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General Information
Symbol
Dmel\msnUAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Su
FlyBase ID
FBal0092606
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-msn, UAS-Misshapen
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of an msn cDNA.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

photoreceptor cell R1 & axon, with Scer\GAL4GMR.PF

photoreceptor cell R2 & axon, with Scer\GAL4GMR.PF

photoreceptor cell R3 & axon, with Scer\GAL4GMR.PF

photoreceptor cell R4 & axon, with Scer\GAL4GMR.PF

photoreceptor cell R5 & axon, with Scer\GAL4GMR.PF

photoreceptor cell R6 & axon, with Scer\GAL4GMR.PF

Detailed Description
Statement
Reference

Expression of msnScer\UAS.cSa in the wing, under the control of Scer\GAL4Bx-MS1096 results in mild or undetectable phenotypic changes.

Over expression of msnScer\UAS.cSa in the eye driven by Scer\GAL4hs.2sev causes a rough eye phenotype and reveals typical polarity defects in ommatidia.

Expression of msnScer\UAS.cSa under the control of Scer\GAL4GMR.PF causes R1-R6 photoreceptor cell growth cones to show an "early stop" phenotype. Some growth cones terminate before others resulting in an uneven termination pattern within the lamina. The phenotype is dose dependent.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
NOT suppressed by
Statement
Reference

Scer\GAL4elav-C155, msnUAS.cSa has photoreceptor & axon phenotype, non-suppressible by dock04723

Enhancer of
NOT Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference

Expression of msnScer\UAS.cSa does not suppress the increase in circulating lamellocytes seen when ND75KK108222 is expressed under the control of Scer\GAL4Antp-10.

Simultaneous expression of msnScer\UAS.cSa with lkb1Scer\UAS.cLa (both under the control of Scer\GAL4Bx-MS1096 strongly enhances the lkb1Scer\UAS.cLa phenotype, resulting in severe disruption in the structure and size of the wing blades.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

When msn-CT.Scer\UAS is driven by Scer\GAL469B in msn102 or msn172 embryos, 100% of rescued embryos survive to pupal stages, the dorsal closure phenotype seen in these mutants is also rescued.

Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
msnScer\UAS.cSa
msnUAS.cSa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Su
Secondary FlyBase IDs
    References (13)