Allele Dmel\zip^Ebr

General Information
Symbol	Dmel\zip^Ebr	Species	D. melanogaster
Name		FlyBase ID	FBal0088529
Feature type	allele	Associated gene	Dmel\zip
Also Known As	zipE(br), zip^E(br)

Map ( GBrowse )
Allele class
Mutagen
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References point mutation 2R:20,884,587..20,884,587 evidence=experimental na_change=G20884587A pr_change=R316H\|zip-PB,R361H\|zip-PA,R276H\|zip-PC,R321H\|z ip-PD reported_na_change=G14374A reported_pr_change=R276H (Halsell et al., 2000)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Amino acid replacement: R277H. (Halsell and Kiehart, 2000) Nucleotide substitution: G14374A. Amino acid replacement: R276H. Nucleotide coordinates are relative to the sequence record U35816. Amino acid coordinates are relative to the transcript published in FBrf0052857. (Halsell et al., 2000)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| recessive (Baumann, 2004, Halsell and Kiehart, 1998, Halsell et al., 2000, Bayer et al., 2003) partially lethal - majority live (with zip^33-1) (Bayer et al., 2003) visible (with zip^33-1) (Bayer et al., 2003) visible (with zip⁰²⁹⁵⁷) (Mizuno et al., 2002)
Phenotype Manifest In
	eye (with zip⁰²⁹⁵⁷) (Baumann, 2004) leg (with zip^33-1) (Bayer et al., 2003) pigment cell (with zip⁰²⁹⁵⁷) (Baumann, 2004) retina (with zip⁰²⁹⁵⁷) (Baumann, 2004) rhabdomere (with zip⁰²⁹⁵⁷) (Baumann, 2004) wing (with zip⁰²⁹⁵⁷) (Baumann, 2004, Mizuno et al., 2002)
Detailed Description
	Statement Reference zip^Ebr/zip⁰²⁹⁵⁷ transheterozygotes are viable but have malformed wings with varying degrees of severity. Mutants also have rough eyes. In these retina the Mysoin-II system is disorganised . Some rhabdomeres have gaps along their lengths. Moreover, the rhabdomeres are not as straight as in wild-type, but appear to meander slightly. At the retinal floor of mutants, the hexagonal arrangement of the pigment cell pedicels exhibit irregularities, moreover, the retinal floor is not completely flattened but wrinkled in some areas. (Baumann, 2004) zip^Ebr/zip^33-1 animals have a severe leg malformation phenotype. (Bayer et al., 2003) About 70% of zip^Ebr/zip⁰²⁹⁵⁷ adults have malformed wings. (Mizuno et al., 2002) Mutants die as late embryos or early larvae. (Halsell et al., 2000) Lethality acts post-embryonically. (Halsell and Kiehart, 1998)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement Reference Rho1^72BH, zip^Ebr has visible \| dominant phenotype, suppressible by Mbs³ (Mizuno et al., 2002) Rho1^72O, zip^Ebr has visible \| dominant phenotype, suppressible \| partially by Mbs³ (Mizuno et al., 2002) RhoGEF2⁰⁴²⁹¹, zip^Ebr has visible \| dominant phenotype, suppressible by Mbs³ (Mizuno et al., 2002) rok², zip^Ebr has visible \| dominant phenotype, suppressible by Mbs³ (Mizuno et al., 2002) zip⁰²⁹⁵⁷/zip^Ebr has visible phenotype, suppressible \| partially by Mbs³/Mbs[+] (Mizuno et al., 2002)
Enhancer of
Statement Reference zip[+]/zip^Ebr is an enhancer of visible \| dominant phenotype of br¹ (Chen et al., 2004) zip[+]/zip^Ebr is an enhancer of visible \| dominant phenotype of Sb^63b (Chen et al., 2004) zip[+]/zip^Ebr is an enhancer of visible \| dominant phenotype of Sb⁷⁰ (Chen et al., 2004)
Suppressor of
Statement Reference zip[+], zip^Ebr, Scer\GAL4[-] is a suppressor of lethal \| maternal effect \| embryonic stage phenotype of Mbs³/Df(3L)th117, Mbs^EP3727 (Mizuno et al., 2002) zip[+], zip^Ebr, Scer\GAL4[-] is a suppressor of lethal \| maternal effect \| embryonic stage phenotype of Mbs^EP3727/Df(3L)th117, Mbs³ (Mizuno et al., 2002) zip[+]/zip^Ebr is a suppressor of lethal \| embryonic stage phenotype of Scer\GAL4^arm.PS, rok^Scer\UAS.cMa (Mizuno et al., 2002) zip^Ebr is a suppressor of lethal \| recessive \| larval stage phenotype of Moe^G0323 (Speck et al., 2003)
Other
Statement Reference +/Df(1)ct-J4, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) +/Df(2R)Jp4, zip^Ebr has visible \| dominant phenotype (Halsell et al., 