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General Information
Symbol
Dmel\tweEP613
Species
D. melanogaster
Name
FlyBase ID
FBal0093757
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
EP(2)0613
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{EP} insertion 9bp upstream of the twe translation initiation codon. The P{EP} element is oriented such that expression from the element should result in overexpression of twe.

The orientation of the P{EP} element is the same as the direction of twe transcription.

P{EP} insertion at -290bp relative to the start of the transcription unit.

Insertion components
P{EP}tweEP613
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of tweEP613 under the control of Scer\GAL4sca-537.4 results in potential shaft-to-socket transformations. Rarely, sensory organs with 4 sockets and no shaft are seen. Additional scutellar and dorsocentral macrochaetae are seen. Sensory organs with two sockets and two shafts, one socket and two shafts, no socket and one shaft and short and thickened shaft morphology are seen.

Male sterile but female fertile when transheterozygous with twe1.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhanced by
Statement
Reference
NOT suppressed by
Statement
Reference

Scer\GAL4sca-537.4, tweEP613 has visible phenotype, non-suppressible by H[+]/HE21

NOT Enhancer of
Suppressor of
NOT Suppressor of
Phenotype Manifest In
NOT Enhancer of
Suppressor of
NOT Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

The rough eye phenotype caused by expression of Hsap\MAPTV337M.Scer\UAS under the control of Scer\GAL4GMR.PF is suppressed by tweEP613.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Precise excision of the P{EP} element reverts the modifying effect of tweEP613 on the rough eye phenotype caused by expression of Hsap\MAPTV337M.Scer\UAS under the control of Scer\GAL4GMR.PF.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (8)