Ectopic expression of E2fScer\UAS.cNa
under the regulation of Scer\GAL4sca-537.4
results in an increase in cell number in some abdominal hemisegments. In addition transformation of NB6-4a to NB6-4t is observed at low penetrance (13%).
The average cell doubling time in wing disc cells expressing E2fScer\UAS.cNa
under the control of Scer\GAL4Act5C.PP
is shortened to 9.5 hours (compared to 12 hours for wild-type cells). The average duration of cell cycle phases in these cells is: G1 = 1.4 hours, S = 4.6 hours and G2 = 3.5 hours (wild-type values are G1 = 3.4 hours, S = 4.4 hours and G2 = 4.2 hours). The number of posterior cells in wing discs expressing E2fScer\UAS.cNa
under the control of Scer\GAL4en-e16E
is higher than that of wild-type discs.