2000) +/Df(2R)M41A4, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) +/Df(3L)st4, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) +/In(2R)bw^VDe2LCy^R, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(1)64c18/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(1)A113/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(1)ct4b1/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(1)g/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(1)HA85/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(1)HF396/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(1)JC70/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(1)RA2/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(1)r-D1/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(1)sc-J4/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(1)v-L15/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(1)v-N48/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(2L)30A-C/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(2L)cl-h3/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(2L)H20/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(2L)J39/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(2L)JS32/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(2L)osp29/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(2L)sc19-5/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(2L)TE29Aa-11/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(2L)TW50/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(2R)B5/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(2R)bw^VDe2LPx^KR/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(2R)CX1/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(2R)Jp1/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(2R)Jp8, zip^Ebr has partially lethal - majority die \| dominant phenotype (Halsell and Kiehart, 1998) Df(2R)Jp8/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998, Halsell et al., 2000) Df(2R)nap1/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(2R)or-BR6/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(2R)PC4/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(2R)vg-C/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(3L)81k19/+, zip^Ebr has partially lethal - majority die \| dominant phenotype (Halsell and Kiehart, 1998) Df(3L)81k19/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(3L)AC1/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(3L)Cat/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(3L)GN24/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(3L)HR119/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(3L)HR370/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(3L)M21/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(3L)Pc-MK/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(3L)rdgC-co2/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(3L)st7/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(3L)st-b11/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(3L)W10/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Df(3R)ea/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) E(br)65^Ebr65, zip[+]/zip^Ebr has visible \| dominant phenotype (Ward et al., 2003) E(br)65^Ebr65/E(br)65[+], zip^Ebr has visible phenotype (Ward et al., 2003) E(br)121^Ebr121, zip[+]/zip^Ebr has visible \| dominant phenotype (Ward et al., 2003) E(br)121^Ebr121/E(br)121[+], zip^Ebr has visible phenotype (Ward et al., 2003) E(br)160[+]/E(br)160^Ebr160, zip^Ebr has visible phenotype (Ward et al., 2003) E(br)160^Ebr160, zip[+]/zip^Ebr has visible \| dominant phenotype (Ward et al., 2003) E(br)444[+]/E(br)444^Ebr444, zip^Ebr has visible phenotype (Ward et al., 2003) E(br)444^Ebr444, zip[+]/zip^Ebr has visible \| dominant phenotype (Ward et al., 2003) E(zip)12-5[+]/E(zip)12-5^12-5, zip^Ebr has visible phenotype (Bayer et al., 2003) E(zip)12-5^12-5, zip[+]/zip^Ebr has visible \| dominant phenotype (Bayer et al., 2003) E(zip)18-5[+]/E(zip)18-5^18-5, zip^Ebr has visible phenotype (Bayer et al., 2003) E(zip)18-5^18-5, zip[+]/zip^Ebr has visible \| dominant phenotype (Bayer et al., 2003) E(zip)31-6^31-6, zip[+]/zip^Ebr has visible \| dominant phenotype (Bayer et al., 2003) E(zip)31-6^31-6/E(zip)31-6[+], zip^Ebr has visible phenotype (Bayer et al., 2003) In(2LR)Px⁴/+, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Rho1[+]/Rho1^Ebr246, zip^Ebr has visible phenotype (Ward et al., 2003) Rho1^12-6, zip[+]/zip^Ebr has viable \| reduced phenotype (Bayer et al., 2003) Rho1^12-6, zip[+]/zip^Ebr has visible \| dominant phenotype (Bayer et al., 2003) Rho1^12-6, zip^Ebr has viable \| reduced phenotype (Bayer et al., 2003) Rho1^12-6/Rho1[+], zip^Ebr has visible phenotype (Bayer et al., 2003) Rho1^72BH, zip^Ebr has visible \| dominant phenotype (Mizuno et al., 2002) Rho1^72BH/Rho1[+], zip^Ebr has visible \| dominant phenotype (Mizuno et al., 2002) Rho1^72F, zip[+]/zip^Ebr has visible \| dominant phenotype (Halsell et al., 2000) Rho1^72F, zip^Ebr has visible \| dominant phenotype (Halsell et al., 2000) Rho1^72O, zip[+]/zip^Ebr has visible \| dominant phenotype (Halsell et al., 2000) Rho1^72O, zip^Ebr has visible \| dominant phenotype (Halsell et al., 2000, Mizuno et al., 2002) Rho1^72O/Rho1[+], zip^Ebr has visible \| dominant phenotype (Mizuno et al., 2002) Rho1^E3.10, zip[+]/zip^Ebr has partially lethal - majority die \| dominant phenotype (Halsell et al., 2000) Rho1^E3.10, zip[+]/zip^Ebr has partially lethal - majority live phenotype (Halsell and Kiehart, 1998) Rho1^E3.10, zip[+]/zip^Ebr has visible \| dominant phenotype (Halsell et al., 2000, Halsell and Kiehart, 1998) Rho1^E3.10, zip^Ebr has partially lethal - majority die \| dominant phenotype (Halsell et al., 2000) Rho1^E3.10, zip^Ebr has visible \| dominant phenotype (Halsell et al., 2000) Rho1^E3.10/Rho1[+], zip^Ebr has partially lethal - majority die \| dominant phenotype (Halsell and Kiehart, 1998) Rho1^E3.10/Rho1[+], zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Rho1^Ebr233, zip[+]/zip^Ebr has visible \| dominant phenotype (Ward et al., 2003) Rho1^Ebr233/Rho1[+], zip^Ebr has visible phenotype (Ward et al., 2003) Rho1^Ebr246, zip[+]/zip^Ebr has visible \| dominant phenotype (Ward et al., 2003) Rho1^J3.8, zip[+]/zip^Ebr has partially lethal - majority die \| dominant phenotype (Halsell et al., 2000) Rho1^J3.8, zip[+]/zip^Ebr has partially lethal - majority live phenotype (Halsell and Kiehart, 1998) Rho1^J3.8, zip[+]/zip^Ebr has visible \| dominant phenotype (Halsell et al., 2000, Halsell and Kiehart, 1998) Rho1^J3.8, zip^Ebr has partially lethal - majority die \| dominant phenotype (Halsell et al., 2000) Rho1^J3.8, zip^Ebr has visible \| dominant phenotype (Halsell et al., 2000) Rho1^J3.8/Rho1[+], zip^Ebr has partially lethal - majority die \| dominant phenotype (Halsell and Kiehart, 1998) Rho1^J3.8/Rho1[+], zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) RhoGEF2^1.1, zip[+]/zip^Ebr has visible \| dominant phenotype (Bayer et al., 2003, Halsell et al., 2000) RhoGEF2^1.1, zip^Ebr has visible \| dominant phenotype (Halsell et al., 2000) RhoGEF2^1.1/RhoGEF2[+], zip^Ebr has visible phenotype (Bayer et al., 2003) RhoGEF2^4.1, zip[+]/zip^Ebr has visible \| dominant phenotype (Bayer et al., 2003, Halsell et al., 2000) RhoGEF2^4.1, zip^Ebr has visible \| dominant phenotype (Halsell et al., 2000) RhoGEF2^4.1/RhoGEF2[+], zip^Ebr has visible phenotype (Bayer et al., 2003) RhoGEF2^11-3, zip[+]/zip^Ebr has visible \| dominant phenotype (Bayer et al., 2003) RhoGEF2^11-3/RhoGEF2[+], zip^Ebr has visible phenotype (Bayer et al., 2003) RhoGEF2⁰⁴²⁹¹, zip[+]/zip^Ebr has visible \| dominant phenotype (Halsell et al., 2000, Bayer et al., 2003) RhoGEF2⁰⁴²⁹¹, zip^Ebr has visible \| dominant phenotype (Halsell et al., 2000, Mizuno et al., 2002) RhoGEF2⁰⁴²⁹¹/RhoGEF2[+], zip^Ebr has visible \| dominant phenotype (Mizuno et al., 2002) RhoGEF2⁰⁴²⁹¹/RhoGEF2[+], zip^Ebr has visible phenotype (Bayer et al., 2003) rok[+]/rok¹, zip^Ebr has visible phenotype (Bayer et al., 2003) rok[+]/rok², zip^Ebr has visible \| dominant phenotype (Mizuno et al., 2002) rok[+]/rok², zip^Ebr has visible phenotype (Bayer et al., 2003) rok¹, zip[+]/zip^Ebr has visible \| dominant phenotype (Bayer et al., 2003) rok², zip[+]/zip^Ebr has visible \| dominant phenotype (Bayer et al., 2003) rok², zip^Ebr has visible \| dominant phenotype (Mizuno et al., 2002) Sb[+]/Sb⁷⁰, zip^Ebr has visible phenotype (Bayer et al., 2003) Sb[+]/Sb^Ebr20, zip^Ebr has visible phenotype (Ward et al., 2003) Sb[+]/Sb^Ebr48, zip^Ebr has visible phenotype (Ward et al., 2003) Sb[+]/Sb^Ebr448, zip^Ebr has visible phenotype (Ward et al., 2003) Sb[+]/Sb^Ebr536, zip^Ebr has visible phenotype (Ward et al., 2003) Sb⁷⁰, zip[+]/zip^Ebr has visible \| dominant phenotype (Bayer et al., 2003) Sb^Ebr20, zip[+]/zip^Ebr has visible \| dominant phenotype (Ward et al., 2003) Sb^Ebr48, zip[+]/zip^Ebr has visible \| dominant phenotype (Ward et al., 2003) Sb^Ebr448, zip[+]/zip^Ebr has visible \| dominant phenotype (Ward et al., 2003) Sb^Ebr536, zip[+]/zip^Ebr has visible \| dominant phenotype (Ward et al., 2003) Sb^Ebr623, zip[+]/zip^Ebr has visible \| dominant phenotype (Ward et al., 2003) Sb^Ebr623/Sb[+], zip^Ebr has visible phenotype (Ward et al., 2003) Tm1[+]/Tm1^eg9, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Tm1^eg9, zip[+]/zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) Tm1^er4, zip[+]/zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) vkg[+]/vkg⁰¹²⁰⁹, zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) vkg⁰¹²⁰⁹, zip[+]/zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) vkg^k09511, zip[+]/zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998) vkg^k09511/vkg[+], zip^Ebr has visible \| dominant phenotype (Halsell and Kiehart, 1998)
