FB2025_01 , released February 20, 2025
Allele: Dmel\tkvUAS.Tag:HA
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General Information
Symbol
Dmel\tkvUAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0092479
Feature type
allele
Associated gene
Dmel\tkv
Associated Insertion(s)
Carried in Construct
P{UAS-tkv.T:HA1}
Also Known As
UAS-Tkv-HA, UAS-tkv
Key Links
Transgenic product class
wild_type
(Haerry et al., 1998)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Haerry et al., 1998)
Mutagen
in vitro construct
(Haerry et al., 1998)
Progenitor genotype
Carried in construct
P{UAS-tkv.T:HA1}
Cytology
Description

Full length wild-type tkv, tagged with Tag:HA is expressed under the control of UAS regulatory sequences.

(Haerry et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
tkv
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing tkvScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4vg.PM have essentially wild-type wings.

      (Bennett et al., 2003)

      Larvae expressing tkvScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4A9 have small wing discs. Adult wings show loss of wing vein L4. Flies expressing tkvScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4en-e16E show truncation of the distal part of wing vein L4 and lack most of vein L5.

      (Haerry et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      NOT Suppressor of
      Phenotype Manifest In
      Enhancer of
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Coexpression of tkvScer\UAS.T:Ivir\HA1 and gbbScer\UAS.cKa enhances the Scer\GAL4A9>gbbScer\UAS.cKa wing vein phenotype so that a higher percentage of wings have extensive amounts of wing vein tissue.

      (Bangi and Wharton, 2006)

      The modest wing overgrowth phenotype caused by expression of putScer\UAS.cMa under the control of Scer\GAL4vg.PM is enhanced by co-expression of tkvScer\UAS.T:Ivir\HA1.

      (Bennett et al., 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4elav.PLu/tkvUAS.Tag:HA rescues tkv1/tkv8

      (McCabe et al., 2004)
      Comments

      Expression of tkvScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4elav.PLu in the neurons rescues neuromuscular junction size in tkv1/tkv8 mutants.

      (McCabe et al., 2004)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      tkvScer\UAS.T:Ivir\HA1
      tkvUAS.T:Ivir\HA1
      tkvUAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (9)