha et al., 2005)

Suppressed by

Statement

Reference

Scer\GAL4^elav-C155, puc^UAS.cMa has neuromuscular junction | larval stage phenotype, suppressible by bsk^UAS.cBa

(Sanyal et al., 2002)

Scer\GAL4^elav-C155, puc^UAS.cMa has bouton phenotype, suppressible by bsk^UAS.cBa

(Sanyal et al., 2002)

Enhancer of

Statement

Reference

puc^UAS.cMa/Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, cindr^{RNAi.PC.PD.UAS}

(Ketosugbo et al., 2017)

puc^UAS.cMa, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of HAdV-C\E4orf4^UAS.cPa, Scer\GAL4^GMR.PF

(Pechkovsky et al., 2013)

Scer\GAL4^ap-md544/puc^UAS.cMa is an enhancer of adult thorax phenotype of Scer\GAL4^ap-md544, park^UAS.Tag:MYC

(Cha et al., 2005)

Scer\GAL4^ap-md544/puc^UAS.cMa is an enhancer of mesothoracic cleft | ectopic phenotype of Scer\GAL4^ap-md544, park^UAS.Tag:MYC

(Cha et al., 2005)

NOT Enhancer of

Statement

Reference

puc^UAS.cMa, Scer\GAL4^GMR.long is a non-enhancer of eye phenotype of Hsap\APP^2xAPP.SP.UAS, Mnat9^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^GMR.long

(Deshpande et al., 2023)

puc^UAS.cMa, Scer\GAL4^GMR.PU is a non-enhancer of eye | progressive phenotype of Hsap\ATXN3^{fl.Q78.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Vinatier et al., 2015)

puc^UAS.cMa, Scer\GAL4^GMR.PF is a non-enhancer of eye phenotype of Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Suppressor of

Statement

Reference

puc^UAS.cMa, Scer\GAL4^GMR.long is a suppressor | partially of eye phenotype of Hsap\APP^2xAPP.SP.UAS, Scer\GAL4^GMR.long

(Deshpande et al., 2023)

puc^UAS.cMa, Scer\GAL4^GMR.long is a suppressor | partially of eye phenotype of Hsap\APP^2xAPP.SP.UAS, Mnat9^KK109382, Scer\GAL4^GMR.long

(Deshpande et al., 2023)

puc^UAS.cMa, Scer\GAL4^GMR.long is a suppressor | partially of eye disc | larval stage phenotype of Hsap\APP^2xAPP.SP.UAS, Scer\GAL4^GMR.long

(Deshpande et al., 2023)

puc^UAS.cMa, Scer\GAL4^GMR.long is a suppressor | partially of eye disc | larval stage phenotype of Hsap\APP^2xAPP.SP.UAS, Mnat9^KK109382, Scer\GAL4^GMR.long

(Deshpande et al., 2023)

puc^UAS.cMa, Scer\GAL4^Act5C.PI is a suppressor of larval ventral nerve cord | somatic clone - tissue specific phenotype of Ras85D^V12.UAS, Scer\GAL4^Act5C.PI, l(2)gl⁴

(Ding et al., 2022)

puc^UAS.cMa, Scer\GAL4^Act5C.PI is a suppressor of eye-antennal disc | somatic clone - tissue specific phenotype of Ras85D^V12.UAS, Scer\GAL4^Act5C.PI, l(2)gl⁴

(Ding et al., 2022)

Scer\GAL4^ptc-559.1/puc^UAS.cMa is a suppressor | partially of anterior-posterior compartment boundary of the wing disc | third instar larval stage phenotype of Scer\GAL4^ptc-559.1, scrib^GD11666

(Ding et al., 2022, Zhang et al., 2019)

puc^UAS.cMa, Scer\GAL4^e22c is a suppressor of wing disc | larval stage phenotype of BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^e22c

(Romão et al., 2021)

Scer\GAL4^nub.PU/puc^UAS.cMa is a suppressor | partially of wing phenotype of RpS3^Plac92, yki^B5

(Wada et al., 2021)

Scer\GAL4^nub.PU/puc^UAS.cMa is a suppressor | partially of wing disc | larval stage phenotype of RpS3^Plac92, yki^B5

(Wada et al., 2021)

puc^UAS.cMa, Scer\GAL4^Act.PU is a suppressor of larval ventral nerve cord | somatic clone | larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^Act.PU, l(2)gl⁴

