FlyBase Allele Report: Scer\GAL4[tim.PE]

Expression of Scer\GAL4^tim.PE is seen in cells near sensilla on the head capsule, thorax and abdomen of the adult. Expression of Scer\GAL4^tim.PE in seen within the abdominal portion of the adult midgut. Expression in the mouth is restricted to the posterior region.

(Kaneko and Hall, 2000)

Marker for

Reflects expression of

tim

(Chen et al., 2012, Ruiz et al., 2010, Helfrich-Forster et al., 2007, Hamasaka and Nassel, 2006, Kaneko and Hall, 2000, Emery et al., 1998)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Phenotypic Data

Phenotypic Class

behavior defective, with Scer\GAL80^Pdf.PS, sgg^EP1576

(Stoleru et al., 2007)

behavior defective, with sgg^EP1576

(Stoleru et al., 2007)

chemical sensitive, with slo^UAS.cGa

(Ghezzi et al., 2013)

circadian behavior defective, with Atx2^KK100423

(Zhang et al., 2013)

circadian behavior defective, with dom^HMC04203

(Liu et al., 2019)

circadian behavior defective, with dom^HMC04451

(Liu et al., 2019)

circadian behavior defective, with dom^HMS01855

(Liu et al., 2019)

circadian behavior defective, with dom^JF01502

(Liu et al., 2019)

circadian behavior defective, with Mocs2B^KK101263

(Marelja et al., 2018)

circadian behavior defective, with na^KK102435

(Lear et al., 2013)

circadian behavior defective, with Scer\GAL80^cry.PS, Shaw^{dsRNA.Sym.UAS.cHa}

(Hodge and Stanewsky, 2008)

circadian behavior defective, with Scer\GAL80^Pdf.PS, dom^HMC04203

(Liu et al., 2019)

circadian behavior defective, with Scer\GAL80^Pdf.PS, dom^HMC04451

(Liu et al., 2019)

circadian behavior defective, with unc79^KK102682

(Lear et al., 2013)

circadian behavior defective, with unc80^KK101371

(Lear et al., 2013)

circadian behavior defective | adult stage, with Hsap\KCNS2^D379E.UAS

(Smith et al., 2018)

circadian behavior defective | adult stage, with Hsap\KCNS2^UAS.cSa

(Smith et al., 2018)

circadian behavior defective | adult stage, with pn^HMC06185

(Chen et al., 2019)

circadian behavior defective | adult stage, with Scer\GAL80^Pdf.PS, pn^HMC06185

(Chen et al., 2019)

circadian behavior defective | adult stage, with Scer\GAL80^Pdf.PS, TFAM^JF02307

(Chen et al., 2019)

circadian behavior defective | adult stage, with Scer\GAL80^Pdf.PS, TFAM^UAS.cCa

(Chen et al., 2019)

circadian behavior defective | adult stage, with TFAM^JF02307

(Chen et al., 2019)

circadian behavior defective | adult stage, with TFAM^UAS.cCa

(Chen et al., 2019)

circadian behavior defective | adult stage, with Xvas\XhoI^{UASp.Tag:Mito(kdn),Tag:MYC}

(Chen et al., 2019)

circadian rhythm defective, with 5-HT1B^dsRNA.UAS

(Yuan et al., 2005, Yuan et al., 2005)

circadian rhythm defective, with 5-HT1B^UAS.cYa

(Yuan et al., 2005)

circadian rhythm defective, with Clk^{Δ.UAS.Tag:HA}

(Tanoue et al., 2004)

circadian rhythm defective, with cry^UAS.cEa

(Emery et al., 2000, Emery et al., 1998)

circadian rhythm defective, with ctrip^NIG.14656R

(Lamaze et al., 2011)

circadian rhythm defective, with ctrip^NIG.14656R, ctrip^NIG.17735R

(Lamaze et al., 2011)

circadian rhythm defective, with ctrip^NIG.17735R

(Lamaze et al., 2011)

circadian rhythm defective, with cyc^{Δ.UAS.Tag:MYC}

(Tanoue et al., 2004)

circadian rhythm defective, with dco^{K38R.UAS.cVa.Tag:MYC}

(Venkatesan et al., 2015)

circadian rhythm defective, with dco^{K38R.UAS.Tag:MYC,Tag:NLS(SV40-largeT)}

(Venkatesan et al., 2015)

