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General Information
Symbol
Dmel\cutletrJ865a
Species
D. melanogaster
Name
FlyBase ID
FBal0086666
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{PZ} insertion after nucleotide 115 of the cutlet transcript. The insertion disrupts the 4th amino acid after the putative initiator methionine. The P{PZ} element is inserted in the opposite orientation to that of the cutlet transcript.

Insertion components
P{PZ}cutletrJ865a
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The penetrance of the female sterile and rough eye phenotypes in cutletrJ865a/Df(2L)ed1 flies is more than 99%. The penetrance of the wing phenotype is 38%. Homozygous eyes contain numerous ommatidial clusters with less than the normal number of photoreceptor cells. The positions of the missing cells suggest that they correspond to presumptive photoreceptors R1, R6 and R7. Homozygous clones grow more slowly than their wild-type twin spots in the eye, wing and leg discs.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

cutletrJ865a has visible | recessive phenotype, enhanceable by RfC38k13807/RfC38[+]

Phenotype Manifest In
Enhanced by
Statement
Reference

cutletrJ865a has ommatidium phenotype, enhanceable by RfC38k13807/RfC38[+]

cutletrJ865a has ommatidium phenotype, enhanceable by RfC40[+]/RfC4B6

cutletrJ865a has eye photoreceptor cell phenotype, enhanceable by RfC40[+]/RfC4B6

Additional Comments
Genetic Interactions
Statement
Reference

The cutletrJ865a eye phenotype is enhanced by one copy of RfC40B6 or RfC38k13807; the majority of ommatidial clusters in these flies have an abnormal number of photoreceptor cells and a large number of ommatidia are fused.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Induced with: P{PZ}rJ865b. The recessive lethal "l(2)rJ865" line originally contained two P{PZ} insertions; P{PZ}cutletrJ865a at 24B1--24B2 and the putatively lethal P{PZ}rJ865b insertion at 33E7--33E8.

Comments
Comments

Excision of the P{PZ} element can revert the phenotype to wild type.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
cutletrJ865a
Name Synonyms
Secondary FlyBase IDs
    References (2)