FB2025_01 , released February 20, 2025
Allele: Dmel\Sps1UAS.cAa
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General Information
Symbol
Dmel\Sps1UAS.cAa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Alsina
FlyBase ID
FBal0086754
Feature type
allele
Associated gene
Dmel\Sps1
Associated Insertion(s)
Carried in Construct
P{UAS-Sps1.A}
Also Known As
UAS-selD
Key Links
Transgenic product class
wild_type
(Alsina et al., 1998)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Alsina et al., 1998)
Mutagen
in vitro construct
(Alsina et al., 1998)
Progenitor genotype
Carried in construct
P{UAS-Sps1.A}
Cytology
Description

UAS regulatory sequences drive expression of a cDNA fragment encoding the complete open reading frame of SelD.

(Alsina et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Sps1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of SelDScer\UAS.cAa under the control of Scer\GAL4D42 reduces mean life span compared to controls.

      (Morey et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      Sps1UAS.cAa/Scer\GAL4GMR.PF is a non-suppressor of visible phenotype of rohs.sev1

      (Morey et al., 2001)
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Sps1UAS.cAa/Scer\GAL4GMR.PF is a non-suppressor of eye phenotype of rohs.sev1

      (Morey et al., 2001)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Sps1UAS.cAa/Scer\GAL469B rescues Sps1k11320

      (Alsina et al., 1998)
      Partially rescues

      Sps1UAS.cAa/Scer\GAL4GMR.PF partially rescues Sps1k11320

      (Morey et al., 2001)
      Comments

      The addition of SelDScer\UAS.cAa (driven by Scer\GAL4GMR.PF) to SelDk11320, sevS11.T:Hsap\MYC flies partially reduces the suppressive effect of the SelDk11320 allele on the sevS11.T:Hsap\MYC eye phenotype.

      (Morey et al., 2001)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      SelDScer\UAS.cAa
      SelDUAS.cAa
      Sps1UAS.cAa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Alsina
      (Alsina et al., 1998)
      Secondary FlyBase IDs
        References (3)