circadian rhythm defective, with dco^{NLS-.UAS.Tag:MYC}

(Venkatesan et al., 2015)

circadian rhythm defective, with Scer\GAL80^cry.PS, Shaw^{dsRNA.Sym.UAS.cHa}

(Hodge and Stanewsky, 2008)

circadian rhythm defective, with Scer\GAL80^cry.PS, Shaw^{RA.UAS.Tag:FLAG}

(Hodge and Stanewsky, 2008)

circadian rhythm defective, with Scer\GAL80^Pdf.PS, sgg^EP1576

(Stoleru et al., 2005)

circadian rhythm defective, with Scer\GAL80^Pdf.PS, Shaw^{RA.UAS.Tag:FLAG}

(Hodge and Stanewsky, 2008)

circadian rhythm defective, with sgg^EP1576

(Stoleru et al., 2005)

circadian rhythm defective, with sgg^S9A.UAS

(Wolf et al., 2007)

circadian rhythm defective, with sgg^UAS.cBa

(Wolf et al., 2007, Yuan et al., 2005)

circadian rhythm defective, with Shaw^{RA.UAS.Tag:FLAG}

(Hodge and Stanewsky, 2008)

circadian rhythm defective, with shn^UAS.cMa

(Beckwith et al., 2013)

circadian rhythm defective, with tyf^G10872

(Lim et al., 2011)

circadian rhythm defective | adult stage, with cbt^UAS.Tag:FLAG

(Bartok et al., 2015)

circadian rhythm defective | adult stage, with NKCC^NIG.2509R

(Buhl et al., 2016)

circadian rhythm defective | adult stage, with NKCC^{UAS.Tag:FLAG,Tag:HA}

(Buhl et al., 2016)

circadian rhythm defective | adult stage, with qsm^dsRNA.UAS

(Buhl et al., 2016)

circadian rhythm defective | adult stage, with qsm^GD4817

(Buhl et al., 2016)

circadian rhythm defective | adult stage, with qsm^UAS.cCa

(Buhl et al., 2016)

circadian rhythm defective | adult stage, with Shaw^{dsRNA.Sym.UAS.cHa}

(Buhl et al., 2016)

circadian rhythm defective | adult stage, with Shaw^{RA.UAS.Tag:FLAG}

(Buhl et al., 2016)

circadian rhythm defective | conditional, with Spyo\Cas9^UAS.P2, per^{UAS.gRNAx4.pCFD6}

(Delventhal et al., 2019)

circadian rhythm defective | conditional, with Spyo\Cas9^UAS.P2, tim^{UAS.gRNAx3.pCFD6}

(Delventhal et al., 2019)

circadian rhythm defective | heat sensitive, with Actβ^JF03276, Scer\GAL80^Pdf.PS

(Beckwith et al., 2013)

circadian rhythm defective | heat sensitive, with Scer\GAL80^Pdf.PS, daw^KK110248

(Beckwith et al., 2013)

circadian rhythm defective | heat sensitive, with Scer\GAL80^Pdf.PS, dpp^HMS00011

(Beckwith et al., 2013)

circadian rhythm defective | heat sensitive, with Scer\GAL80^Pdf.PS, gbb^HMS01243

(Beckwith et al., 2013)

circadian rhythm defective | heat sensitive, with Scer\GAL80^Pdf.PS, mav^HMS01125

(Beckwith et al., 2013)

circadian rhythm defective | heat sensitive, with Scer\GAL80^Pdf.PS, myo^JF01717

(Beckwith et al., 2013)

circadian rhythm defective | heat sensitive, with Scer\GAL80^Pdf.PS, scw^KK109520

