Allele Dmel\if^{ΔGFFNR.Scer\UAS}

General Information
Symbol	Dmel\if^{ΔGFFNR.Scer\UAS}	Species	D. melanogaster
Name		FlyBase ID	FBal0090411
Feature type	allele	Associated gene	Dmel\if

Allele class
Mutagen	in vitro construct - regulatory fusion, in vitro construct - deletion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - deletion (Martin-Bermudo et al., 1998) in vitro construct - regulatory fusion (Martin-Bermudo et al., 1998)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: A mutant form of if, lacking the highly conserved GFFNR motif, is expressed under the control of Scer\UAS regulatory sequences. (Martin-Bermudo et al., 1998)
Carried in construct	P{UAS-if.ΔGFFNR} (Martin-Bermudo et al., 1998, Tanentzapf and Brown, 2006)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference Does not produce larger or ectopic muscle attachments when expressed under the control of both Scer\GAL4^how-24B and Scer\GAL4^twi.PG in a wild-type background. (Martin-Bermudo et al., 1998)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement Reference Scer\GAL4^how-24B, if^{ΔGFFNR.Scer\UAS}, Scer\GAL4^how-24B is a suppressor of muscle attachment site \| germline clone \| embryonic stage phenotype of Df(3L)79a, rhea^{R367A.Ubi-p63E} (Tanentzapf and Brown, 2006) Scer\GAL4^how-24B, if^{ΔGFFNR.Scer\UAS}, Scer\GAL4^how-24B is a suppressor of presumptive embryonic/larval muscle system \| germline clone \| embryonic stage phenotype of Df(3L)79a, rhea^{R367A.Ubi-p63E} (Tanentzapf and Brown, 2006)
Additional Comments
Genetic Interactions
Statement Reference Expression of if[ΔGFFNR.Scer\UAS] under the control of Scer\GAL4[how-24B] rescues the late-muscle-detachment phenotype of embryos expressing rhea[R367A.Ubi-p63E] in a Df(3L)79a mutant background. (Tanentzapf and Brown, 2006)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Partially rescues	Scer\GAL4^twi.PG, Scer\GAL4^how-24B, if^{ΔGFFNR.Scer\UAS}, Scer\GAL4^how-24B partially rescues if^B4 (Martin-Bermudo et al., 1998)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	if^{ΔGFFNR.Scer\UAS} if^ΔGFFNR.UAS
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Tanentzapf and Brown, 2006, Nat. Cell Biol. 8(6): 601--606 An interaction between integrin and the talin FERM domain mediates integrin activation but not linkage to the cytoskeleton. [FBrf0193338] Martin-Bermudo et al., 1998, J. Cell Biol. 141(4): 1073--1081 Modulation of integrin activity is vital for morphogenesis. [FBrf0102666]

Allele Dmel\ifΔGFFNR.Scer\UAS

Allele Dmel\if^{ΔGFFNR.Scer\UAS}