Allele Dmel\cswlf
| General Information | |||
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| Symbol | Dmel\cswlf | Species | D. melanogaster |
| Name | FlyBase ID | FBal0086671 | |
| Feature type | allele | Associated gene | Dmel\csw |
| Allele class | |||
| Mutagen | spontaneous | ||
Recent Updates
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| Description |
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| FB2012_01 | |||
| FB2011_10 | |||
| All updates | Click here to see a list of all updates to this record from FB2010_08 and on. | ||
Nature of the Allele
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| Allele class | |||
| Mutagen | |||
| Mutations Mapped to the Genome | |||
Type Location Additional Notes References | |||
| Associated Sequence Data | |||
| DDBJ
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EMBL / GenBank | DNA sequence Protein sequence Name | ||
| UniProtKB/Swiss-Prot | |||
| UniProtKB/TrEMBL | |||
| Progenitor genotype | |||
| Nature of the lesion | Statement Reference | ||
| Cytology | |||
Phenotypic Data
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Phenotypic Class
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Phenotype Manifest In
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Detailed Description
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Statement Reference csw[lf]/Y flies show loss of wing vein material. Homozygotes have a reproducible rough eye and wing vein gap phenotype. Stronger phenotypes are seen at higher temperatures. The rough eye phenotype results from a loss of photoreceptors, commonly R7, although there is also occasional loss of outer photoreceptors. The wing vein gaps are most frequently seen in the distal regions of L5 and L2, and occasional gaps are seen in L4. Homozygous females are essentially sterile and only rarely produce fertilised eggs. The eggs from homozygous females have shells that are partially ventralised; the dorsal appendages are partially fused. Embryos derived from homozygous females fail to hatch. Embryos derived from a cross of females containing homozygous germline clones to hemizygous males fail to hatch. The cuticles of these embryos are largely wild type, although mild defects such as partial fusion of denticle bands along the midline, mild twisting and incomplete germ band shortening are frequently seen. The eve-expressing DA1/#1 and pericardial cell precursors are variably missing. The VA2#27 muscle precursor is also variably missing. Embryos show either relatively little tracheal disruption (such as interruption of the dorsal trunk) or significant disruption where the dorsal trunk is interrupted one or more times along the anteroposterior axis and the dorsoventral tracheal branch pattern is misrouted. Rough eye and vein gap phenotypes. | |||
External Data
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Interactions
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Phenotypic Class
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Enhanced by | |||
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NOT Enhanced by | |||
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Suppressed by | |||
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NOT suppressed by | |||
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Enhancer of | |||
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Suppressor of | |||
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Other | |||
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Phenotype Manifest In
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Enhanced by | |||
Statement Reference cswlf has phenotype, enhanceable by Ras85DΔC40B | |||
NOT Enhanced by | |||
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Suppressed by | |||
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NOT suppressed by | |||
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Other | |||
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Additional Comments
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Genetic Interactions
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Statement Reference The supernumerary R7 cell and rough eye phenotype produced by Ras85DV12.sev is suppressed by cswlf. The rough eye phenotype and loss of R7 cells produced by Ras85DN17.sev is enhanced by cswlf/Y. The supernumerary R7 cell and rough eye phenotype produced by phl::torhs.sev is suppressed by cswlf/Y. cswlf/Y ; aopS2382/+ flies are poorly viable. Those flies that do eclose have extremely small, rough eyes. The cswlf/Y rough eye phenotype is dominantly enhanced by pntΔ88 or pnt07825. The cswlf/Y wing vein gap phenotype is enhanced by pnt07825 but not by pntΔ88. cswlf/Y suppresses the blistered wing and ectopic vein phenotype of In(2LR)Px4 or Df(2R)Px2 heterozygotes. bs3 shows weak or no suppression of the cswlf eye phenotype. | |||
Xenogenetic Interactions
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Statement Reference | |||
Complementation & Rescue Data
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| Rescued by | |||
| Comments | |||
Stocks
( 1 ) | |||
| Bloomington | |||
Notes on Origin
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| Discoverer | |||
External Crossreferences & Linkouts
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Synonyms & Secondary IDs
( 1 ) | |||
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References
( 6 ) | |||
| Research paper |
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| Personal communication to FlyBase |
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| Abstract |
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Recent Updates
External Crossreferences & Linkouts