(Beckwith et al., 2013)

circadian rhythm defective | heat sensitive, with Scer\GAL80^Pdf.PS, shn⁷⁵⁶

(Beckwith et al., 2013)

decreased cell number | adult stage, with dom^HMC04451

(Liu et al., 2019)

decreased cell number | adult stage, with dom^JF01502

(Liu et al., 2019)

eclosion rhythm defective, with cyc^{Δ.UAS.Tag:MYC}

(Selcho et al., 2017)

eclosion rhythm defective, with dco^{L.UAS.Tag:MYC}

(Selcho et al., 2017)

eclosion rhythm defective, with dco^{S.UAS.Tag:MYC}

(Selcho et al., 2017)

eclosion rhythm defective, with lark^UAS.Tag:HA

(Schroeder et al., 2003)

eclosion rhythm defective, with Scer\GAL80^phm.1.2, cyc^{Δ.UAS.Tag:MYC}

(Selcho et al., 2017)

eclosion rhythm defective, with Scer\GAL80^phm.1.2, dco^{L.UAS.Tag:MYC}

(Selcho et al., 2017)

eclosion rhythm defective, with Scer\GAL80^phm.1.2, dco^{S.UAS.Tag:MYC}

(Selcho et al., 2017)

eclosion rhythm defective, with Scer\GAL80^phm.1.2, tim^UAS.cUa

(Selcho et al., 2017)

eclosion rhythm defective, with tim^UAS.cUa

(Selcho et al., 2017)

eclosion rhythm defective, with tor^GD14396

(Selcho et al., 2017)

increased cell death | progressive, with dco^{K38R.UAS.Tag:MYC}

(Means et al., 2015)

increased cell death | progressive, with spag^{dsRNA.UAS.cUa}

(Means et al., 2015)

lethal, with Alas^KK101189

(Mandilaras and Missirlis, 2012)

lethal, with CG17683^KK115708

(Mandilaras and Missirlis, 2012)

lethal, with Coprox^KK101688

(Mandilaras and Missirlis, 2012)

lethal, with Cul3^NIG.11861R

(Grima et al., 2012)

lethal, with Eip75B^GD1434

(Mandilaras and Missirlis, 2012)

lethal, with Fer1HCH^GD4853

(Mandilaras and Missirlis, 2012)

lethal, with Fer1HCH^KK110669

(Mandilaras and Missirlis, 2012)

lethal, with galla-1^KK101219

(Mandilaras and Missirlis, 2012)

lethal, with IscU^GD14694

(Marelja et al., 2018, Mandilaras and Missirlis, 2012)

lethal, with Pbgs^GD12588

(Mandilaras and Missirlis, 2012)

lethal, with Ppox^GD11772

(Mandilaras and Missirlis, 2012)

lethal, with tws^UAS.cGa

(Sathyanarayanan et al., 2004)

lethal, with Usp8^DN.UAS

(Luo et al., 2012)

lethal, with Usp8^dsRNA.2.UAS

(Luo et al., 2012)

lethal - all die before end of embryonic stage, with hid^UAS.cZa

(Stoleru et al., 2004)

locomotor behavior defective, with spag^{dsRNA.UAS.cUa}

(Means et al., 2015)

locomotor behavior defective | adult stage, with cbt^UAS.Tag:FLAG

(Bartok et al., 2015)

locomotor rhythm defective, with Bdbt^GD9337

(Fan et al., 2013)

locomotor rhythm defective, with Bdbt^KK102995

(Fan et al., 2013)

locomotor rhythm defective, with Cat^GD1291

(Mandilaras and Missirlis, 2012)

locomotor rhythm defective, with CG1358^KK109206

(Mandilaras and Missirlis, 2012)

locomotor rhythm defective, with CG4858^KK100349

(Mandilaras and Missirlis, 2012)

locomotor rhythm defective, with CG8043^KK107835

(Mandilaras and Missirlis, 2012)

locomotor rhythm defective, with CkIIα^UAS.cLa

(Lin et al., 2005)

locomotor rhythm defective, with Clk^{Δ.UAS.Tag:HA}

(Tanoue et al., 2004)

locomotor rhythm defective, with cry^{dsRNA.UAS.cPa}

(Picot et al., 2007)

locomotor rhythm defective, with Ctet\tetX^TNT-LC.UAS

(Kaneko et al., 2000)

locomotor rhythm defective, with ctrip^miRNA.UAS

(Sathyanarayanan et al., 2008)

locomotor rhythm defective, with cu^NIG.31299R

(Nagoshi et al., 2010)

locomotor rhythm defective, with Cul3^{K717R.UAS.GFP}

(Grima et al., 2012)

locomotor rhythm defective, with Cul3^{KR.Scer\UAS.Tag:FLAG}

(Grima et al., 2012)

locomotor rhythm defective, with Cul3^WT.UAS.GFP

(Grima et al., 2012)

