FB2025_01 , released February 20, 2025
Allele: Dmel\Polr2BSM
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General Information
Symbol
Dmel\Polr2BSM
Species
D. melanogaster
Name
FlyBase ID
FBal0091643
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Carried in construct
Cytology
Description

Construct: Nucleotide substitution: A2966T. This substitution is shared by in vivo-generated strong suppressors. Nucleotide substitution: G3065A. This substitution is shared by in vivo-generated mild suppressors.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement
Reference

Polr2BSM has phenotype, suppressible by Polr2AK1

Suppressor of
Statement
Reference

Polr2BSM is a suppressor of phenotype of Polr2A120

Polr2BSM is a suppressor of phenotype of Polr2AK1

NOT Suppressor of
Statement
Reference

Polr2BSM is a non-suppressor of phenotype of Polr2A12

Additional Comments
Genetic Interactions
Statement
Reference

Behaves as a strong suppressor but not a mild suppressor. Flies carrying RpII215K1, RpII140A5 and RpII140SM are viable: i.e. RpII215K1 and RpII140SM show reciprocal suppression.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to rescue
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Polr2BSM
RpII140SM
Name Synonyms
Secondary FlyBase IDs
    References (1)