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General Information
Symbol
Dmel\foiunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0086619
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Germ cell migration occurs normally in mutant embryos and the germ cells are able to correctly associate with the gonadal mesoderm. However, the germ cells fail to form the tight cluster typically found in a properly coalesced gonad and instead remain loosely aligned. Mutants die at the end of embryogenesis, with no general defects in the nervous system, midgut, musculature or cuticle pattern.
Fas2-positive nerve bundles frequently cross the midline in mutant embryos, in contrast to wild-type.
Mutants exhibit failure of the ability of germ cells and the gonadal mesoderm to coalesce into the embryonic gonad. Very late stage embryos exhibit germ cells and somatic gonadal precursors (SGPs) remaining in a line, instead of the characteristic round shape of the gonads by stage 14. The SGPs appear as if they are incapable of making close contacts with one another.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement
Reference
Enhancer of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
foiunspecified pntunspecified or foiunspecified klounspecified double mutant embryos show a slightly enhanced fused commissure phenotype compared to the phenotypes of the single mutants. The number of midline glial cells is reduced in the double mutant embryos.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments
3 mutants are isolated.
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
foiunspecified
kasunspecified
Name Synonyms
Secondary FlyBase IDs
  • FBal0095352
References (4)