locomotor rhythm defective, with Cul3^ΔC.UAS

(Grima et al., 2012)

locomotor rhythm defective, with cwo^dsRNA.UAS

(Lim et al., 2007)

locomotor rhythm defective, with cyc^VP16.UAS

(Kadener et al., 2008)

locomotor rhythm defective, with cyc^{Δ.UAS.Tag:MYC}

(Sehadova et al., 2009, Tanoue et al., 2004)

locomotor rhythm defective, with dco^{K38R.UAS.Tag:MYC}

(Fan et al., 2013, Muskus et al., 2007)

locomotor rhythm defective, with dco^{L.UAS.Tag:MYC}

(Muskus et al., 2007)

locomotor rhythm defective, with dco^{S.UAS.Tag:MYC}

(Muskus et al., 2007)

locomotor rhythm defective, with dco^{Tau.UAS.Tag:MYC}

(Fan et al., 2009)

locomotor rhythm defective, with Dcr-2^UAS.cDa, gw^HMS00105

(Zhang and Emery, 2013)

locomotor rhythm defective, with Dcr-2^UAS.cDa, gw^KK101472

(Zhang and Emery, 2013)

locomotor rhythm defective, with Dcr-2^UAS.cDa, Gαs^JF03255

(Zhang and Emery, 2013)

locomotor rhythm defective, with Dcr-2^UAS.cDa, Pka-C1^GL00038

(Zhang and Emery, 2013)

locomotor rhythm defective, with Dcr-2^UAS.cDa, Pka-C1^JF01188

(Zhang and Emery, 2013)

locomotor rhythm defective, with Dcr-2^UAS.cDa, Pka-C1^JF01218

(Zhang and Emery, 2013)

locomotor rhythm defective, with Dcr-2^UAS.cDa, Scer\GAL80^Pdf.PS, gw^KK101472

(Zhang and Emery, 2013)

locomotor rhythm defective, with dnc^UAS.cCa

(Zhang and Emery, 2013)

locomotor rhythm defective, with FeCH^KK108873

(Mandilaras and Missirlis, 2012)

locomotor rhythm defective, with Fer2LCH^GD6348

(Mandilaras and Missirlis, 2012)

locomotor rhythm defective, with Fer2LCH^KK103577

(Mandilaras and Missirlis, 2012)

locomotor rhythm defective, with fh^dsRNA.IR.UAS

(Mandilaras and Missirlis, 2012)

locomotor rhythm defective, with Fmr1^EP3517

(Dockendorff et al., 2002)

locomotor rhythm defective, with Fmr1^NE3-4

(Dockendorff et al., 2002)

locomotor rhythm defective, with Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}

(Kadener et al., 2006)

locomotor rhythm defective, with ITP^UAS.cHa

(Hermann-Luibl et al., 2014)

locomotor rhythm defective, with lark^UAS.Tag:HA

(Schroeder et al., 2003)

locomotor rhythm defective, with MagR^KK109272

(Mandilaras and Missirlis, 2012)

locomotor rhythm defective, with mir-279^NE95-11-24

(Luo and Sehgal, 2012)

locomotor rhythm defective, with mir-279^UAS.L

(Luo and Sehgal, 2012)

locomotor rhythm defective, with mir-279^UAS.S

(Luo and Sehgal, 2012)

locomotor rhythm defective, with mir-ban^EP3622

(Kadener et al., 2009)

locomotor rhythm defective, with mts^dn181.UAS

(Sathyanarayanan et al., 2004)

locomotor rhythm defective, with mts^UAS.cHa

(Sathyanarayanan et al., 2004)

locomotor rhythm defective, with mub^KK108209

(Mandilaras and Missirlis, 2012)

locomotor rhythm defective, with na^UAS.cLa

(Lear et al., 2005)

locomotor rhythm defective, with Nfs1^KK101134

(Mandilaras and Missirlis, 2012)

locomotor rhythm defective, with nocte^dsRNA.1.UAS

(Sehadova et al., 2009)

locomotor rhythm defective, with per^dsRNA.Ct.UAS

(Martinek and Young, 2000)

locomotor rhythm defective, with per^{dsRNA.PAS.UAS}

(Ng et al., 2011, Martinek and Young, 2000)

