Allele Dmel\ph-p^P1

General Information
Symbol	Dmel\ph-p^P1	Species	D. melanogaster
Name		FlyBase ID	FBal0086381
Feature type	allele	Associated gene	Dmel\ph-p
Also Known As	ph^P1

Map ( GBrowse )	Untitled Document
Allele class
Mutagen	P-element activity
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	P-element activity (Georgiev et al., 1998)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site X:2,030,470..2,030,470 (Belenkaya et al., 1998, Georgiev et al., 1998)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Insertion of a 1.2kb P-element into the untranslated leader sequence at 109bp (coordinate according to the cDNA clone map described in FBrf0054014). The P-element is transcribed in the same orientation as ph-p. Sequences between 829bp and 2560bp of the P-element are deleted, with the filler sequence TAGCTACAAA inserted at the breakpoint. (Belenkaya et al., 1998) Insertion of 1.2 kb P-element into the 5' transcribed non-translated region. (Georgiev et al., 1998)
Caused by insertion	P{}ph-p^P1 (Belenkaya et al., 1998, Georgiev et al., 1998)
Cytology
Phenotypic Data
Phenotypic Class
	wild-type (Georgiev et al., 1998)
Phenotype Manifest In

Detailed Description
	Statement Reference Mutation represses transcription of P-element-induced alleles at the y locus. The duplication and triplication of the P-element at the y locus enhanced the repression effect of the ph-p^P1 mutation. (Georgiev et al., 1998)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement Reference e(y)1^P1, ph-p^P1 has lethal \| embryonic stage phenotype, suppressible by e(y)1^+tSa (Soldatov et al., 1999) ph-p^P1, y^2s7 has body color defective phenotype, suppressible \| partially by su(Hw)² (Biryukova et al., 1999) ph-p^P1, y^2s7 has body color defective phenotype, suppressible \| partially by su(Hw)^V (Biryukova et al., 1999) ph-p^P1, y^2s11 has body color defective phenotype, suppressible \| partially by su(Hw)² (Biryukova et al., 1999) ph-p^P1, y^2s11 has body color defective phenotype, suppressible \| partially by su(Hw)^V (Biryukova et al., 1999) ph-p^P1, y^2s14 has body color defective phenotype, suppressible \| partially by sn^wP13 (Biryukova et al., 1999) ph-p^P1, y^2s14 has body color defective phenotype, suppressible \| partially by sn^wP14 (Biryukova et al., 1999) ph-p^P1, y^2s14 has body color defective phenotype, suppressible by sn^eP1 (Biryukova et al., 1999) ph-p^P1, y^2s14 has body color defective phenotype, suppressible by su(Hw)² (Biryukova et al., 1999) ph-p^P1, y^2s14 has body color defective phenotype, suppressible by su(Hw)^V (Biryukova et al., 1999) ph-p^P1, y^2s14 has body color defective phenotype, suppressible by Su(y)P22^P22/Su(y)P22[+] (Biryukova et al., 1999) ph-p^P1, y^2s14 has body color defective phenotype, suppressible by Su(y)P31[+]/Su(y)P31^P31 (Biryukova et al., 1999) ph-p^P1, y^2s16 has body color defective phenotype, suppressible by su(Hw)² (Biryukova et al., 1999) ph-p^P1, y^2s16 has body color defective phenotype, suppressible by su(Hw)^V (Biryukova et al., 1999) ph-p^P1, y^2s25 has body color defective phenotype, suppressible \| partially by su(Hw)² (Biryukova et al., 1999) ph-p^P1, y^2s25 has body color defective phenotype, suppressible \| partially by su(Hw)^V (Biryukova et al., 1999) ph-p^P1, y^2s26 has body color defective phenotype, suppressible \| partially by su(Hw)² (Biryukova et al., 1999) ph-p^P1, y^2s26 has body color defective phenotype, suppressible \| partially by su(Hw)^V (Biryukova et al., 1999) ph-p^P1, y^+s22 has body color defective phenotype, suppressible \| partially by sn^eP1/sn[+] (Biryukova et al., 1999) ph-p^P1, y^+s22 has body color defective phenotype, suppressible \| partially by su(Hw)² (Biryukova et al., 1999) ph-p^P1, y^+s22 has body color defective phenotype, suppressible \| partially