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General Information
Symbol
Dmel\armUAS.cWa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of White
FlyBase ID
FBal0086716
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-arm
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A KpnI/NotI arm cDNA fragment is expressed under the control of UASt regulatory sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of armScer\UAS.cWa under the control of Scer\GAL4nub.PU does not have a wing margin bristle phenotype in adult flies.

Expression of armScer\UAS.cWa under the control of Scer\GAL4en.PU results in ectopic bristles on the wing margin.

When armScer\UAS.cWa is driven by Scer\GAL4en-e16E ectopic wing margin bristles are see in the wing blade.

Expression of armScer\UAS.cWa under the control of Scer\GAL4en-e16E induces excess veins and bristles in the posterior wing blade. The extra veins concentrate around the posterior crossvein. Expression of armScer\UAS.cWa under the control of Scer\GAL4GMR.PF results in rough eyes and the loss of interommatidial bristles.

Expression of armScer\UAS.cWa under the control of Scer\GAL4arm.PS in arm2/+ embryos derived from homozygous arm2 female germline clones leads to a slight loss of denticles. Overexpression of armScer\UAS.cWa under the control of Scer\GAL4Bx-MS1096 results in ectopic wing vein formation and the formation of margin bristles in the wing blade.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

Scer\GAL4en.PU, armUAS.cWa has visible phenotype, enhanceable by Traf4[+]/Traf43

Scer\GAL4en-e16E, armUAS.cWa has visible phenotype, enhanceable by sggM11/sgg[+]

NOT Enhanced by
Statement
Reference

Scer\GAL4en-e16E, armUAS.cWa has visible phenotype, non-enhanceable by CadNM19

Scer\GAL4en-e16E, armUAS.cWa has visible phenotype, non-enhanceable by kelDE1

Suppressed by
NOT suppressed by
Statement
Reference

Scer\GAL4en-e16E, armUAS.cWa has visible phenotype, non-suppressible by CadNM19

Scer\GAL4en-e16E, armUAS.cWa has visible phenotype, non-suppressible by kelDE1

Phenotype Manifest In
Enhanced by
Statement
Reference

Scer\GAL4en-e16E, armUAS.cWa has wing phenotype, enhanceable by nkd2

Scer\GAL4en-e16E, armUAS.cWa has wing phenotype, enhanceable by shg1

Scer\GAL4en-e16E, armUAS.cWa has wing phenotype, enhanceable by ds55

NOT Enhanced by
Statement
Reference

Scer\GAL4en-e16E, armUAS.cWa has wing phenotype, non-enhanceable by CadNM19

Scer\GAL4en-e16E, armUAS.cWa has wing phenotype, non-enhanceable by kelDE1

Suppressed by
Statement
Reference
NOT suppressed by
Statement
Reference

Scer\GAL4en-e16E, armUAS.cWa has wing phenotype, non-suppressible by CadNM19

Scer\GAL4en-e16E, armUAS.cWa has wing phenotype, non-suppressible by kelDE1

Other
Additional Comments
Genetic Interactions
Statement
Reference

The wing margin bristle defects characteristic for meru1 mutant flies cannot be exacerbated further by Scer\GAL4nub.PU-driven expression armScer\UAS.cWa.

The ectopic wing margin bristle phenotype caused by expression of armScer\UAS.cWa under the control of Scer\GAL4en.PU is enhanced by Traf43/+.

The eye phenotype caused by expression of armScer\UAS.cWa under the control of Scer\GAL4GMR.PF is suppressed by dshb117 and wgl-17 and enhanced by sggM11. The phenotype caused by expression of armScer\UAS.cWa under the control of Scer\GAL4en-e16E is dominantly suppressed by wgl-17. Also, wing margin bristles are lost between veins 4 and 5 in these flies. The extra bristle phenotype caused by expression of armScer\UAS.cWa under the control of Scer\GAL4en-e16E is enhanced by one copy of sggM11, while the vein abnormalities are suppressed in these flies.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
armScer\UAS.cWa
armUAS.cWa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of White
Secondary FlyBase IDs
    References (7)