locomotor rhythm defective, with per^UAS.cKa

(Kaneko et al., 2000)

locomotor rhythm defective, with per^UAS.cYa

(Yang and Sehgal, 2001)

locomotor rhythm defective, with qsm^dsRNA.UAS

(Chen et al., 2011)

locomotor rhythm defective, with qsm^GD4817

(Chen et al., 2011)

locomotor rhythm defective, with Scer\GAL80^cry.PS, Shaw^{RA.UAS.Tag:FLAG}

(Hodge and Stanewsky, 2008)

locomotor rhythm defective, with Scer\GAL80^Pdf.PS, cry^{dsRNA.UAS.cPa}

(Picot et al., 2007)

locomotor rhythm defective, with Scer\GAL80^Pdf.PS, per^UAS.cKa

(Stoleru et al., 2007)

locomotor rhythm defective, with Scer\GAL80^Pdf.PS, per^UAS.cYa

(Stoleru et al., 2007)

locomotor rhythm defective, with Scer\GAL80^Pdf.PS, sgg^EP1576

(Stoleru et al., 2007)

locomotor rhythm defective, with Scer\GAL80^Pdf.PS, Shaw^{RA.UAS.Tag:FLAG}

(Hodge and Stanewsky, 2008)

locomotor rhythm defective, with Scer\GAL80^Pdf.PS, tim^UAS.cYa

(Stoleru et al., 2007)

locomotor rhythm defective, with Scer\GAL80^ts.αTub84B, Usp8^DN.UAS

(Luo et al., 2012)

locomotor rhythm defective, with Scer\GAL80^ts.αTub84B, Usp8^dsRNA.2.UAS

(Luo et al., 2012)

locomotor rhythm defective, with sgg^EP1576

(Stoleru et al., 2007, Wülbeck et al., 2005)

locomotor rhythm defective, with sgg^UAS.cBa

(Martinek et al., 2001)

locomotor rhythm defective, with Shaw^{RA.UAS.Tag:FLAG}

(Hodge and Stanewsky, 2008)

locomotor rhythm defective, with slmb^{UAS.ΔFbox.Tag:MYC}

(Ko et al., 2002)

locomotor rhythm defective, with spag^{dsRNA.UAS.cUa}

(Means et al., 2015)

locomotor rhythm defective, with tim^UAS.cYa

(Yang and Sehgal, 2001)

locomotor rhythm defective, with Tsf3^KK109853

(Mandilaras and Missirlis, 2012)

locomotor rhythm defective, with upd1^NIG.5993R

(Luo and Sehgal, 2012)

locomotor rhythm defective, with upd1^UAS.cUa

(Luo and Sehgal, 2012)

locomotor rhythm defective, with wdb^EP3559

(Sathyanarayanan et al., 2004)

locomotor rhythm defective, with Xlae\csnk1d^D132N.UAS

(Fan et al., 2009)

locomotor rhythm defective, with Xlae\csnk1d^S.UAS

(Fan et al., 2009)

locomotor rhythm defective, with Xlae\csnk1d^Tau.UAS

(Fan et al., 2009)

locomotor rhythm defective, with Xlae\csnk1d^WT.UAS

(Fan et al., 2009)

locomotor rhythm defective | adult stage, with Hsap\APP^{T12.Aβ42.UAS.Tag:SS(nec)}

(Chen et al., 2014)

locomotor rhythm defective | adult stage, with Hsap\APP^{T12.Aβ42.UAS.Tag:SS(nec)}, Scer\GAL80^Pdf.PS

(Chen et al., 2014)

locomotor rhythm defective | adult stage, with jet^JF01506

(Lamba et al., 2014)

locomotor rhythm defective | adult stage, with Lsm12a^HMS01143

(Lee et al., 2017)

locomotor rhythm defective | adult stage, with Lsm12a^KK109445

(Lee et al., 2017)

locomotor rhythm defective | adult stage, with me31B^HM05052

(Lee et al., 2017)

locomotor rhythm defective | adult stage, with me31B^NIG.4916R

(Lee et al., 2017)

locomotor rhythm defective | adult stage, with mir-276a^UAS.pLUC

(Chen and Rosbash, 2016)

locomotor rhythm defective | adult stage, with pn^HMC06185

(Chen et al., 2019)

