FB2025_02 , released April 17, 2025
Allele: Dmel\aos::spiAS.UAS
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General Information
Symbol
Dmel\aos::spiAS.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0086579
Feature type
allele
Associated gene
aos::spi
Associated Insertion(s)
Carried in Construct
P{UAS-gil::spi.AS}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Howes et al., 1998)
Progenitor genotype
Carried in construct
P{UAS-gil::spi.AS}
Cytology
Description

UASt regulatory sequences drive expression of a chimeric protein in which the C-terminal region of aos (including the EGF domain) has been replaced with the C-terminal region of spi (amino acids 63 to 128, which includes the spi EGF domain).

(Howes et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
aos::spi
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of argos::spiAS.Scer\UAS in the developing wing blade using Scer\GAL4Bx-MS1096 causes the formation of extra wing veins.

      (Howes et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Scer\GAL4hs.2sev/aos::spiAS.UAS is a suppressor of eye phenotype of spiSCP1

      (Howes et al., 1998)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Partially rescues the rough eye phenotype of spiSCP1 homozygotes when expressed under the control of Scer\GAL4hs.2sev.

      (Howes et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      aos::spiAS.Scer\UAS
      aos::spiAS.UAS
      argos::spiAS.Scer\UAS
      argos::spiAS.UAS
      gil::spiAS.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)