(Zhang et al., 2019)

puc^UAS.cMa, Scer\GAL4^Act.PU is a suppressor of eye-antennal disc | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^Act.PU, l(2)gl⁴

(Zhang et al., 2019)

puc^UAS.cMa, Scer\GAL4^nub.PU is a suppressor | partially of wing phenotype of His1^NIG.31617R, Scer\GAL4^nub.PU

(Bayona-Feliu et al., 2017)

puc^UAS.cMa, Scer\GAL4^nub.PU is a suppressor of wing disc | third instar larval stage phenotype of His1^NIG.31617R, Scer\GAL4^nub.PU

(Bayona-Feliu et al., 2017)

puc^UAS.cMa/Scer\GAL4^ptc.PU is a suppressor of anterior crossvein phenotype of Scer\GAL4^ptc.PU, fmt^GD6928

(Ma et al., 2017)

puc^UAS.cMa, Scer\GAL4^Act.PU is a suppressor of wing disc | somatic clone | third instar larval stage phenotype of BacA\p35^UAS.cHa, Scer\GAL4^Act.PU, Snr1^HMS00363

(Xie et al., 2017)

puc^UAS.cMa/Scer\GAL4^ey.PH is a suppressor of wing disc posterior compartment phenotype of Scer\GAL4^e22c, rod^GD8768

(Clemente-Ruiz et al., 2016)

puc^UAS.cMa, lic^RNAi.UAS.cUa, Scer\GAL4^ey.PH is a suppressor of wing disc posterior compartment phenotype of Scer\GAL4^e22c, rod^GD8768

(Clemente-Ruiz et al., 2016)

puc^UAS.cMa/Scer\GAL4^e22c is a suppressor of wing disc posterior compartment | male limited phenotype of Scer\GAL4^e22c, msl-1^RNAi.UAS.cUa

(Clemente-Ruiz et al., 2016)

puc^UAS.cMa/Scer\GAL4^Tub.PU is a suppressor | somatic clone of intestinal stem cell of posterior adult midgut epithelium | somatic clone phenotype of Apc2^g10, Apc^Q8

(Suijkerbuijk et al., 2016)

Scer\GAL4^bun-GSG5961, puc^UAS.cMa, Scer\GAL4^GSG5966 is a suppressor | RU486 conditional of intestinal stem cell of posterior adult midgut epithelium | somatic clone phenotype of Apc2^g10, Apc^Q8

(Suijkerbuijk et al., 2016)

Scer\GAL4^bun-GSG5961, puc^UAS.cMa, Scer\GAL4^GSG5966 is a suppressor | RU486 conditional of intestinal stem cell of posterior adult midgut epithelium | somatic clone | cell non-autonomous phenotype of Apc2^g10, Apc^Q8

(Suijkerbuijk et al., 2016)

puc^UAS.cMa/Scer\GAL4^GSG2326 is a suppressor | cell non-autonomous of intestinal stem cell of posterior adult midgut epithelium | somatic clone phenotype of Apc2^g10, Apc^Q8

(Suijkerbuijk et al., 2016)

puc^UAS.cMa/Scer\GAL4^GMR.PU is a suppressor | partially of eye phenotype of Scer\GAL4^GMR.PU, egr^{ecto-60.UAS.Tag:HA,Tag:FLAG}

(Andersen et al., 2015)

puc^UAS.cMa/Scer\GAL4^GMR.PU is a suppressor of eye phenotype of Scer\GAL4^GMR.PU, egr^UAS.cMa

(Andersen et al., 2015, Narasimamurthy et al., 2009)

puc^UAS.cMa, Scer\GAL4^salm.EPv is a suppressor of wing pouch | third instar larval stage phenotype of Rab5^GD10492, Scer\GAL4^salm.EPv

(Ballesteros-Arias et al., 2014)

puc^UAS.cMa, Scer\GAL4^Bx-MS1096 is a suppressor of wing phenotype of Daxx^EY09290, Scer\GAL4^Bx-MS1096

(Hwang et al., 2013)

puc^UAS.cMa, Scer\GAL4^FRT.Act5C is a suppressor of larval ventral nerve cord phenotype of Ras85D^V12.UAS, Scer\GAL4^FRT.Act5C, l(2)gl⁴

