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General Information
Symbol
Dmel\ApcS76
Species
D. melanogaster
Name
FlyBase ID
FBal0091897
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    point mutation
    Nucleotide change:

    G28839298A

    Amino acid change:

    W488term | Apc-PA; W488term | Apc-PB; W488term | Apc-PC

    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference

    Amino acid replacement: W488term.

    Nucleotide substitution: G1671A.

    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Ectopic photoreceptor apoptosis is seen in the developing eyes of ApcS76/ApcQ8 pupae, beginning at around 35 hours after puparium formation (APF) and peaking at 42 hours APF. This timing is identical to that of photoreceptor apoptosis occurring at the periphery of the developing eye in wild-type pupae.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Suppressed by
    Statement
    Reference
    Phenotype Manifest In
    Suppressed by
    Statement
    Reference
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Ectopic photoreceptor apoptosis in the developing eyes of ApcS76/ApcQ8 pupae is greatly reduced by Df(3L)H99/+.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    ApcS76
    Name Synonyms
    Secondary FlyBase IDs
      References (2)