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General Information
Symbol
Dmel\NakUAS.cCa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Chien
FlyBase ID
FBal0086794
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Full length Nak is expressed under the control of UASt regulatory sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The number of dendritic endpoints of dorsal dendritic arborisation neurons is increased compared to controls in larvae expressing NakScer\UAS.cCa under the control of Scer\GAL4109(2)80.

Embryos expressing NakScer\UAS.cCa under the control of Scer\GAL4sca-537.4 show transformation of neurons to sheath cells in the chordotonal organs. Overexpression of NakScer\UAS.cCa under the control of Scer\GAL4sca-537.4 in adult sensory organs produces cell fate transformations in the bristles of the head, notum and wing margin. The mutant bristles sometimes contain two hairs and two sockets, or sometimes contain two sockets but no hair. Other phenotypes are characterised by four sockets, or one hair and three sockets. Neurons are missing under these mutant bristles.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

NakUAS.cCa, Scer\GAL4sca-537.4 has visible phenotype, enhanceable by numb[+]/numb1

NOT Suppressor of
Phenotype Manifest In
Enhanced by
Statement
Reference
NOT Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of NakScer\UAS.cCa does not suppress the reduction in the number of dendritic endpoints of dorsal dendritic arborisation neurons which is seen in larvae expressing NrgY1185D.Scer\UAS under the control of Scer\GAL4elav-C155.

The phenotype produced by overexpression of NakScer\UAS.cCa under the control of Scer\GAL4sca-537.4 is enhanced if the flies are also heterozygous for numb1. The cell fate transformation phenotypes produced by overexpression of either numbScer\UAS.cWa or NakScer\UAS.cCa in the adult sensory organs are suppressed in flies expressing both numbScer\UAS.cWa and NakScer\UAS.cCa in the adult sensory organs under the control of Scer\GAL4sca-109-68.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of NakScer\UAS.cCa under the control of Scer\GAL4elav-C155 rescues the dendritic defects seen in the dorsal dendritic arborisation neurons of Nak2 larvae.

Co-expression of NakScer\UAS.cCa rescues the dendritic defects seen in the dorsal dendritic arborisation neurons of larvae expressing NakdsRNA.Scer\UAS under the control of Scer\GAL4109(2)80.

Co-expression of NakScer\UAS.cCa rescues the dendritic defects seen in the dorsal dendritic arborisation neurons of larvae expressing NakdsRNA.Scer\UAS under the control of Scer\GAL4elav-C155.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
NakScer\UAS.cCa
NakUAS.cCa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Chien
Secondary FlyBase IDs
    References (2)