(Ma et al., 2013)

puc^UAS.cMa, Scer\GAL4^GMR.PF is a suppressor of larval ventral nerve cord phenotype of Ras85D^V12.UAS, Scer\GAL4^GMR.PF, l(2)gl⁴

(Ma et al., 2013)

puc^UAS.cMa, Scer\GAL4^GMR.PF is a suppressor of larva phenotype of Ras85D^V12.UAS, Scer\GAL4^GMR.PF, l(2)gl⁴

(Ma et al., 2013)

Scer\GAL4^ptc-559.1/puc^UAS.cMa is a suppressor of wing disc phenotype of Scer\GAL4^ptc-559.1, Vha44^UAS.Tag:HA

(Petzoldt et al., 2013)

puc^UAS.cMa/Scer\GAL4^rn-GAL4-5 is a suppressor of phenotype of Scer\GAL4^rn-GAL4-5, Syx7^GD2767

(Colombani et al., 2012)

puc^UAS.cMa/Scer\GAL4^GMR.PF is a suppressor of eye phenotype of Scer\GAL4^GMR.PF, egr^UAS.cIa

(Ma et al., 2012)

Scer\GAL4^ptc-559.1/puc^UAS.cMa is a suppressor | partially of wing disc phenotype of Scer\GAL4^ptc-559.1, sds22^GD11788

(Jiang et al., 2011)

puc^UAS.cMa/Scer\GAL4^hh-nd271 is a suppressor of wing disc phenotype of Scer\GAL4^hh-nd271, nab^EP-nd642

(Suissa et al., 2011)

puc^UAS.cMa/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of wing disc | somatic clone | cell non-autonomous phenotype of Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642

(Suissa et al., 2011)

puc^UAS.cMa, Scer\GAL4^GMR.PU is a suppressor of eye phenotype of Hsap\APP^{Aβ42.UAS.cUa}, Scer\GAL4^GMR.PU

(Tare et al., 2011)

puc^UAS.cMa, Scer\GAL4^GMR.PU is a suppressor of eye disc phenotype of Hsap\APP^{Aβ42.UAS.cUa}, Scer\GAL4^GMR.PU

(Tare et al., 2011)

puc^UAS.cMa/Scer\GAL4^Tub.PU is a suppressor of wing disc | somatic clone phenotype of l(2)gl⁴

(Tamori et al., 2010)

puc^UAS.cMa/Scer\GAL4^Tub.PU is a suppressor | partially | somatic clone of wing disc | somatic clone phenotype of mahj¹

(Tamori et al., 2010)

Scer\GAL4^Bx-MS1096-KE/puc^UAS.cMa is a suppressor | partially of actin filament & dorsal mesothoracic disc phenotype of Scer\GAL4^Bx-MS1096-KE, Vps4^{DN.UAS.Tag:HA}

(Rodahl et al., 2009)

puc^UAS.cMa, Scer\GAL4^GMR.PF is a suppressor of eye phenotype of Rab11^N124I.UAS, Scer\GAL4^GMR.PF

(Tiwari and Roy, 2009)

puc^UAS.cMa, Scer\GAL4^GMR.PF is a suppressor | partially of eye phenotype of Rab11^RNAi.UAS.WIZ, Scer\GAL4^GMR.PF

(Tiwari and Roy, 2009)

puc^UAS.cMa/Scer\GAL4^GMR.PU is a suppressor of eye phenotype of Scer\GAL4^GMR.PU, Sirt1^UAS.cGa

(Griswold et al., 2008)

puc^UAS.cMa/Scer\GAL4^αTub84B.PL is a suppressor | partially | somatic clone of wing disc | somatic clone phenotype of vg^null

(Baena-Lopez and Garcia-Bellido, 2006)

puc^UAS.cMa/BacA\p35^UAS.cHa, Scer\GAL4^unspecified is a suppressor | partially of wing phenotype of Scer\GAL4^unspecified, vg^UAS.cKa

(Baena-Lopez and Garcia-Bellido, 2006)

Scer\GAL4^wex1.rev, Scer\GAL4^wex1.for, puc^UAS.cMa is a suppressor of embryo | dorsal closure stage phenotype of FER^gof

(Murray et al., 2006)

Scer\GAL4^wex1.rev, Scer\GAL4^wex1.for, puc^UAS.cMa is a suppressor of embryonic leading edge cell & actomyosin phenotype of FER^gof

(Murray et al., 2006)