locomotor rhythm defective | adult stage, with Scer\GAL80^Pdf.PS, pn^HMC06185

(Chen et al., 2019)

locomotor rhythm defective | adult stage, with Scer\GAL80^Pdf.PS, TFAM^JF02307

(Chen et al., 2019)

locomotor rhythm defective | adult stage, with Scer\GAL80^Pdf.PS, TFAM^UAS.cCa

(Chen et al., 2019)

locomotor rhythm defective | adult stage, with Srrm1^GL00538, Srrm1^KK108396

(Beckwith et al., 2017)

locomotor rhythm defective | adult stage, with Srrm1^KK108396

(Beckwith et al., 2017)

locomotor rhythm defective | adult stage, with TFAM^JF02307

(Chen et al., 2019)

locomotor rhythm defective | adult stage, with TFAM^UAS.cCa

(Chen et al., 2019)

locomotor rhythm defective | adult stage, with Xvas\XhoI^{UASp.Tag:Mito(kdn),Tag:MYC}

(Chen et al., 2019)

locomotor rhythm defective | adult stage | adult stage, with Pink1^dsRNA.UAS

(Julienne et al., 2017)

locomotor rhythm defective | female, with fbl^GD10556

(Pandey et al., 2013)

locomotor rhythm defective | female, with fbl^KK109160

(Pandey et al., 2013)

mating defective, with Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}

(Kadener et al., 2006)

neuroanatomy defective | adult stage, with dom^HMC04451

(Liu et al., 2019)

neuroanatomy defective | adult stage, with dom^JF01502

(Liu et al., 2019)

neuroanatomy defective | adult stage, with Hsap\APP^{T12.Aβ42.UAS.Tag:SS(nec)}, Scer\GAL80^repo.PL

(Chen et al., 2014)

neurophysiology defective | adult stage, with qsm^GD4817

(Buhl et al., 2016)

oxidative stress response defective, with fbl^GD10556

(Pandey et al., 2013)

partially lethal, with na^E.UAS

(Lear et al., 2005)

phototaxis defective, with Bmul\αBgtx^UAS.cKa

(Keene et al., 2011)

phototaxis defective, with Hsap\KCNJ2^UAS.EGFP

(Keene et al., 2011)

phototaxis defective, with Hsap\KCNJ2^UAS.EGFP, Scer\GAL80^cry.PS

(Keene et al., 2011)

phototaxis defective, with Hsap\KCNJ2^UAS.EGFP, Scer\GAL80^Pdf.PS

(Keene et al., 2011)

short lived, with fbl^GD10556

(Pandey et al., 2013)

short lived, with Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}

(Kadener et al., 2006)

short lived, with Scer\GAL80^cry.PS, Shaw^{RA.UAS.Tag:FLAG}

(Hodge and Stanewsky, 2008)

short lived, with Shaw^{RA.UAS.Tag:FLAG}

(Hodge and Stanewsky, 2008)

short lived | conditional, with mir-210^UAS.cUa

(Niu et al., 2019)

short lived | conditional, with Scer\GAL80^Pdf.PS, mir-210^UAS.cUa

(Niu et al., 2019)

some die during embryonic stage, with hid^UAS.cZa

(Stoleru et al., 2004)

temperature response defective | adult stage, with Dh31-R^GD3782

(Goda et al., 2018)

temperature response defective | adult stage, with Dh31-R^NIG.17043R

(Goda et al., 2018)

viable, with dco^{K38R.UAS.Tag:MYC}

(Muskus et al., 2007)

viable, with lark^UAS.Tag:HA

(Schroeder et al., 2003)

viable, with Xlae\csnk1d^WT.UAS

(Fan et al., 2009)

visual behavior defective, with fbl^GD10556

(Pandey et al., 2013)

Phenotype Manifest In

adult head, with Xvas\XhoI^{UASp.Tag:Mito(kdn),Tag:MYC}

(Chen et al., 2019)

head, with dco^{K38R.UAS.Tag:MYC}

(Means et al., 2015)

head, with spag^{dsRNA.UAS.cUa}

(Means et al., 2015)

larval s-LNv neuron, with dom^JF01502

(Liu et al., 2019)

l-LNv neuron, with Hsap\APP^{T12.Aβ42.UAS.Tag:SS(nec)}, Scer\GAL80^repo.PL

(Chen et al., 2014)

l-LNv neuron | adult stage, with dom^HMC04451

(Liu et al., 2019)

l-LNv neuron | adult stage, with dom^JF01502

(Liu et al., 2019)

l-LNv neuron | adult stage, with qsm^GD4817

(Buhl et al., 2016)

