The expression of fz2Scer\UAS.N
under the control of Scer\GAL4Mhc.PW
leads to the dorsal longitudinal indirect flight muscles exhibiting mitochondria defects, including abnormal morphology, sparse and collapsed cristae, and a significant decrease in electron density in electron microscopy images at 21 days post eclosion, as compared to controls.
is expressed in dorsal cluster neurons under the control of Scer\GAL4ato.3.6
the branching pattern in the adult medulla is disturbed, giving rise to an increased number of branches at the 3rd branching point of the grid-like structure.
Third instar larvae expressing fz2Scer\UAS.N
under the control of Scer\GAL4Mhc.PU
show a reduction in neuromuscular junction size compared to controls.
One copy of fz2Scer\UAS.N
has no effect on hemocyte proliferation in third instar larvae.
Expression of fz2Scer\UAS.N
under the control of Scer\GAL4fkh.PZ
results in salivary gland guidance defects; a large portion of the salivary gland curves towards the central nervous system, with the curving beginning early, as the gland migrates along the circular visceral mesoderm.
When expressed from Scer\GAL4ptc-559.1
the apical cells of the ovarian sheath remain clustered in the apical region of the ovary, indicating that they are not capable of basal migration.
Ectopic expression of fz2Scer\UAS.N
at the presumptive wing margin using Scer\GAL4C96
is associated with a fully penetrant mild wing margin defect.
When expression is driven by Scer\GAL4hs.2sev
, the two chiral forms of ommatidia are intermixed in the dorsal and ventral half of the eye. When expression is driven by Scer\GAL469B
, significant wing margin and bristle loss occurs, with reduction in wing size. When expression is driven by Scer\GAL469B
, ectopic wing bristle phenotype of fz2Scer\UAS.cZa