by su(Hw)^V (Biryukova et al., 1999) ph-p^P1, y^+s22 has body color defective phenotype, suppressible \| partially by Su(y)P22^P22/Su(y)P22[+] (Biryukova et al., 1999) ph-p^P1, y^+s22 has body color defective phenotype, suppressible \| partially by Su(y)P31[+]/Su(y)P31^P31 (Biryukova et al., 1999) ph-p^P1, y^+s32 has body color defective phenotype, suppressible by su(Hw)² (Biryukova et al., 1999) ph-p^P1, y^+s32 has body color defective phenotype, suppressible by su(Hw)^V (Biryukova et al., 1999) ph-p^P1, y^+s has body color defective \| recessive phenotype, suppressible by sn^eP1/sn[+] (Biryukova et al., 1999) ph-p^P1, y^+s has body color defective \| recessive phenotype, suppressible by Su(y)P22^P22/Su(y)P22[+] (Biryukova et al., 1999) ph-p^P1, y^+s has body color defective \| recessive phenotype, suppressible by Su(y)P31[+]/Su(y)P31^P31 (Biryukova et al., 1999) ph-p^P1, y^+s has body color defective phenotype, suppressible by su(Hw)² (Biryukova et al., 1999) ph-p^P1, y^+s has body color defective phenotype, suppressible by su(Hw)^V (Biryukova et al., 1999) ph-p^P1, y^+sA8 has body color defective phenotype, suppressible \| partially by sn^eP1 (Biryukova et al., 1999) ph-p^P1, y^+sA8 has body color defective phenotype, suppressible \| partially by Su(y)P22^P22/Su(y)P22[+] (Biryukova et al., 1999) ph-p^P1, y^+sA8 has body color defective phenotype, suppressible \| partially by Su(y)P31[+]/Su(y)P31^P31 (Biryukova et al., 1999) ph-p^P1, y^+sA11 has body color defective phenotype, suppressible \| partially by su(Hw)² (Biryukova et al., 1999) ph-p^P1, y^+sA11 has body color defective phenotype, suppressible \| partially by su(Hw)^V (Biryukova et al., 1999) ph-p^P1, y^+sA12 has body color defective phenotype, suppressible \| partially by su(Hw)² (Biryukova et al., 1999) ph-p^P1, y^+sA12 has body color defective phenotype, suppressible \| partially by su(Hw)^V (Biryukova et al., 1999) ph-p^P1, y^+sA22 has body color defective phenotype, suppressible \| partially by sn^eP1 (Biryukova et al., 1999) ph-p^P1, y^+sA22 has body color defective phenotype, suppressible \| partially by Su(y)P22^P22/Su(y)P22[+] (Biryukova et al., 1999) ph-p^P1, y^+sA22 has body color defective phenotype, suppressible \| partially by Su(y)P31[+]/Su(y)P31^P31 (Biryukova et al., 1999)
NOT suppressed by
Statement Reference ph-p^P1, y^2s7 has body color defective phenotype, non-suppressible by sn^eP1 (Biryukova et al., 1999) ph-p^P1, y^2s7 has body color defective phenotype, non-suppressible by Su(y)P22^P22 (Biryukova et al., 1999) ph-p^P1, y^2s7 has body color defective phenotype, non-suppressible by Su(y)P31^P31 (Biryukova et al., 1999) ph-p^P1, y^2s11 has body color defective phenotype, non-suppressible by sn^eP1 (Biryukova et al., 1999) ph-p^P1, y^2s11 has body color defective phenotype, non-suppressible by Su(y)P22^P22 (Biryukova et al., 1999) ph-p^P1, y^2s11 has body color defective phenotype, non-suppressible by Su(y)P31^P31 (Biryukova et al., 1999) ph-p^P1, y^2s14 has body color defective phenotype, non-suppressible by sn^+P11 (Biryukova et al., 1999) ph-p^P1, y^2s14 has body color defective phenotype, non-suppressible by sn^+P12 (Biryukova et al., 1999) ph-p^P1, y^2s25 has body color defective phenotype, non-suppressible by sn^eP1 (Biryukova et al., 1999) ph-p^P1, y^2s25 has body color defective phenotype, non-suppressible by Su(y)P22^P22 (Biryukova et al., 1999) ph-p^P1, y^2s25 has body color defective phenotype, non-suppressible by Su(y)P31^P31 (Biryukova et al., 1999) ph-p^P1, y^2s26 has body color defective phenotype, non-suppressible by sn^eP1 (Biryukova et al., 1999) ph-p^P1, y^2s26 has body color defective phenotype, non-suppressible by Su(y)P22^P22 (Biryukova et al., 1999) ph-p^P1, y^2s26 has body color defective phenotype, non-suppressible by Su(y)P31^P31 (Biryukova et al., 1999)
