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General Information
Symbol
Dmel\Med17
Species
D. melanogaster
Name
FlyBase ID
FBal0090594
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

C31614806A

Amino acid change:

P741T | Med-PA; P667T | Med-PB; P741T | Med-PC

Reported amino acid change:

P715T

Comment:

Site of nucleic acid difference in mutant inferred by FlyBase based on reported amino acid change.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: P715T.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous adults do not have any obvious phenotypic abnormalities. 98% of embryos derived from homozygous females hatch.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference
Other
Phenotype Manifest In
Enhancer of
Statement
Reference

Med17/Med[+] is an enhancer of phenotype of dpphr4

Other
Additional Comments
Genetic Interactions
Statement
Reference

Animals derived from homozygous Med17 females mated to dpphr4/+ males show strong lethality (less than 5% of the expected number survive).

The severe loss of climbing ability in a negative geotaxis assay which is seen in Scgδ840 mutants is suppressed if the flies are also carrying Med17/+.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (3)