Phenotype Manifest In
NOT Enhanced by
Statement Reference zip^Ebr has phenotype, non-enhanceable by Eip74EF^DL-1 (Halsell and Kiehart, 1998) zip^Ebr has phenotype, non-enhanceable by Eip74EF^neo24 (Halsell and Kiehart, 1998) zip^Ebr has phenotype, non-enhanceable by Khc⁸ (Halsell and Kiehart, 1998) zip^Ebr has phenotype, non-enhanceable by l(2)52Fb^D2.33 (Halsell and Kiehart, 1998) zip^Ebr has phenotype, non-enhanceable by l(2)52Fc^D8.13 (Halsell and Kiehart, 1998) zip^Ebr has phenotype, non-enhanceable by l(2)52Fd^E3.27 (Halsell and Kiehart, 1998) zip^Ebr has phenotype, non-enhanceable by l(2)52Fe^E6.17 (Halsell and Kiehart, 1998)
Suppressed by
Statement Reference Rho1^72BH, zip^Ebr has wing phenotype, suppressible by Mbs³ (Mizuno et al., 2002) Rho1^72O, zip^Ebr has wing phenotype, suppressible \| partially by Mbs³ (Mizuno et al., 2002) RhoGEF2⁰⁴²⁹¹, zip^Ebr has wing phenotype, suppressible by Mbs³ (Mizuno et al., 2002) rok², zip^Ebr has wing phenotype, suppressible by Mbs³ (Mizuno et al., 2002) zip⁰²⁹⁵⁷/zip^Ebr has wing phenotype, suppressible \| partially by Mbs³/Mbs[+] (Mizuno et al., 2002)
Enhancer of
Statement Reference zip[+]/zip^Ebr is an enhancer of leg phenotype of br¹ (Chen et al., 2004) zip[+]/zip^Ebr is an enhancer of leg phenotype of Sb^63b (Chen et al., 2004) zip[+]/zip^Ebr is an enhancer of leg phenotype of Sb⁷⁰ (Chen et al., 2004)
Other
Statement Reference +/Df(1)ct-J4, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) +/Df(1)ct-J4, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) +/Df(2R)Jp4, zip^Ebr has leg phenotype (Halsell et al., 2000) +/Df(2R)M41A4, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) +/Df(2R)M41A4, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) +/Df(3L)st4, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) +/Df(3L)st4, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) +/In(2R)bw^VDe2LCy^R, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) +/In(2R)bw^VDe2LCy^R, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(1)64c18/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(1)64c18/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(1)A113/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(1)A113/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(1)ct4b1/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(1)ct4b1/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(1)g/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(1)g/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(1)HA85/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(1)HA85/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(1)HF396/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(1)HF396/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(1)JC70/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(1)JC70/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(1)RA2/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(1)RA2/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(1)r-D1/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(1)r-D1/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(1)sc-J4/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(1)sc-J4/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(1)v-L15/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(1)v-L15/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(1)v-N48/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(1)v-N48/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2L)30A-C/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2L)30A-C/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2L)cl-h3/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2L)cl-h3/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2L)H20/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2L)H20/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2L)J39/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2L)J39/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2L)JS32/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2L)JS32/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2L)osp29/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2L)osp29/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2L)sc19-5/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