Enhancer of
Statement Reference ph-p^P1 is an enhancer of body color defective \| recessive phenotype of y^+s (Biryukova et al., 1999) ph-p^P1 is an enhancer of body color defective phenotype of y^2s2 (Biryukova et al., 1999) ph-p^P1 is an enhancer of body color defective phenotype of y^2s7 (Biryukova et al., 1999, Belenkaya et al., 1998) ph-p^P1 is an enhancer of body color defective phenotype of y^2s10-2 (Biryukova et al., 1999) ph-p^P1 is an enhancer of body color defective phenotype of y^2s11 (Biryukova et al., 1999, Belenkaya et al., 1998) ph-p^P1 is an enhancer of body color defective phenotype of y^2s14 (Belenkaya et al., 1998, Biryukova et al., 1999) ph-p^P1 is an enhancer of body color defective phenotype of y^2s16 (Biryukova et al., 1999) ph-p^P1 is an enhancer of body color defective phenotype of y^2s20 (Belenkaya et al., 1998) ph-p^P1 is an enhancer of body color defective phenotype of y^2s25 (Biryukova et al., 1999) ph-p^P1 is an enhancer of body color defective phenotype of y^2s26 (Biryukova et al., 1999) ph-p^P1 is an enhancer of body color defective phenotype of y^2s42 (Biryukova et al., 1999) ph-p^P1 is an enhancer of body color defective phenotype of y^2sA3 (Belenkaya et al., 1998) ph-p^P1 is an enhancer of body color defective phenotype of y^76d28 (Belenkaya et al., 1998) ph-p^P1 is an enhancer of body color defective phenotype of y^+s22 (Biryukova et al., 1999) ph-p^P1 is an enhancer of body color defective phenotype of y^+s32 (Biryukova et al., 1999) ph-p^P1 is an enhancer of body color defective phenotype of y^+sA11 (Biryukova et al., 1999) ph-p^P1 is an enhancer of body color defective phenotype of y^+sA12 (Biryukova et al., 1999) ph-p^P1 is an enhancer of body color defective phenotype of y^ds62 (Belenkaya et al., 1998) ph-p^P1 is an enhancer of body color defective phenotype of y^ΔP.tBa (Biryukova et al., 1999) ph-p^P1 is an enhancer of eye color defective phenotype of w^ΔP (Biryukova et al., 1999) ph-p^P1 is an enhancer of visible \| homeotic phenotype of Trf2^P1 (Kopytova et al., 2006)
Other
Statement Reference e(y)1^P1, ph-p^P1 has lethal \| embryonic stage phenotype (Soldatov et al., 1999, Soldatov et al., 1999) ph-p^P1, y^+s7 has body color defective phenotype (Belenkaya et al., 1998) ph-p^P1, y^+s8 has body color defective phenotype (Belenkaya et al., 1998) ph-p^P1, y^+sA8 has body color defective phenotype (Biryukova et al., 1999) ph-p^P1, y^+sA22 has body color defective phenotype (Biryukova et al., 1999) Trf2^P1, ph-p^P1 has female sterile phenotype (Kopytova et al., 2006) Trf2^P1, ph-p^P1 has lethal \| embryonic stage phenotype (Kopytova et al., 2006) Trf2^P1, ph-p^P1 has lethal \| larval stage phenotype (Kopytova et al., 2006) Trf2^P1, ph-p^P1 has lethal \| pupal stage phenotype (Kopytova et al., 2006) Trf2^P1, ph-p^P1 has male sterile \| partially phenotype (Kopytova et al., 2006) Trf2^P1, ph-p^P1 has short lived phenotype (Kopytova et al., 2006) Trf2^P1, ph-p^P1 has visible phenotype (Kopytova et al., 2006)
Phenotype Manifest In
Enhancer of
Statement Reference ph-p^P1 is an enhancer of adult abdomen & macrochaeta phenotype of y^2s2 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult abdomen & macrochaeta phenotype of y^2s7 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult abdomen & macrochaeta phenotype of y^2s10-2 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult abdomen & macrochaeta phenotype of y^2s11 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult abdomen & macrochaeta phenotype of y^2s14 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult abdomen & macrochaeta phenotype of y^2s16 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult abdomen & macrochaeta phenotype of y^2s25 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult