FB2025_01 , released February 20, 2025
Allele: Dmel\numbunspecified
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General Information
Symbol
Dmel\numbunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0092594
Feature type
allele
Associated gene
Dmel\numb
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In

        embryonic Malpighian tubule tip cell

        (Ainsworth et al., 2000)

        larval RP2 motor neuron

        (Wai et al., 1999)

        muscle cell of abdominal 2 dorsal acute muscle 1

        (Park et al., 1998)

        muscle cell of abdominal 2 dorsal acute muscle 2

        (Park et al., 1998)

        muscle cell of abdominal 2 dorsal oblique muscle 1

        (Park et al., 1998)

        muscle cell of abdominal 2 dorsal oblique muscle 2

        (Park et al., 1998)

        muscle cell of abdominal 3 dorsal acute muscle 1

        (Park et al., 1998)

        muscle cell of abdominal 3 dorsal acute muscle 2

        (Park et al., 1998)

        muscle cell of abdominal 3 dorsal oblique muscle 1

        (Park et al., 1998)

        muscle cell of abdominal 3 dorsal oblique muscle 2

        (Park et al., 1998)

        muscle cell of abdominal 4 dorsal acute muscle 1

        (Park et al., 1998)

        muscle cell of abdominal 4 dorsal acute muscle 2

        (Park et al., 1998)

        muscle cell of abdominal 4 dorsal oblique muscle 1

        (Park et al., 1998)

        muscle cell of abdominal 4 dorsal oblique muscle 2

        (Park et al., 1998)

        muscle cell of abdominal 5 dorsal acute muscle 1

        (Park et al., 1998)

        muscle cell of abdominal 5 dorsal acute muscle 2

        (Park et al., 1998)

        muscle cell of abdominal 5 dorsal oblique muscle 1

        (Park et al., 1998)

        muscle cell of abdominal 5 dorsal oblique muscle 2

        (Park et al., 1998)

        muscle cell of abdominal 6 dorsal acute muscle 1

        (Park et al., 1998)

        muscle cell of abdominal 6 dorsal acute muscle 2

        (Park et al., 1998)

        muscle cell of abdominal 6 dorsal oblique muscle 1

        (Park et al., 1998)

        muscle cell of abdominal 6 dorsal oblique muscle 2

        (Park et al., 1998)

        muscle cell of abdominal 7 dorsal acute muscle 1

        (Park et al., 1998)

        muscle cell of abdominal 7 dorsal acute muscle 2

        (Park et al., 1998)

        muscle cell of abdominal 7 dorsal oblique muscle 1

        (Park et al., 1998)

        muscle cell of abdominal 7 dorsal oblique muscle 2

        (Park et al., 1998)
        Detailed Description
        Statement
        Reference

        Mutant embryos lack Malpighian tubule tip cells, but the tubules contain a completely wild-type number of cells.

        (Ainsworth et al., 2000)

        In an unspecified Deficiency that uncovers numb, RP2 neurons are occasionally transformed into a sib fate.

        (Wai et al., 1999)

        Muscle DA1 is present as a myosin-expressing muscle fiber in only 8% of hemisegments, DA2 is present in 5.5%, DO1 is present in 21% and DO2 is present in 15% of hemisegments in mutant embryos. Subdivision of the somatic, visceral and cardiac muscle progenitors appears to be normal.

        (Park et al., 1998)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        numbunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (4)