2L)sc19-5/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2L)TE29Aa-11/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2L)TE29Aa-11/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2L)TW50/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2L)TW50/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2R)B5/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2R)B5/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2R)bw^VDe2LPx^KR/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2R)bw^VDe2LPx^KR/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2R)CX1/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2R)CX1/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2R)Jp1/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2R)Jp1/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2R)Jp8/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2R)Jp8/+, zip^Ebr has leg phenotype (Halsell et al., 2000) Df(2R)Jp8/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2R)nap1/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2R)nap1/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2R)or-BR6/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2R)or-BR6/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2R)PC4/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2R)PC4/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(2R)vg-C/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(2R)vg-C/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(3L)81k19/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(3L)81k19/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(3L)AC1/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(3L)AC1/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(3L)Cat/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(3L)Cat/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(3L)GN24/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(3L)GN24/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(3L)HR119/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(3L)HR119/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(3L)HR370/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(3L)HR370/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(3L)M21/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(3L)M21/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(3L)Pc-MK/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(3L)Pc-MK/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(3L)rdgC-co2/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(3L)rdgC-co2/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(3L)st7/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(3L)st7/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(3L)st-b11/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(3L)st-b11/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(3L)W10/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(3L)W10/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Df(3R)ea/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Df(3R)ea/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) E(br)65^Ebr65, zip[+]/zip^Ebr has leg phenotype (Ward et al., 2003) E(br)65^Ebr65, zip^Ebr has leg phenotype (Ward et al., 2003) E(br)121^Ebr121, zip[+]/zip^Ebr has leg phenotype (Ward et al., 2003) E(br)121^Ebr121, zip^Ebr has leg phenotype (Ward et al., 2003) E(br)160^Ebr160, zip[+]/zip^Ebr has leg phenotype (Ward et al., 2003) E(br)160^Ebr160, zip^Ebr has leg phenotype (Ward et al., 2003) E(br)444^Ebr444, zip[+]/zip^Ebr has leg phenotype (Ward et al., 2003) E(br)444^Ebr444, zip^Ebr has leg phenotype (Ward et al., 2003) E(zip)12-5^12-5, zip[+]/zip^Ebr has leg phenotype (Bayer et al., 2003) E(zip)12-5^12-5, zip[+]/zip^Ebr has wing phenotype (Bayer et al., 2003) E(zip)12-5^12-5, zip^Ebr has leg phenotype (Bayer et al., 2003) E(zip)12-5^12-5, zip^Ebr has wing phenotype (Bayer et al., 2003) E(zip)18-5^18-5, zip[+]/zip^Ebr has leg phenotype (Bayer et al., 2003) E(zip)18-5^18-5, zip[+]/zip^Ebr has wing phenotype (Bayer et al., 2003) E(zip)18-5^18-5, zip^Ebr has leg phenotype (Bayer et al., 2003) E(zip)18-5^18-5, zip^Ebr has wing phenotype (Bayer et al., 2003) E(zip)31-6^31-6, zip[+]/zip^Ebr has leg phenotype (Bayer et al., 2003) E(zip)31-6^31-6, zip[+]/zip^Ebr has wing phenotype (Bayer et al., 2003) E(zip)31-6^31-6, zip^Ebr has leg phenotype (Bayer et al., 2003) E(zip)31-6^31-6, zip^Ebr has wing phenotype (Bayer et al., 