abdomen & macrochaeta phenotype of y^2s26 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult abdomen & macrochaeta phenotype of y^+s22 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult abdomen & macrochaeta phenotype of y^+s (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult abdomen & macrochaeta phenotype of y^+sA11 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult abdomen & macrochaeta phenotype of y^+sA12 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult abdominal sensillum phenotype of y^76d28 (Belenkaya et al., 1998) ph-p^P1 is an enhancer of adult cuticle phenotype of y^2s7 (Belenkaya et al., 1998) ph-p^P1 is an enhancer of adult cuticle phenotype of y^2s11 (Belenkaya et al., 1998) ph-p^P1 is an enhancer of adult cuticle phenotype of y^76d28 (Belenkaya et al., 1998) ph-p^P1 is an enhancer of adult cuticle phenotype of y^ds62 (Belenkaya et al., 1998) ph-p^P1 is an enhancer of adult thorax & macrochaeta phenotype of y^2s2 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult thorax & macrochaeta phenotype of y^2s7 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult thorax & macrochaeta phenotype of y^2s10-2 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult thorax & macrochaeta phenotype of y^2s11 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult thorax & macrochaeta phenotype of y^2s14 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult thorax & macrochaeta phenotype of y^2s16 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult thorax & macrochaeta phenotype of y^2s25 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult thorax & macrochaeta phenotype of y^2s26 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult thorax & macrochaeta phenotype of y^2s42 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult thorax & macrochaeta phenotype of y^76d28 (Belenkaya et al., 1998) ph-p^P1 is an enhancer of adult thorax & macrochaeta phenotype of y^+s22 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult thorax & macrochaeta phenotype of y^+s32 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult thorax & macrochaeta phenotype of y^+s (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult thorax & macrochaeta phenotype of y^+sA11 (Biryukova et al., 1999) ph-p^P1 is an enhancer of adult thorax & macrochaeta phenotype of y^+sA12 (Biryukova et al., 1999) ph-p^P1 is an enhancer of arista phenotype of Trf2^P1 (Kopytova et al., 2006) ph-p^P1 is an enhancer of leg sensillum phenotype of y^2s2 (Biryukova et al., 1999) ph-p^P1 is an enhancer of leg sensillum phenotype of y^2s7 (Biryukova et al., 1999) ph-p^P1 is an enhancer of leg sensillum phenotype of y^2s10-2 (Biryukova et al., 1999) ph-p^P1 is an enhancer of leg sensillum phenotype of y^2s11 (Biryukova et al., 1999) ph-p^P1 is an enhancer of leg sensillum phenotype of y^2s14 (Biryukova et al., 1999) ph-p^P1 is an enhancer of leg sensillum phenotype of y^2s16 (Biryukova et al., 1999) ph-p^P1 is an enhancer of leg sensillum phenotype of y^2s25 (Biryukova et al., 1999) ph-p^P1 is an enhancer of leg sensillum phenotype of y^2s26 (Biryukova et al., 1999) ph-p^P1 is an enhancer of leg sensillum phenotype of y^2s42 (Biryukova et al., 1999) ph-p^P1 is an enhancer of leg sensillum phenotype of y^+s22 (Biryukova et al., 1999) ph-p^P1 is an enhancer of leg sensillum phenotype of y^+s32 (Biryukova et al., 1999) ph-p^P1 is an enhancer of leg sensillum phenotype of y^+s (Biryukova et al., 1999) ph-p^P1 is an enhancer of leg sensillum phenotype of y^+sA11 (Biryukova et al., 1999) ph-p^P1 is an enhancer of leg sensillum phenotype of y^+sA12 (Biryukova et al., 1999) ph-p^P1 is an enhancer of macrochaeta phenotype of y^ΔP.tBa (Biryukova et al., 1999) ph-p^P1 is an enhancer of mesothoracic leg sensillum phenotype of y^76d28 (Belenkaya