LNv neuron, with Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}

(Kadener et al., 2006)

mitochondrion | adult stage, with Xvas\XhoI^{UASp.Tag:Mito(kdn),Tag:MYC}

(Chen et al., 2019)

pupal s-LNv neuron, with dom^JF01502

(Liu et al., 2019)

s-LNv neuron | adult stage, with dom^HMC04451

(Liu et al., 2019)

s-LNv neuron | adult stage, with dom^JF01502

(Liu et al., 2019)

s-LNv Pdf neuron, with Hsap\APP^{T12.Aβ42.UAS.Tag:SS(nec)}, Scer\GAL80^repo.PL

(Chen et al., 2014)

Detailed Description

Statement

Reference

Blocking clock function (using cyc^{Δ.UAS.Tag:MYC} or tim^UAS.cUa) of Scer\GAL4^tim.PE neurons significantly reduces the circadian rhythmicity of adult emergence after transfer to constant darkness, compared to controls; there is also a reduction when Scer\GAL80^phm.1.2 is present to restrict expression to a smaller subset of Scer\GAL4^tim.PE neurons, but this is not significant for tim^UAS.cUa.

Slowing down clock function (using dco^{L.UAS.Tag:MYC}) of Scer\GAL4^tim.PE neurons significantly slows down the periodicity of adult emergence after transfer to constant darkness, compared to controls; this also occurs when Scer\GAL80^phm.1.2 is present to restrict expression to a smaller subset of Scer\GAL4^tim.PE neurons. Speeding up clock function (using dco^{S.UAS.Tag:MYC}) of Scer\GAL4^tim.PE neurons significantly speeds up the periodicity of adult emergence after transfer to constant darkness, compared to controls; this also occurs, to a lesser extent, when Scer\GAL80^phm.1.2 is present to restrict expression to a smaller subset of Scer\GAL4^tim.PE neurons.

(Selcho et al., 2017)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Bdbt^KK102995, Scer\GAL4^tim.PE has locomotor rhythm defective phenotype, enhanceable by dco^{K38R.UAS.Tag:MYC}, Scer\GAL4^tim.PE

(Fan et al., 2013)

Suppressed by

Statement

Reference

Scer\GAL4^tim.PE, qsm^GD4817 has neurophysiology defective | adult stage phenotype, suppressible | partially by NKCC^NIG.2509R, Scer\GAL4^tim.PE

(Buhl et al., 2016)

Scer\GAL4^tim.PE, qsm^GD4817 has neurophysiology defective | adult stage phenotype, suppressible by Shaw^{RA.UAS.Tag:FLAG}/Scer\GAL4^tim.PE

(Buhl et al., 2016)

Bdbt^KK102995, Scer\GAL4^tim.PE has locomotor rhythm defective phenotype, suppressible by dco^{WT.UAS.Tag:MYC}, Scer\GAL4^tim.PE

(Fan et al., 2013)

Dcr-2^UAS.cDa, Scer\GAL4^tim.PE, gw^KK101472 has locomotor rhythm defective phenotype, suppressible | partially by Pdf^{UAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1)}, Scer\GAL4^tim.PE

(Zhang and Emery, 2013)

Dcr-2^UAS.cDa, Scer\GAL4^tim.PE, gw^HMS00105 has locomotor rhythm defective phenotype, suppressible | partially by Pdf^{UAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1)}, Scer\GAL4^tim.PE

(Zhang and Emery, 2013)

Dcr-2^UAS.cDa, Scer\GAL4^tim.PE, gw^HMS00105 has locomotor rhythm defective phenotype, suppressible | partially by dnc¹

(Zhang and Emery, 2013)

Atx2^KK100423, Scer\GAL4^tim.PE has circadian behavior defective phenotype, suppressible by per^UAS.cYa, Scer\GAL4^tim.PE

(Zhang et al., 2013)

Scer\GAL4^tim.PE, sgg^EP1576 has locomotor rhythm defective phenotype, suppressible | partially by cry^b