Scer\GAL4^wex1.rev, Scer\GAL4^wex1.for, puc^UAS.cMa is a suppressor of embryonic leading edge cell & filopodium phenotype of FER^gof

(Murray et al., 2006)

Scer\GAL4^wex1.rev, Scer\GAL4^wex1.for, puc^UAS.cMa is a suppressor of ventral midline of embryo phenotype of FER^gof

(Murray et al., 2006)

puc^UAS.cMa/Scer\GAL4^ey.PH is a suppressor of eye disc | ventral phenotype of L²

(Singh et al., 2006)

puc^UAS.cMa/Scer\GAL4^ey.PH is a suppressor of eye | ventral phenotype of L²

(Singh et al., 2006)

puc^UAS.cMa, Scer\GAL4^ey.PH, BacA\p35^UAS.cHa is a suppressor of eye | ventral phenotype of L²

(Singh et al., 2006)

Scer\GAL4^Act5C.PI/puc^UAS.cMa is a suppressor of eye-antennal disc | somatic clone phenotype of Ras85D^V12.UAS

(Uhlirova and Bohmann, 2006)

puc^UAS.cMa, Scer\GAL4^Act5C.PI is a suppressor of larval ventral nerve cord | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^Act5C.PI, scrib¹

(Uhlirova and Bohmann, 2006)

puc^UAS.cMa, Scer\GAL4^Act5C.PI is a suppressor of larval brain | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^Act5C.PI, scrib¹

(Uhlirova and Bohmann, 2006)

puc^UAS.cMa is a suppressor of zonula adherens & disc epithelium proper phenotype of Csk^RNAi.UAS, Scer\GAL4^ptc-559.1

(Vidal et al., 2006)

puc^UAS.cMa is a suppressor of wing disc | somatic clone phenotype of BacA\p35^UAS.cHa, Scer\GAL4^αTub84B.PZ, rpr^UAS.cZa

(Ryoo et al., 2004)

Scer\GAL4^nub-AC-62/puc^UAS.cMa is a suppressor of wing disc phenotype of bi^omb-3198

(del Alamo Rodriguez et al., 2004)

puc^UAS.cMa/Scer\GAL4^GMR.PF is a suppressor of eye phenotype of Scer\GAL4^GMR.PF, egr^UAS.cMa

(Moreno et al., 2002)

puc^UAS.cMa is a suppressor of wing phenotype of Scer\GAL4^C-765, egr^UAS.cMa

(Moreno et al., 2002)

Scer\GAL4^Ubx.PdC/puc^UAS.cMa is a suppressor of wing disc phenotype of Scer\GAL4^Ubx.PdC, egr^UAS.cMa

(Moreno et al., 2002)

Scer\GAL4^Ubx.PdC/puc^UAS.cMa is a suppressor of wing disc phenotype of Scer\GAL4^Ubx.PdC, brk^UAS.cJa

(Moreno et al., 2002)

puc^UAS.cMa/Scer\GAL4^455.2 is a suppressor of wing phenotype of Scer\GAL4^455.2, rl^Sem.MB.UAS

(Martin-Blanco, 1998)

puc^UAS.cMa/Scer\GAL4^455.2 is a suppressor of wing vein phenotype of Scer\GAL4^455.2, rl^Sem.MB.UAS

(Martin-Blanco, 1998)

NOT Suppressor of

Statement

Reference

Scer\GAL4^hh.PU/puc^UAS.cMa is a non-suppressor of wing disc posterior compartment | larval stage phenotype of Scer\GAL4^hh.PU, Spyo\Cas9^UAS.P2, wg^{UAS.wg+intergenic-1.pCFD6}

(Ewen-Campen and Perrimon, 2024)

puc^UAS.cMa, Scer\GAL4^GMR.long is a non-suppressor of eye phenotype of Hsap\APP^2xAPP.SP.UAS, Mnat9^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^GMR.long

(Deshpande et al., 2023)

puc^UAS.cMa/Scer\GAL4^Tub.PU is a non-suppressor of eye disc | somatic clone | third instar larval stage phenotype of Vps4^3B1

(Legent et al., 2015)

puc^UAS.cMa, Scer\GAL4^GMR.PU is a non-suppressor of eye | progressive phenotype of Hsap\ATXN3^{fl.Q78.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Vinatier et al., 2015)

puc^UAS.cMa/Scer\GAL4^GMR.PF is a non-suppressor of eye phenotype of Scer\GAL4^GMR.PF, nopo^UAS.cUa

