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General Information
Symbol
Dmel\mod(mdg4)T16
Species
D. melanogaster
Name
FlyBase ID
FBal0086404
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    mod(mdg4)Z3-3401/mod(mdg4)T16 males show a low frequency of 4th chromosome loss in meiosis (7.9%).

    Homologous pairing in pre-meiotic spermatogonia and in early prophase I spermatocytes appears normal in mod(mdg4)Z3-3401/mod(mdg4)T16 males.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Enhanced by
    Statement
    Reference

    ash117, mod(mdg4)T16/mod(mdg4)[+] has visible | dominant | homeotic phenotype, enhanceable by trxB11/trx[+]

    Enhancer of
    Statement
    Reference

    mod(mdg4)T16/mod(mdg4)[+] is an enhancer of visible | dominant | homeotic phenotype of brm2, trx[+]/trxE2

    mod(mdg4)T16/mod(mdg4)[+] is an enhancer of visible | dominant | homeotic phenotype of brm[+]/brm2, trxE2

    mod(mdg4)T16/mod(mdg4)[+] is an enhancer of visible | dominant | homeotic phenotype of ash1[+]/ash117, trxB11

    NOT Enhancer of
    Statement
    Reference
    NOT Suppressor of
    Statement
    Reference
    Other
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Body colour: y2 ; mod(mdg4)T6/mod(mdg4)T16 and y2 ; mod(mdg4)Z3-3401/mod(mdg4)T16 flies have a y- phenotype (yellow bristles, wings and bodies).

    Body colour: the y2 phenotype (black bristles, yellow body and wings) is not altered by mod(mdg4)Z3-5578/mod(mdg4)T16.

    mod(mdg4)T16 trxB11 double heterozygotes show a transformation of haltere to wing in 1.4% of cases. mod(mdg4)T16/+ or trxB11/+ single heterozygotes do not show this homeotic transformation. Increases the frequency of homeotic transformations seen in Trl62 heterozygotes. Increases the frequency of homeotic transformations seen in trxB11 ash117 double heterozygotes. Increases the frequency of homeotic transformations seen in trxE2 brm2 double heterozygotes. Dominantly suppresses the frequency and severity of homeotic transformations seen in Df(3L)Pc heterozygotes.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Partially rescued by
    Comments

    The lethal phenotype of mod(mdg4)T16 is fully complemented by mod(mdg4)Z3-3401, mod(mdg4)Z3-5578 and mod(mdg4)Z3-3298, but mod(mdg4)T16 fails to complement these alleles with respect to X-Y chromosome nondisjunction in male meiosis - the transheterozygotes show a high level of X-Y nondisjunction (frequency is indicated in parentheses after each allele); mod(mdg4)Z3-3401 (39.6%), mod(mdg4)Z3-5578 (44.3%) and mod(mdg4)Z3-3298 (44.6%).

    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (3)