Allele Avic\GFP^S65T.Drs

General Information
Symbol	Avic\GFP^S65T.Drs	Species	A. victoria
Name		FlyBase ID	FBal0086834
Feature type	allele	Associated gene	Avic\GFP

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Ferrandon et al., 1998)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: Drs promoter sequences drive expression of the S65T version of Avic\GFP. 800bp of Drs downstream sequences are fused downstream of the Avic\GFP coding region. (Ferrandon et al., 1998)
Carried in construct	P{Drs-GFP.JM802} (Chiu et al., 2005, Vodovar et al., 2005, Ferrandon et al., 1998, Ha et al., 2005, Ligoxygakis et al., 2002, Landis et al., 2004, Tzou et al., 2000, Scherfer et al., 2006, Wang et al., 2006, Zaidman-Remy et al., 2006, McGettigan et al., 2005, Stramer et al., 2008, Ryu et al., 2004, Han et al., 2004)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Avic\GFP^S65T.Drs GFP^S65T.Drs
Name Synonym
Secondary FlyBase IDs

References ( 15 )
Research paper	Stramer et al., 2008, EMBO Rep. 9(5): 465--471 Gene induction following wounding of wild-type versus macrophage-deficient Drosophila embryos. [FBrf0205363] Scherfer et al., 2006, Dev. Biol. 295(1): 156--163 The Toll immune-regulated Drosophila protein Fondue is involved in hemolymph clotting and puparium formation. [FBrf0192416] Wang et al., 2006, EMBO J. 25(20): 5005--5014 Sensing of Gram-positive bacteria in Drosophila: GNBP1 is needed to process and present peptidoglycan to PGRP-SA. [FBrf0194406] Zaidman-Remy et al., 2006, Immunity 24(4): 463--473 The Drosophila amidase PGRP-LB modulates the immune response to bacterial infection. [FBrf0190838] Chiu et al., 2005, Dev. Biol. 288(1): 60--72 dUbc9 negatively regulates the Toll-NF-kappa B pathways in larval hematopoiesis and drosomycin activation in Drosophila. [FBrf0190102] McGettigan et al., 2005, Insect Biochem. Mol. Biol. 35(7): 741--754 Insect renal tubules constitute a cell-autonomous immune system that protects the organism against bacterial infection. [FBrf0187746] Vodovar et al., 2005, Proc. Natl. Acad. Sci. U.S.A. 102(32): 11414--11419 Drosophila host defense after oral infection by an entomopathogenic Pseudomonas species. [FBrf0188279] Han et al., 2004, Insect Mol. Biol. 13(3): 323--327 The moleskin gene product is essential for Caudal-mediated constitutive antifungal Drosomycin gene expression in Drosophila epithelia. [FBrf0179241] Landis et al., 2004, Proc. Natl. Acad. Sci. U.S.A. 101(20): 7663--7668 Similar gene expression patterns characterize aging and oxidative stress in Drosophila melanogaster. [FBrf0179295] Ryu et al., 2004, Mol. Cell. Biol. 24(1): 172--185 The homeobox gene Caudal regulates constitutive local expression of antimicrobial peptide genes in Drosophila epithelia. [FBrf0167895] Ligoxygakis et al., 2002, Science 297(5578): 114--116 Activation of Drosophila Toll during fungal infection by a blood serine protease. [FBrf0151487] Tzou et al., 2000, Immunity 13(5): 737--748 Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia. [FBrf0132355] Ferrandon et al., 1998, EMBO J. 17(5): 1217--1227 A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway. [FBrf0100810]
Supplementary material	Ha et al., 2005, Science 310(5749): A direct role for dual oxidase in Drosophila gut immunity. [FBrf0191535] Ha et al., 2005, Dev. Cell 8(1): [title not yet available] [FBrf0191548]

Allele Avic\GFPS65T.Drs

Allele Avic\GFP^S65T.Drs