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General Information
Symbol
Dmel\hhEP3521
Species
D. melanogaster
Name
FlyBase ID
FBal0089235
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{EP} insertion 215bp downstream of the hh translation initiation codon. The P{EP} element is oriented such that expression from the element results in overexpression of hh.

Inserted 500bp downstream from the start of the hh first exon.

P{EP} insertion 364bp upstream of the hh transcription start site.

P{EP} insertion at +215bp of the transcription unit.

Insertion components
P{EP}hhEP3521
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

ventral nerve cord commissures in stage 17 hhEP3521; Scer\GAL4sca-4512 embryos are fused and/or 'fuzzy'.

Expression of hhEP3521 under the control of Scer\GAL4ey.PH results in eyes that are somewhat reduced in size. Flies expressing hhEP3521 under the control of Scer\GAL4hs.2sev have wild-type eyes. Flies expressing hhEP3521 under the control of Scer\GAL4en-e16E have wild-type wings.

Expression of hhEP3521 under the control of Scer\GAL4sca-537.4 results in additional scutellar macrochaetae and short and thickened shaft morphology.

Expression of hhEP3521 using Scer\GAL4bi-omb-Gal4 or Scer\GAL4dpp.blk1 results in lethality. Expression of hhEP3521 using Scer\GAL4hs.2sev results in semi-lethality, occasional adult escapers having rough or reduced eyes.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT suppressed by
Statement
Reference
Suppressor of
Statement
Reference
Phenotype Manifest In
NOT suppressed by
Statement
Reference
Suppressor of
Statement
Reference

hhEP3521/Scer\GAL4ey.PH is a suppressor | partially of eye | ventral phenotype of L2

Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of CycEScer\UAS.cLa does not suppress the small eye phenotype caused by expression of hhEP3521 under the control of Scer\GAL4ey.PH.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (9)