et al., 1998) ph-p^P1 is an enhancer of metathoracic leg sensillum phenotype of y^76d28 (Belenkaya et al., 1998) ph-p^P1 is an enhancer of pigment cell phenotype of w^ΔP (Biryukova et al., 1999) ph-p^P1 is an enhancer of prothoracic leg sensillum phenotype of y^76d28 (Belenkaya et al., 1998) ph-p^P1 is an enhancer of tarsal segment \| ectopic phenotype of Trf2^P1 (Kopytova et al., 2006) ph-p^P1 is an enhancer of wing phenotype of y^2s7 (Biryukova et al., 1999, Belenkaya et al., 1998) ph-p^P1 is an enhancer of wing phenotype of y^2s10-2 (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing phenotype of y^2s11 (Biryukova et al., 1999, Belenkaya et al., 1998) ph-p^P1 is an enhancer of wing phenotype of y^2s25 (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing phenotype of y^2s26 (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing phenotype of y^+s22 (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing phenotype of y^+s32 (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing phenotype of y^+s (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing phenotype of y^+sA11 (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing phenotype of y^+sA12 (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing phenotype of y^ds62 (Belenkaya et al., 1998) ph-p^P1 is an enhancer of wing sensillum phenotype of y^2s2 (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing sensillum phenotype of y^2s7 (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing sensillum phenotype of y^2s10-2 (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing sensillum phenotype of y^2s11 (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing sensillum phenotype of y^2s14 (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing sensillum phenotype of y^2s16 (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing sensillum phenotype of y^2s25 (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing sensillum phenotype of y^2s26 (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing sensillum phenotype of y^76d28 (Belenkaya et al., 1998) ph-p^P1 is an enhancer of wing sensillum phenotype of y^+s22 (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing sensillum phenotype of y^+sA11 (Biryukova et al., 1999) ph-p^P1 is an enhancer of wing sensillum phenotype of y^+sA12 (Biryukova et al., 1999)
NOT Enhancer of
Statement Reference ph-p^P1 is a non-enhancer of phenotype of sn^e (Biryukova et al., 1999) ph-p^P1 is a non-enhancer of phenotype of sn^eP1 (Biryukova et al., 1999) ph-p^P1 is a non-enhancer of phenotype of sn^w (Biryukova et al., 1999) ph-p^P1 is a non-enhancer of phenotype of sn^wP13 (Biryukova et al., 1999) ph-p^P1 is a non-enhancer of phenotype of sn^wP14 (Biryukova et al., 1999) ph-p^P1 is a non-enhancer of phenotype of y² (Belenkaya et al., 1998) ph-p^P1 is a non-enhancer of phenotype of y^2s34 (Biryukova et al., 1999) ph-p^P1 is a non-enhancer of phenotype of y^+ews1 (Belenkaya et al., 1998) ph-p^P1 is a non-enhancer of phenotype of y^+ews2 (Belenkaya et al., 1998) ph-p^P1 is a non-enhancer of phenotype of y^+ls4 (Belenkaya et al., 1998) ph-p^P1 is a non-enhancer of phenotype of y^+s27 (Biryukova et al., 1999) ph-p^P1 is a non-enhancer of phenotype of y^tBa (Biryukova et al., 1999)
Other
