FB2025_01 , released February 20, 2025
Allele: Dmel\cactunspecified
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General Information
Symbol
Dmel\cactunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0086695
Feature type
allele
Associated gene
Dmel\cact
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        In embryos derived from homozygous cact loss-of-function mutant females an expansion of ventral cell fates at the expense of dorsal fates is seen. Amnioserosa and dorsal ectoderm are not specified. Leading edge cells are also missing.

        (Stronach and Perrimon, 2001)

        The number of cells in division in the lymph glands of homozygous third instar larvae is higher than in wild-type larvae. The number of dividing hemocytes in the hemolymph of homozygous larvae is significantly higher than in wild-type.

        (Qiu et al., 1998)

        Embryos derived from homozygous females are ventralised, with the dorsal cuticle reduced or absent, and denticle bands expanded dorsally. Haploinsufficiency causes weak ventralisation.

        (Tearle and Nusslein-Volhard, 1987)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        cactunspecified is rescued by cactΔPEST.cBa

        (Bergmann et al., 1996)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        cactunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (4)