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General Information
Symbol
Dmel\fzUAS.N
Species
D. melanogaster
Name
FlyBase ID
FBal0092979
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-fzDN
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

cDNA sequence nucleotides 589-1413 (FBrf0050626) is expressed from UASt regulatory sequences. This includes coding sequence for the N-terminal 272 amino acids which encompasses the first transmembrane domain and the first two residues of the first intracellular loop, and was put in frame with a heterologous RWL peptide followed by a stop codon. Contains 9 nucleotides of 5' UTR.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expressing fzUAS.N under the control of Scer\GAL4HCH.Hand fails to induce defects in heart morphology or ostia formation in embryos.

Expression of fzScer\UAS.N under the control of Scer\GAL4dome-PG14 results in mislocalisation of hemocyte precursors from the medullary zone into the cortical zone of the lymph gland, and differentiation of hemocyte precursors into plasmatocytes is observed.

Expression of fzScer\UAS.N under the control of Scer\GAL4Antp-10 does not cause a reduction in the number of cells of the posterior signalling center of the lymph gland.

Expression of fzScer\UAS.N under the control of Scer\GAL4lz-gal4 does not affect the number of crystal cells.

Expression of fzScer\UAS.N under the control of Scer\GAL4fkh.PZ results in salivary gland guidance defects; a large portion of the salivary gland curves towards the central nervous system, with the curving beginning early, as the gland migrates along the circular visceral mesoderm.

Expression of fzScer\UAS.N under the control of Scer\GAL4dpp.blk1 has no effect on furrow formation in the eye disc.

Expression of fzScer\UAS.N under the control of Scer\GAL4da.G32 results in a phenotype similar to that produced by overexpression of sgg.

No RP2/sib lineage defect is seen in embryos expressing fzScer\UAS.N under the control of Scer\GAL4da.G32.

When expression is driven by Scer\GAL4hs.2sev, the two chiral forms of ommatidia are intermixed in the dorsal and ventral half of the eye. When expression is driven by Scer\GAL469B, posterior wing margin and anterior bristles are partially lost. This can be rescued by co-expression with fzScer\UAS.cZa.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

Scer\GAL469B, fzUAS.N has visible phenotype, enhanceable by dsh3

Scer\GAL469B, fzUAS.N has visible phenotype, enhanceable by arm1

Suppressed by
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of fzScer\UAS.N and fz2ECD.GPI.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4dome-PG14 results in mislocalisation of hemocyte precursors from the medullary zone into the cortical zone of the lymph gland, and differentiation of hemocyte precursors into plasmatocytes is observed.

The phenotype caused by expression of fzScer\UAS.N using Scer\GAL469B can be rescued by co-expression with fz2Scer\UAS.cZa. This phenotype can be dominantly suppressed by wgl-17. When expression is driven by Scer\GAL469B, ectopic wing bristle phenotype of fz2Scer\UAS.cZa is suppressed.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
fzScer\UAS.N
fzUAS.N
Name Synonyms
Secondary FlyBase IDs
    References (7)