The GMC-1 cells in numb796 mutant embryos symmetrically divide into two sib cells rather than a sib and an RP2 cell.
In numb796 mutants, the GMC-1 of the RP2/sib lineage symmetrically divides into two sib cells instead of an RP2 and a sib. Penetrance is restricted to ~50% of hemisegments.
GMC-1 of the RP2/sib lineage divides symmetrically to produce two RP2sib cells in mutant embryos.
The Malpighian tubules do not take up their normal positions in numb796 mutant embryos and the tubules lack tip cells.
In mutant embryos Malpighian tubule tip cells are missing except in about 8% embryos, where one or two of the four tubules are allocated normally. However, there is no change in the final number of tubule cells. The distinction between the number of cells in the anterior and posterior tubules is also unaffected.
In about 27% of hemisegments in mutant embryos, a RP2 to RP2sib transformation is seen. This division produces two cells of unequal size, but both cells behave like sib neurons.
27% of mutant hemisegments show an RP2 to RP2sib cell fate transformation. The number of eve-positive CQ neurons is increased. 11% of hemisegments show an RP2 to RP2sib cell fate transformation in numb1/numb796 embryos. 62% of hemisegments show an RP2 to RP2sib cell fate transformation in numb796/Df(2L)30A-C embryos.