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General Information
Symbol
Dmel\linunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0086412
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Homozygous clones generated at the early first larval instar in the peripodial epithelium of the wing disc survive.

    Homozygous clones generated at the early first larval instar in the disc proper of the wing disc show reduced survival compared to wild-type twin spots. Those that do survive are much smaller than their respective wild-type twin spots.

    Homozygous clones generated at the second larval instar in the disc proper of the wing disc survive poorly compared to their wild-type twin spots. The surviving clones extrude basally from the disc proper. Occasionally, clones that originate in the disc proper grow to a large size.

    Homozygous clones generated at the mid- to late third larval instar in the disc proper and the posterior lateral margin of the hinge of the wing disc minimise contact with their wild-type neighbours are form round vesicles that extrude basally.

    The 4o fate of the dorsal epidermis is replaced with 1o-3o fates in mutant embryos.

    In linunspecified homozygous embryos, both the foregut and the hindgut are bloated, boundary cells are missing from the hindgut, and the keyhole region of the foregut is expanded.

    The hindgut is wider and shorter than normal in mutant embryos. The hindgut appears distended, the large intestine is missing and the boundary cell rows that normally run along the length of the large intestine are missing. The foregut is shorter and wider than normal and the proventriculus does not form.

    The cuticle phenotype of embryos lacking both maternal and zygotic lin activity is indistinguishable from that of zygotic lin mutants.

    A small anterior portion of each segment is deleted in linunspecified mutant embryos. Segment A8, spiracles and anal plates are absent. The head is abnormal.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    NOT Enhanced by
    NOT suppressed by
    NOT Enhancer of
    Statement
    Reference

    linunspecified is a non-enhancer of embryonic foregut phenotype of bowl1

    linunspecified is a non-enhancer of keyhole structure phenotype of bowl1

    NOT Suppressor of
    Statement
    Reference

    linunspecified is a non-suppressor of keyhole structure phenotype of bowl1

    linunspecified is a non-suppressor of embryonic foregut phenotype of bowl1

    Other
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    The dorsal cuticle phenotype of linunspecified bowlunspecified double mutant embryos is the same as that of bowlunspecified single mutant embryos. The dorsal cuticle phenotype of drmunspecified linunspecified double mutant embryos is the same as that of linunspecified single mutant embryos.

    linunspecified; drmunspecified double homozygous embryos have a foregut phenotype identical to those of linunspecified homozygotes (bloated and with an expanded keyhole structure), rather than drmunspecified homozygotes (narrow and lacking a keyhole structure). linunspecified; bowl1 double homozygous embryos have a foregut phenotype identical to those of bowl1 homozygotes (narrow and lacking a keyhole structure), rather than linunspecified homozygotes (bloated and with an expanded keyhole structure).

    linunspecified drmunspecified double mutant embryos have the same mutant hindgut and foregut phenotypes as linunspecified single mutant embryos.

    The dorsal patterning defects in linunspecified embryos are not rescued by the expression of wgScer\UAS.cLa under the control of Scer\GAL4arm.PS.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    linunspecified
    Name Synonyms
    Secondary FlyBase IDs
      References (6)