(Ma et al., 2012)

puc^UAS.cMa, Scer\GAL4^GMR.PF is a non-suppressor of eye phenotype of Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Scer\GAL4^nub-AC-62/puc^UAS.cMa is a non-suppressor of wing phenotype of Scer\GAL4^nub-AC-62, brk^UAS.cJa

(Martin et al., 2004)

Scer\GAL4^nub-AC-62/puc^UAS.cMa is a non-suppressor of wing disc phenotype of bi^omb-3198

(del Alamo Rodriguez et al., 2004)

puc^UAS.cMa, Scer\GAL4^GMR.PF is a non-suppressor of eye phenotype of Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^GMR.PF

(Moreno et al., 2002)

Other

Statement

Reference

Hsap\APP^2xAPP.SP.UAS, Mnat9^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^GMR.long, puc^UAS.cMa has eye disc | larval stage phenotype

(Deshpande et al., 2023)

Scer\GAL4^GMR.PU, egr^{ecto-60.UAS.Tag:HA,Tag:FLAG}, puc^UAS.cMa has eye phenotype

(Narasimamurthy et al., 2009)

Scer\GAL4^Bx-MS1096-KE, Vps4^{DN.UAS.Tag:HA}, puc^UAS.cMa has wing disc phenotype

(Rodahl et al., 2009)

Dark^H16, Scer\GAL4^Tub.PU, Vps25^N55, puc^UAS.cMa has eye phenotype

(Herz et al., 2006)

Additional Comments

Genetic Interactions

Statement

Reference

The extensive cell death in the pouch region of wing discs in third instar larvae as well as the small and deformed wings in adults expressing His1:CG31617^NIG.31617R under the control of Scer\GAL4^nub.PU are significantly suppressed by co-expression of puc^Scer\UAS.cMa.

(Bayona-Feliu et al., 2017)

The partial or complete loss of the wing anterior crossvein in flies expressing fmt^GD6928 under the control of Scer\GAL4^ptc.PU is suppressed by co-expression of puc^Scer\UAS.cMa.

(Ma et al., 2017)

Expression of puc^Scer\UAS.cMa under the control of Scer\GAL4^bun-GSG5961 and Scer\GAL4^GSG5966 (along with RU486 to induce expression via the GeneSwitch system) in the gut fully restores growth of wild type clones in the presence of Apc^Q8/Apc^Q8, Apc2^g10/Apc2^g10 mutant clones in the posterior midgut, and suppresses the growth of Apc^Q8/Apc^Q8, Apc2^g10/Apc2^g10 mutant clones. Apc^Q8/Apc^Q8, Apc2^g10/Apc2^g10 mutant clones expressing puc^Scer\UAS.cMa under the control of Scer\GAL4^tub.PU also show suppressed growth. Expression of puc^Scer\UAS.cMa in host tissue only, under the control of Scer\GAL4^GSG2326, severely suppresses growth of Apc^Q8/Apc^Q8, Apc2^g10/Apc2^g10 mutant clones.

(Suijkerbuijk et al., 2016)

Expression of puc^Scer\UAS.cMa under the control of Scer\GAL4^tub.PU does not suppress the photoreceptor differentiation defects or increased cell death seen in Vps4^3B1 mutant eye disc clones.

(Legent et al., 2015)

Co-expression of puc^Scer\UAS.cMa results in suppression of the tumorigenesis observed in the mutant domain in flies expressing Rab5^GD10492 under the control of Scer\GAL4^salm.EPv (in combination with a Gal80[ts] transgene to restrict expression to the third instar larval stage) in the wing pouch.

(Ballesteros-Arias et al., 2014)

Expression of Ras85D^V12.Scer\UAS under the control of Scer\GAL4^{Scer\FRT.Act5C} in l(2)gl⁴ mutant cells in eye-antennal discs using the ey-FLP/MARCM system results in tumor-like growth with invasive migration into the ventral nerve cord of the CNS. The growth and invasion of these tumors is dramatically suppressed upon co-expression of puc^Scer\UAS.cMa.

(Ma et al., 2014)

The reduced wing phenotype caused by expression of DLP^EY09290 under the control of Scer\GAL4^Bx-MS1096 is suppressed by co-expression of puc^Scer\UAS.cMa.