2003) In(2LR)Px⁴/+, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) In(2LR)Px⁴/+, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Rho1^12-6, zip[+]/zip^Ebr has leg phenotype (Bayer et al., 2003) Rho1^12-6, zip[+]/zip^Ebr has wing phenotype (Bayer et al., 2003) Rho1^12-6, zip^Ebr has leg phenotype (Bayer et al., 2003) Rho1^12-6, zip^Ebr has wing phenotype (Bayer et al., 2003) Rho1^72BH, zip^Ebr has wing phenotype (Mizuno et al., 2002) Rho1^72BH/Rho1[+], zip^Ebr has wing phenotype (Mizuno et al., 2002) Rho1^72F, zip[+]/zip^Ebr has leg phenotype (Halsell et al., 2000) Rho1^72F, zip[+]/zip^Ebr has wing phenotype (Halsell et al., 2000) Rho1^72F, zip[+]/zip^Ebr has wing vein phenotype (Halsell et al., 2000) Rho1^72F, zip^Ebr has leg phenotype (Halsell et al., 2000) Rho1^72F, zip^Ebr has wing phenotype (Halsell et al., 2000) Rho1^72F, zip^Ebr has wing vein phenotype (Halsell et al., 2000) Rho1^72O, zip[+]/zip^Ebr has leg phenotype (Halsell et al., 2000) Rho1^72O, zip^Ebr has leg phenotype (Halsell et al., 2000) Rho1^72O, zip^Ebr has wing phenotype (Mizuno et al., 2002) Rho1^72O/Rho1[+], zip^Ebr has wing phenotype (Mizuno et al., 2002) Rho1^E3.10, zip[+]/zip^Ebr has femur phenotype (Halsell et al., 2000, Halsell and Kiehart, 1998) Rho1^E3.10, zip[+]/zip^Ebr has leg phenotype (Halsell et al., 2000) Rho1^E3.10, zip[+]/zip^Ebr has tibia phenotype (Halsell et al., 2000, Halsell and Kiehart, 1998) Rho1^E3.10, zip[+]/zip^Ebr has wing phenotype (Halsell et al., 2000) Rho1^E3.10, zip^Ebr has femur phenotype (Halsell et al., 2000) Rho1^E3.10, zip^Ebr has leg phenotype (Halsell et al., 2000) Rho1^E3.10, zip^Ebr has tibia phenotype (Halsell et al., 2000) Rho1^E3.10, zip^Ebr has wing phenotype (Halsell et al., 2000) Rho1^E3.10/Rho1[+], zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Rho1^E3.10/Rho1[+], zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Rho1^Ebr233, zip[+]/zip^Ebr has leg phenotype (Ward et al., 2003) Rho1^Ebr233, zip^Ebr has leg phenotype (Ward et al., 2003) Rho1^Ebr246, zip[+]/zip^Ebr has leg phenotype (Ward et al., 2003) Rho1^Ebr246, zip^Ebr has leg phenotype (Ward et al., 2003) Rho1^J3.8, zip[+]/zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Rho1^J3.8, zip[+]/zip^Ebr has leg phenotype (Halsell et al., 2000) Rho1^J3.8, zip[+]/zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Rho1^J3.8, zip^Ebr has leg phenotype (Halsell et al., 2000) Rho1^J3.8/Rho1[+], zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Rho1^J3.8/Rho1[+], zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) RhoGEF2^1.1, zip[+]/zip^Ebr has leg phenotype (Bayer et al., 2003, Halsell et al., 2000) RhoGEF2^1.1, zip^Ebr has leg phenotype (Halsell et al., 2000, Bayer et al., 2003) RhoGEF2^4.1, zip[+]/zip^Ebr has femur phenotype (Halsell et al., 2000) RhoGEF2^4.1, zip[+]/zip^Ebr has leg phenotype (Bayer et al., 2003, Halsell et al., 2000) RhoGEF2^4.1, zip[+]/zip^Ebr has tibia phenotype (Halsell et al., 2000) RhoGEF2^4.1, zip[+]/zip^Ebr has wing phenotype (Halsell et al., 2000) RhoGEF2^4.1, zip^Ebr has femur phenotype (Halsell et al., 2000) RhoGEF2^4.1, zip^Ebr has leg phenotype (Halsell et al., 2000, Bayer et al., 2003) RhoGEF2^4.1, zip^Ebr has tibia phenotype (Halsell et al., 2000) RhoGEF2^4.1, zip^Ebr has wing phenotype (Halsell et al., 2000) RhoGEF2^11-3, zip[+]/zip^Ebr has leg phenotype (Bayer et al., 2003) RhoGEF2^11-3, zip[+]/zip^Ebr has wing phenotype (Bayer et al., 2003) RhoGEF2^11-3, zip^Ebr has leg phenotype (Bayer et al., 2003) RhoGEF2^11-3, zip^Ebr has wing phenotype (Bayer et al., 2003) RhoGEF2⁰⁴²⁹¹, zip[+]/zip^Ebr has leg phenotype (Halsell et al., 2000, Bayer et al., 2003) RhoGEF2⁰⁴²⁹¹, zip^Ebr has leg phenotype (Halsell et al., 2000, Bayer et al., 2003) RhoGEF2⁰⁴²⁹¹, zip^Ebr has wing phenotype (Mizuno et al., 2002) RhoGEF2⁰⁴²⁹¹/RhoGEF2[+], zip^Ebr has wing phenotype (Mizuno et al., 2002) rok[+]/rok², zip^Ebr has wing phenotype (Mizuno et al., 2002) rok¹, zip[+]/zip^Ebr has leg phenotype (Bayer et al., 2003) rok¹, zip[+]/zip^Ebr has wing phenotype (Bayer et al., 2003) rok¹, zip^Ebr has leg phenotype (Bayer et al., 2003) rok¹, zip^Ebr has wing phenotype (Bayer et al., 2003) rok², zip[+]/zip^Ebr has leg phenotype (Bayer et al., 2003) rok², zip^Ebr has leg phenotype (Bayer et al., 2003) rok², zip^Ebr has wing phenotype (Mizuno et al., 2002) Sb⁷⁰, zip[+]/zip^Ebr has wing phenotype (Bayer et al., 2003) Sb⁷⁰, zip^Ebr has wing phenotype (Bayer et al., 2003) Sb^Ebr20, zip[+]/zip^Ebr has leg phenotype (Ward et al., 2003) Sb^Ebr20, zip^Ebr has leg