Open Close
General Information
Symbol
Dmel\fz2UAS.cZa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Zhang
FlyBase ID
FBal0092981
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Frizzled2, UAS-Dfz2
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
cDNA sequence which includes the entire open reading frame is expressed from UASt regulatory sequences.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
fz2Scer\UAS.cZa, Scer\GAL4en-e16E embryos lose type 1 denticles. This is seen in all embryos, although at times, one or two segments remain unaffected.
Overexpression of fz2Scer\UAS.cZa does not affect the wild-type denticle pattern.
When expression is driven by Scer\GAL469B, supernumerary stout mechanosensory bristles appear one or two cell diameters from the normal row, supernumerary slender mechanosensory bristles and chemosensory bristles appear one or more rows from the wing margin and supernumerary posterior hairs appear in the interior of the posterior wing. Ectopic bristles are more numerous near the margin, and the type of ectopic bristle formed correlates with its distance from the margin; those close to the margin are of the stout mechanosensory type, whereas those further distant are of the slender mechanosensory or chemosensory types. When expression is driven by Scer\GAL4hs.2sev, ommatidia are normally oriented and otherwise unaffected. Suppresses wing margin loss phenotype of fz2Scer\UAS.N. Ectopic bristle induction suppressed by fz2Scer\UAS.N.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference
Phenotype Manifest In
Enhanced by
NOT Enhanced by
Suppressed by
NOT suppressed by
Enhancer of
NOT Enhancer of
Statement
Reference
fz2UAS.cZa/Scer\GAL4e22c is a non-enhancer of phenotype of wgl-17
Suppressor of
Statement
Reference
fz2UAS.cZa/Scer\GAL4e22c is a suppressor | partially of phenotype of wgPE2
NOT Suppressor of
Statement
Reference
fz2UAS.cZa/Scer\GAL4e22c is a non-suppressor of phenotype of wgl-17
Additional Comments
Genetic Interactions
Statement
Reference
Over expression of fz2Scer\UAS.cZa and wgPE2.Scer\UAS driven by Scer\GAL4e22c produces uniformly naked cuticle.
The supernumerary wing bristle phenotypes can be suppressed by wgl-17. Suppresses wing margin loss phenotype of fzScer\UAS.N. Ectopic bristle induction suppressed by fzScer\UAS.N.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
fz2Scer\UAS.cZa
fz2UAS.cZa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Zhang
Secondary FlyBase IDs
    References (8)