(Hwang et al., 2013)

Blocking JNK signaling by expression of puc^Scer\UAS.cMa dramatically suppresses the growth and invasion behaviours of Ras85D^V12.Scer\UAS/l(2)gl⁴ tumours.

(Ma et al., 2013)

Inactivation of JNK signaling, through the expression of puc^Scer\UAS.cMa, dramatically suppresses the Ras85D^V12.Scer\UAS/l(2)gl⁴ mutant tumour growth and invasion, and rescues animals to pupal stage.

(Ma et al., 2013)

Co-expression of puc^Scer\UAS.cMa suppresses the cell invasion phenotype (migration into the posterior compartment) seen in anterior cells in the wing disc expressing Vha44^{Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^ptc-559.1.

(Petzoldt et al., 2013)

Coexpression of puc^Scer\UAS.cMa rescues the delay at pupariation of Scer\GAL4^rn-GAL4-5, Syx7^GD2767 animals.

Coexpression of puc^Scer\UAS.cMa rescues the delay at pupariation of Scer\GAL4^rn-GAL4-5, RpL7^GD11462 animals.

(Colombani et al., 2012)

Co-expression of puc^Scer\UAS.cMa does not suppress the small, rough eye phenotype found upon expression of nopo^Scer\UAS.cUa under the control of Scer\GAL4^GMR.PF.

egr^Scer\UAS.cIa-induced cell death is partially suppressed by co-expression of puc^Scer\UAS.cMa, under the control of Scer\GAL4^GMR.PF.

(Ma et al., 2012)

The cell invasion phenotype seen in cells expressing sds22^GD11788 under the control of Scer\GAL4^ptc-559.1 along the anterior-posterior compartment boundary of the wing disc is suppressed if the cells are also co-expressing puc^Scer\UAS.cMa, but the abnormal apical folding phenotype is not suppressed.

(Jiang et al., 2011)

Co-expression of puc^Scer\UAS.cMa suppresses the increased apoptosis and increased fraction of mitotic cells phenotypes seen in Scer\GAL4^nub-AC-62, hppy^Scer\UAS.cMa discs.

(Resnik-Docampo and de Celis, 2011)

Clones of cells co-expressing nab^EP642 and puc^Scer\UAS.cMa in the wing imaginal disc (under the control of Scer\GAL4^{Scer\FRT.Rnor\CD2.Act5C}) exhibit a block on overgrowth.

(Suissa et al., 2011)

Co-expression of puc^Scer\UAS.cMa with scaf^Scer\UAS.cRa driven by Scer\GAL4^en-e16E enhances the male terminalia rotation phenotype observed when puc^Scer\UAS.cMa is expressed alone.

(Rousset et al., 2010)

Expression of puc^Scer\UAS.cMa under the control of Scer\GAL4^tub.PU strongly suppresses the apoptosis that is seen in mahj¹ or l(2)gl⁴ clones in the wing disc. Basal extrusion of mutant cells is not fully blocked in these discs.

(Tamori et al., 2010)

Scer\GAL4^GMR.PU-mediated co-expression of egr^{ecto-60.Scer\UAS.T:Ivir\HA1,T:Zzzz\FLAG} and puc^Scer\UAS.cMa results in a novel 'hanging-eye' phenotype. When co-expressed in wing disc clones, this combination induces apoptosis in neighbouring cells.

(Narasimamurthy et al., 2009)

The disruption of the actin cytoskeleton that is seen in the wing imaginal discs of animals expressing Vps4^{DN.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^Bx-MS1096-KE is partially suppressed by co-expression of puc^Scer\UAS.cMa.

Wing imaginal discs co-expressing both puc^Scer\UAS.cMa and Vps4^{DN.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^Bx-MS1096-KE are larger in size compared to controls.

(Rodahl et al., 2009)

The reduced eye size caused by expression of Rab11^{N124I.Scer\UAS} under the control of Scer\GAL4^GMR.PF is significantly suppressed by co-expression of puc^Scer\UAS.cMa.

(Tiwari and Roy, 2009)

Co-expression of puc^Scer\UAS.cMa ameliorates the eye defects caused by expression of Sir2^Scer\UAS.cGa under the control of Scer\GAL4^GMR.PU.