phenotype (Ward et al., 2003) Sb^Ebr48, zip[+]/zip^Ebr has leg phenotype (Ward et al., 2003) Sb^Ebr48, zip^Ebr has leg phenotype (Ward et al., 2003) Sb^Ebr448, zip[+]/zip^Ebr has leg phenotype (Ward et al., 2003) Sb^Ebr448, zip^Ebr has leg phenotype (Ward et al., 2003) Sb^Ebr536, zip[+]/zip^Ebr has leg phenotype (Ward et al., 2003) Sb^Ebr536, zip^Ebr has leg phenotype (Ward et al., 2003) Sb^Ebr623, zip[+]/zip^Ebr has leg phenotype (Ward et al., 2003) Sb^Ebr623, zip^Ebr has leg phenotype (Ward et al., 2003) Tm1[+]/Tm1^eg9, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Tm1[+]/Tm1^eg9, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Tm1^eg9, zip[+]/zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Tm1^eg9, zip[+]/zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) Tm1^er4, zip[+]/zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) Tm1^er4, zip[+]/zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) vkg[+]/vkg⁰¹²⁰⁹, zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) vkg[+]/vkg⁰¹²⁰⁹, zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) vkg⁰¹²⁰⁹, zip[+]/zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) vkg⁰¹²⁰⁹, zip[+]/zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) vkg^k09511, zip[+]/zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) vkg^k09511, zip[+]/zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998) vkg^k09511/vkg[+], zip^Ebr has femur phenotype (Halsell and Kiehart, 1998) vkg^k09511/vkg[+], zip^Ebr has tibia phenotype (Halsell and Kiehart, 1998)
Additional Comments
Genetic Interactions
Statement Reference The frequency of the malformed leg phenotype seen in Sb^63b/+ heterozygotes (8%) is increased if the flies are also heterozygous for zip^Ebr (63%). The frequency of the malformed leg phenotype seen in Sb⁷⁰/+ heterozygotes (7%) is increased if the flies are also heterozygous for zip^Ebr (96%). The frequency of the malformed leg phenotype seen in br¹/Y males (1%) is increased if the flies are also heterozygous for zip^Ebr (56%). (Chen et al., 2004) zip^Ebr shows no interaction with sqh^unspecified (assayed in terms of a malformed leg phenotype). zip^Ebr shows a strong interaction (at least 50% of double heterozygotes have at least one malformed leg) with the following mutations: RhoGEF2^11-3, E(zip)12-5^12-5 and Rho1^12-6. zip^Ebr shows a moderate interaction (25-49% of double heterozygotes have at least one malformed leg) with the following mutations: E(zip)18-5^18-5. zip^Ebr shows a weak interaction (5-24% of double heterozygotes have at least one malformed leg) with the following mutations: E(zip)31-6^31-6. zip^Ebr shows a strong interaction (at least 50% of double heterozygotes have at least one malformed wing) with the following mutations: rok¹, Sb⁷⁰, RhoGEF2^11-3, E(zip)12-5^12-5, Rho1^12-6 and E(zip)31-6^31-6. zip^Ebr shows a moderate interaction (25-49% of double heterozygotes have at least one malformed wing) with the following mutations: E(zip)18-5^18-5. (Bayer et al., 2003) The fraction of flies showing a malformed leg phenotype in at least one leg, for zip^Ebr in double heterozygous combination with one of the following alleles is - Sb^Ebr20: 46%, Sb^Ebr48: 30%, Sb^Ebr228: 14%, Sb^Ebr448: 57%, Sb^Ebr536: 33%, Sb^Ebr623: 26%, Rho1^Ebr233: 93%, Rho1^Ebr246: 83%, bs^Ebr292: 2%, E(br)24^Ebr24: 9%, E(br)65^Ebr65: 67%, E(br)155^Ebr155: 7%, E(br)165^Ebr165: 6%, E(br)333^Ebr333: 4%, E(br)72^Ebr72: 4%, E(br)121^Ebr121: 82%, E(br)160^Ebr160: 20%, E(br)187^Ebr187: 6%, E(br)420^Ebr420: 15% and E(br)444^Ebr444: 84%. (Ward et al., 2003) The lethality of Mbs mutant embryos derived from Mbs^EP3727/Df(3L)th117 females mated to Mbs³/+ males is suppressed by zip^Ebr/+. (Mizuno et al., 2002) 27% of RhoGEF2^4.1/zip^Ebr double heterozygotes have a malformed leg phenotype, which shows variable expressivity. In less severe cases, there is a dent in the femur or tibia. Flies with malformed legs often also show wing defects. Weak phenotypes include a broadening of the wing blade and folding back of the distal portion of the wing blade. In the most severe cases, wings are greatly reduced in size. 38% of RhoGEF2⁰⁴²⁹¹/zip^Ebr double heterozygotes have a malformed leg phenotype. 33% of RhoGEF2^1.1/zip^Ebr double heterozygotes have a malformed leg phenotype. 100% of Rho1^J3.8/zip^Ebr double heterozygotes have a malformed leg phenotype. 