Statement Reference ph-p^P1, y^2s7 has adult abdominal sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s7 has adult thorax & macrochaeta phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s7 has mesothoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s7 has metathoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s7 has prothoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s7 has wing sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s11 has adult abdominal sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s11 has adult thorax & macrochaeta phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s11 has mesothoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s11 has metathoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s11 has prothoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s11 has wing sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s14 has adult abdominal sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s14 has adult thorax & macrochaeta phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s14 has mesothoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s14 has metathoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s14 has prothoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s14 has wing sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s20 has adult abdominal sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s20 has adult thorax & macrochaeta phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s20 has mesothoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s20 has metathoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s20 has prothoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2s20 has wing sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2sA3 has adult abdominal sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2sA3 has adult thorax & macrochaeta phenotype (Belenkaya et al., 1998) ph-p^P1, y^2sA3 has mesothoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2sA3 has metathoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2sA3 has prothoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^2sA3 has wing sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^+s7 has adult cuticle phenotype (Belenkaya et al., 1998) ph-p^P1, y^+s7 has adult thorax & macrochaeta phenotype (Belenkaya et al., 1998) ph-p^P1, y^+s7 has mesothoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^+s7 has metathoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^+s7 has prothoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^+s8 has adult cuticle phenotype (Belenkaya et al., 1998) ph-p^P1, y^+s8 has adult thorax & macrochaeta phenotype (Belenkaya et al., 1998) ph-p^P1, y^+s8 has mesothoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^+s8 has metathoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^+s8 has prothoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^ds62 has adult abdominal sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^ds62 has adult thorax & macrochaeta phenotype (Belenkaya et al., 1998) ph-p^P1, y^ds62 has mesothoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^ds62 has metathoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^ds62 has prothoracic leg sensillum phenotype (Belenkaya et al., 1998) ph-p^P1, y^ds62 has wing sensillum phenotype (Belenkaya et al., 1998) Trf2^P1, ph-p^P1 has egg chamber phenotype (Kopytova et al., 2006) Trf2^P1, ph-p^P1 has embryonic segment phenotype (Kopytova et al., 2006) Trf2^P1, ph-p^P1 has karyosome phenotype (Kopytova et al., 2006) Trf2^P1, ph-p^P1 has presumptive embryonic/larval central nervous system phenotype (Kopytova et al., 2006) Trf2^P1, ph-p^P1 has presumptive embryonic/larval peripheral nervous system phenotype (Kopytova et al., 2006) Trf2^P1, ph-p^P1 has primary spermatocyte phenotype (Kopytova et al., 2006) Trf2^P1, ph-p^P1 has spermatocyte phenotype (Kopytova et al., 2006) Trf2^P1, ph-p^P1 has testis phenotype (Kopytova et al., 2006)
Additional Comments
Genetic Interactions