(Griswold et al., 2008)

Expression of puc^Scer\UAS.cMa (which inhibits cell death) in vg^null clones results in clone survival in the prospective wing blade of the larval wing disc. Clone survival depends on the position along the proximal-distal axis of growth, clones being recovered at a higher frequency and larger size in the proximal territories of the vg expression domain. These clones tend to be extruded during larval stages and fail to appear in the adult wing.

(Baena-Lopez and Garcia-Bellido, 2006)

Vps25^N55 Ark^H16/puc^Scer\UAS.cMa mosaic eye discs are severely overgrown.

(Herz et al., 2006)

The Fps85D^gof embryonic phenotype is rescued by expression of puc^Scer\UAS.cMa under the control of Scer\GAL4^wex1.for and Scer\GAL4^wex1.rev (the Scer\GAL4 alleles carried on the P{GawB-wex1}Fps85D^gof construct whose insertion causes the Fps85D^gof allele). puc^Scer\UAS.cMa, Fps85D^gof embryos complete dorsal closure at normal rates and show no axon misrouting at the ventral midline.

(Murray et al., 2006)

Expression of puc^Scer\UAS.cMa under the control of Scer\GAL4^ey.PH results in rescue of the ventral eye loss of L²/+ mutants in 36% of cases.

(Singh et al., 2006)

Expression of puc^Scer\UAS.cMa in Scer\GAL4^Act5C.PI>Ras85D^V12.Scer\UAS, scrib¹ eye/antennal imaginal disc clones prevents the invasion cell phenotype but does not rescue the overgrowth of the eye/antennal imaginal disc clones. puc^Scer\UAS.cMa expression rescues the larval lethality of Scer\GAL4^Act5C.PI>Ras85D^V12.Scer\UAS, scrib¹ clone-bearing animals and partially restores pupariation.

(Uhlirova and Bohmann, 2006)

puc^Scer\UAS.cMa suppresses the loss of apical profile, delamination and subsequent migration and cell death increase seen in cells at the posterior edge of the ptc expression domain in Csk^IR.Scer\UAS Scer\GAL4^ptc-559.1 third instar larvae.

(Vidal et al., 2006)

Overexpression of puc^Scer\UAS.cMa and park^{Scer\UAS.T:Hsap\MYC} in the notum of wing imaginal discs, under the regulation of Scer\GAL4^ap-md544 enhances the thoracic cleft observed in each single overexpression.

(Cha et al., 2005)

When 4xdmyc and 2xdmyc clones are made in wing discs that express puc^Scer\UAS.cMa (driven by Scer\GAL4^hh-Gal4) in the posterior compartment, 2xdmyc clones grow significantly more slowly than 4xdmyc clones in the Anterior (control) compartment. This effect is lessened in the posterior compartment. The 4xdmyc clones also grow less well in the posterior compartment.

(Moreno and Basler, 2004)

puc^Scer\UAS.cMa; Scer\GAL4^αTub84B.PL only partially rescues arr² homozygous somatic clone size in the wing disc: These clones are on average 32% of twin-spot clone size, compared to 17% in the absence of puc^Scer\UAS.cMa.

(Giraldez and Cohen, 2003)

The presence of puc^Scer\UAS.cMa suppresses the wing ablation phenotype seen in P{UAS-eiger.M}Av; Scer\GAL4^C-765 flies and the eye ablation phenotype due to egr^Scer\UAS.cMa with Scer\GAL4^GMR.PF. The presence of puc^Scer\UAS.cMa allows somatic clones expressing egr^Scer\UAS.cMa under the control of Scer\GAL4^Ubx.PdC in the wing disc to survive for at least 60 hours after induction. In the absence of puc^Scer\UAS.cMa all such clones are lost by 24 hours after induction.

(Moreno et al., 2002)

Co-expression of puc^Scer\UAS.cMa allows the survival of clones expressing brk^Scer\UAS.cJa under the control of Scer\GAL4^Ubx.PdC in the centre of the wing disc.

(Moreno et al., 2002)

Expression of puc^Scer\UAS.cMa under the control of Scer\GAL4^elav-C155 suppresses the effect of co-expression of kay^Scer\UAS.cEa and Jra^Scer\UAS.cEa (under the control of Scer\GAL4^elav-C155) on bouton number and EJC amplitude (synaptic strength) at the larval neuromuscular junction.

(Sanyal et al., 2002)

Suppresses the extra wing vein phenotype of flies expressing rl^Sem.Scer\UAS under the control of Scer\GAL4^455.2.