100% of Rho1^E3.10/zip^Ebr double heterozygotes have a malformed leg phenotype, which shows variable expressivity. In more severe cases, a dent and twisting of the femur is apparent, along with shortening and thickening of the tibia. Notching of the posterior region of the wing blade is also seen. 96% of Rho1^72F/zip^Ebr double heterozygotes have a malformed leg phenotype. Wing defects are also seen. Weak phenotypes include a broadening of the wing blade and folding back of the distal portion of the wing blade. In more severe cases, wings lacking adhesion between the wing blade bilayer and any apparent wing venation are seen. 92% of Rho1^72O/zip^Ebr double heterozygotes have a malformed leg phenotype. 90% of Df(2R)Jp4/zip^Ebr double heterozygotes have a malformed leg phenotype. 98% of Df(2R)Jp8/zip^Ebr double heterozygotes have a malformed leg phenotype. (Halsell et al., 2000) Produces malformed phenotype when in double heterozygosis with second site zip non-complementing mutants. Shows a higher level of penetrance with second site non-complementers than does zip^mhc-c6.1. (Halsell and Kiehart, 1998)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	E(br)¹ (Gotwals and Fristrom, 1991) zip^E(br) (Ward et al., 2003, Farkas et al., 2007) zip^ebr (Chen et al., 2004) zip^Ebr (Hawley and Gilliland, 2006) zipE(br) (Farkas et al., 2003, Farkas et al., 2006) zipEbr (Swain and Kiehart, 2002)
Name Synonym
Secondary FlyBase IDs

References ( 17 )
Research paper	Baumann, 2004, Dev. Biol. 269(2): 519--533 Spatial pattern of nonmuscle myosin-II distribution during the development of the Drosophila compound eye and implications for retinal morphogenesis. [FBrf0174531] Chen et al., 2004, Curr. Biol. 14(4): 309--313 Rho-LIM kinase signaling regulates ecdysone-induced gene expression and morphogenesis during Drosophila metamorphosis. [FBrf0174477] Bayer et al., 2003, Genetics 165(3): 1417--1432 Genetic interactions between the RhoA and Stubble-stubbloid loci suggest a role for a type II transmembrane serine protease in intracellular signaling during Drosophila imaginal disc morphogenesis. [FBrf0167640] Speck et al., 2003, Nature 421(6918): 83--87 Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity. [FBrf0155521] Ward et al., 2003, Genetics 165(3): 1397--1415 Genetic modifier screens in Drosophila demonstrate a role for Rho1 signaling in ecdysone-triggered imaginal disc morphogenesis. [FBrf0167639] Mizuno et al., 2002, Development 129(5): 1215--1223 Drosophila myosin phosphatase and its role in dorsal closure. [FBrf0144821] Halsell et al., 2000, Genetics 155(3): 1253--1265 Genetic analysis demonstrates a direct link between rho signaling and nonmuscle myosin function during Drosophila morphogenesis. [FBrf0128483] Halsell and Kiehart, 1998, Genetics 148(4): 1845--1863 Second-site noncomplementation identifies genomic regions required for Drosophila nonmuscle myosin function during morphogenesis. [FBrf0102325] Gotwals and Fristrom, 1991, Genetics 127: 747--759 Three neighboring genes interact with the Broad-Complex and the Stubble-stubbloid locus to affect imaginal disc morphogenesis in Drosophila. [FBrf0054179]
Review	Hawley and Gilliland, 2006, Genetics 174(1): 5--15 Sometimes the result is not the answer: The truths and the lies that come from using the complementation test. [FBrf0194489]
Abstract	Farkas et al., 2007, Europ. Dros. Res. Conf. 20: G029 CHROMATIN ACCESS OF TRANSCRIPTION AND REMODELLING FACTORS IS REGULATED BY CYTOSKELETAL PROTEINS DURING ECDYSONE-TRIGGERED CELL DEATH IN DROSOPHILA. [FBrf0199865] Farkas et al., 2006, A. Dros. Res. Conf. 47: 747B Modulation of chromatin access for transcription and remodelling factors by cytoskeletal proteins during ecdysone-triggered cell death of Drosophila salivary glands. [FBrf0189425] Farkas et al., 2003, Europ. Dros. Res. Conf. 18: C22 Chromatin access of Drosophila transcription and remodelling factors regulated by cytoskeletal proteins. [FBrf0161719] Swain and Kiehart, 2002, A. Dros. Res. Conf. 43: 235A A Genetic Screen for Novel Myosin II and Rho Pathway Interactors. [FBrf0146483] Williams et al., 2001, A. Dros. Res. Conf. 42: 233B Molecular genetic analysis reveals the role of non-muscle myosin II activity and localization during morphogenesis. [FBrf0134243] Halsell and Kiehart, 2000, A. Dros. Res. Conf. 41: 452A Nonmuscle myosin-II requires Rho signal transduction to drive morphogenetic cell shape change. [FBrf0126613] Halsell and Kiehart, 1999, A. Dros. Res. Conf. 40: 323A Morphogenesis driven by nonmuscle myosin-II requires function of the Rho signal transduction pathway. [FBrf0106598]

Allele Dmel\zipEbr

Allele Dmel\zip^Ebr