Statement Reference The viability of ph-p[P1] Trf2[P1] double mutants is strongly decreased. Mortality is seen at the late embryonic stage (approximately 50%) and larval and pupal stages (approximately 30%). Approximately 10% of double hemizygous males and 1% of double homozygous females survive to adulthood. The adults die in 5 to 10 days after eclosion. The double homozygous females are completely sterile and the double hemizygous males have decreased fertility. Approximately 30% of the adults have an extreme transformation of arista to tarsus. The adults have shortened bodies. Approximately 10% of ph-p[P1] Trf2[P1] double mutant embryos have defects in central nervous system development, and approximately 20% of the mutant embryos have defects in the ventral and lateral clusters of the embryonic peripheral nervous system. Defects in segment organisation are seen in approximately 15% of the embryos. The karyosome often appears more diffuse than normal in ph-p[P1] Trf2[P1] double mutant oocytes. ph-p[P1] Trf2[P1] double mutant ovaries contain few mature oocytes and have abnormally shaped egg chambers. The ovarioles often contain several follicles that have not separated from the germarium. Many egg chambers contain more than the normal number of 16 nuclei, representing joint cysts packaged inside a monolayer of follicle cells. ph-p[P1] Trf2[P1] double mutant males have thinner testes than wild-type males. No abnormalities are seen in young primary spermatocytes, but at later stages, many primary spermatocytes show differentiation defects; the chromosome bivalents look more diffuse during metaphase, and aberrant spindles are seen. A significant number of cysts in the mutant testis contain abnormal mature spermatocytes that are probably necrotic. (Kopytova et al., 2006) Lethal during the middle and late embryonic stages in combination with e(y)1^P1. This phenotype is rescued by e(y)1^+tSa. (Soldatov et al., 1999)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	Mutation encodes a chimeric P-element-ph-p protein, consisting of the DNA binding domain of the P-element and theph-pPh protein lacking 12 amino-terminal amino acids. (Georgiev et al., 1998)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	ph^P1 (Biryukova et al., 1999, Soldatov et al., 1999, Belenkaya et al., 1998, Belenkaya et al., 1998, Georgiev et al., 1998, Kopytova et al., 2006) phP1 (Belenkaya et al., 1998) ph-p^P1
Name Synonym
Secondary FlyBase IDs

References ( 7 )
Research paper	Kopytova et al., 2006, Mol. Cell. Biol. 26(20): 7492--7505 Two isoforms of Drosophila TRF2 are involved in embryonic development, premeiotic chromatin condensation, and proper differentiation of germ cells of both sexes. [FBrf0192356] Biryukova et al., 1999, Genetics 152(4): 1641--1652 The P-Ph protein-mediated repression of yellow expression depends on different cis- and trans-factors in Drosophila melanogaster. [FBrf0109352] Soldatov et al., 1999, Mol. Cell. Biol. 19(5): 3769--3778 TAFII40 protein is encoded by the e(y)1 gene: biological consequences of mutations. [FBrf0108279] Belenkaya et al., 1998, Genetics 150(2): 687--697 P-Element insertion at the polyhomeotic gene leads to formation of a novel chimeric protein that negatively regulates yellow gene expression in P-element-induced alleles of Drosophila melanogaster. [FBrf0104732] Belenkaya et al., 1998, Mol. Gen. Genet. 259(1): 79--87 P element sequences can compensate for a deletion of the yellow regulatory region in Drosophila melanogaster. [FBrf0104405]
Abstract	Belenkaya et al., 1998, HHMI, Int. Res. Scholars, 1998: 46 P element insertion at the polyhomoetic gene leads to formation of a novel chimeric protein that negatively regulates the yellow expression in the P element-induced y alleles of Drosophila melanogaster. [FBrf0103640] Georgiev et al., 1998, A. Dros. Res. Conf. 39: 778C P element insertion at the polyhomeotic gene leads to formation of a novel chimeric protein, that negatively regulates theyellow expression in the P element inducedy alleles of Drosophila melanogaster. [FBrf0101814]

Allele Dmel\ph-pP1

Allele Dmel\ph-p^P1