(Martin-Blanco, 1998)

Xenogenetic Interactions

Statement

Reference

The aggressive tissue overgrowth observed in third instar larval wing discs carrying somatic (flip-out) clones simultaneously expressing Snr1^HMS00363 and BacA\p35^Scer\UAS.cHa driven by Scer\GAL4^Act.PU is significantly suppressed by co-expression of puc^Scer\UAS.cMa.

(Xie et al., 2017)

Expression of puc^Scer\UAS.cMa enhances the reduction in eye size seen in both males and females when Zzzz\E4orf4^Scer\UAS.cPa is expressed under the control of Scer\GAL4^GMR.PF at any of 18[o]C, 24[o]C or 29[o]C.

(Pechkovsky et al., 2013)

Co-expression of puc^Scer\UAS.cMa significantly rescues the increase in cell death seen in the third larval instar eye disc of animals expressing Hsap\APP^{Aβ42.Scer\UAS.cUa} under the control of Scer\GAL4^GMR.PU and also strongly rescues the neurodegenerative phenotype of the adult eye.

(Tare et al., 2011)

Inhibition of cell death, through co-expression of BacA\p35^Scer\UAS.cHa and puc^Scer\UAS.cMa under the control of Scer\GAL4^unspecified, only slightly rescues the wing growth defects seen in vg^Scer\UAS.cKa, Scer\GAL4^unspecified flies.

(Baena-Lopez and Garcia-Bellido, 2006)

Coexpression of puc^Scer\UAS.cMa and BacA\p35^Scer\UAS.cHa, under the control of Scer\GAL4^ey.PH, does not affect the eye.

Coexpression of BacA\p35^Scer\UAS.cHa and puc^Scer\UAS.cMa under the control of Scer\GAL4^ey.PH rescues the ventral eye loss of L²/+ flies to a near wild-type eye in 69% of flies and pharate adults; this is a much greater suppression than that seen when either transgene is expressed without the other.

(Singh et al., 2006)

The eye neurodegeneration phenotype of Hsap\MJD^{Q78.Scer\UAS.T:Ivir\HA1}; Scer\GAL4^GMR.PF flies is not supressed by puc^Scer\UAS.cMa.

(Moreno et al., 2002)

Complementation and Rescue Data

Partially rescues

puc^UAS.cMa/Scer\GAL4^48Y partially rescues puc^GS16811

(Taniguchi et al., 2007)

puc^UAS.cMa/Scer\GAL4^NP3392 partially rescues puc^GS16811

(Taniguchi et al., 2007)

puc^UAS.cMa/Scer\GAL4^hs.PU partially rescues puc^GS16811

(Taniguchi et al., 2007)

Fails to rescue

puc^UAS.cMa/Scer\GAL4^dpp.PS fails to rescue puc^GS16811

(Taniguchi et al., 2007)

puc^UAS.cMa/Scer\GAL4^NP7020 fails to rescue puc^GS16811

(Taniguchi et al., 2007)

Comments

Expression of puc^Scer\UAS.cMa under the control of either Scer\GAL4^48Y or Scer\GAL4^Gap1-NP3392 completely rescues the left-right asymmetry defects seen in the anterior midgut of puc^GS16811 embryos. The defects in dorsal closure are not rescued.

The lack of left-right asymmetry in the tilting of the nuclei of the circular visceral muscle which is seen in late stage 15 and 16 puc^GS16811 embryos is rescued by expression of puc^Scer\UAS.cMa under the control of Scer\GAL4^Gap1-NP3392.

Expression of puc^Scer\UAS.cMa under the control of either Scer\GAL4^dpp.PS or Scer\GAL4^NP7020 does not rescue the left-right asymmetry defects seen in the anterior midgut of puc^GS16811 embryos.

Expression of puc^Scer\UAS.cMa under the control of Scer\GAL4^hs.PU using heat shock for 30 minutes at 37[o]C significantly rescues the left-right asymmetry defects seen in the anterior midgut of puc^GS16811 embryos when the heat shock is applied at any time during 4.5 to 9.5 AEL.

(Taniguchi et al., 2007)

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

98328

y¹ w^*; P{UAS-puc.M}3

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

puc^Scer\UAS.cMa

puc^UAS.cMa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Martin-Blanco

(Martin-Blanco et al., 1998)

Secondary FlyBase IDs

References (112)

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