(Stoleru et al., 2007)

5-HT1B^dsRNA.UAS, 5-HT1B^UAS.cYa, Scer\GAL4^tim.PE has circadian rhythm defective phenotype, suppressible by cry^b, Scer\GAL4^tim.PE

(Yuan et al., 2005)

Scer\GAL4^tim.PE, cry^UAS.cDa, cry^b has circadian rhythm defective phenotype, suppressible by 5-HT1B^dsRNA.UAS, Scer\GAL4^tim.PE

(Yuan et al., 2005)

Scer\GAL4^tim.PE, sgg^UAS.cBa has circadian rhythm defective phenotype, suppressible | partially by 5-HT1B^UAS.cYa, Scer\GAL4^tim.PE

(Yuan et al., 2005)

NOT suppressed by

Statement

Reference

Dcr-2^UAS.cDa, Scer\GAL4^tim.PE, gw^KK101472 has locomotor rhythm defective phenotype, non-suppressible by Pdf^{UAS.SCR.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1)}, Scer\GAL4^tim.PE

(Zhang and Emery, 2013)

Enhancer of

Statement

Reference

dco^{K38R.UAS.Tag:MYC}, Scer\GAL4^tim.PE is an enhancer of locomotor rhythm defective phenotype of Bdbt^KK102995, Scer\GAL4^tim.PE

(Fan et al., 2013)

per^UAS.cBa, Scer\GAL4^tim.PE, per⁰¹, per[+] is an enhancer of circadian rhythm defective phenotype of cwo^PB9

(Richier et al., 2008)

NOT Enhancer of

Statement

Reference

Atx2^KK100423/Scer\GAL4^tim.PE is a non-enhancer of circadian behavior defective phenotype of tyf^Δ11

(Zhang et al., 2013)

Suppressor of

Statement

Reference

Scer\GAL4^tim.PE/Rh7^UAS.cNa is a suppressor | partially of circadian rhythm defective | adult stage phenotype of Rh7¹, cry^b

(Ni et al., 2017)

NKCC^NIG.2509R, Scer\GAL4^tim.PE is a suppressor | partially of neurophysiology defective | adult stage phenotype of Scer\GAL4^tim.PE, qsm^GD4817

(Buhl et al., 2016)

Shaw^{RA.UAS.Tag:FLAG}/Scer\GAL4^tim.PE is a suppressor of neurophysiology defective | adult stage phenotype of Scer\GAL4^tim.PE, qsm^GD4817

(Buhl et al., 2016)

dco^{WT.UAS.Tag:MYC}, Scer\GAL4^tim.PE is a suppressor of locomotor rhythm defective phenotype of Bdbt^KK102995, Scer\GAL4^tim.PE

(Fan et al., 2013)

Pdf^{UAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1)}, Scer\GAL4^tim.PE is a suppressor | partially of locomotor rhythm defective phenotype of Dcr-2^UAS.cDa, Scer\GAL4^tim.PE, gw^KK101472

(Zhang and Emery, 2013)

Pdf^{UAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1)}, Scer\GAL4^tim.PE is a suppressor | partially of locomotor rhythm defective phenotype of Dcr-2^UAS.cDa, Scer\GAL4^tim.PE, gw^HMS00105

(Zhang and Emery, 2013)

per^UAS.cYa, Scer\GAL4^tim.PE is a suppressor of circadian behavior defective phenotype of Atx2^KK100423, Scer\GAL4^tim.PE

(Zhang et al., 2013)

Scer\GAL4^tim.PE/Dple\cry1^UAS.Tag:MYC is a suppressor of behavior defective phenotype of cry^b

(Gegear et al., 2010)

Scer\GAL4^tim.PE/Dple\cry2^UAS.Tag:MYC is a suppressor of behavior defective phenotype of cry^b

(Gegear et al., 2010)

Dple\cry1^W328F.UAS/Scer\GAL4^tim.PE is a suppressor of behavior defective phenotype of cry^b

(Gegear et al., 2010)

cyc^VP16.UAS/Scer\GAL4^tim.PE is a suppressor of locomotor rhythm defective phenotype of Clk^ar

(Kadener et al., 2008)

Scer\GAL4^tim.PE/Dple\cry1^UAS.cZa is a suppressor | partially of circadian behavior defective phenotype of cry^b

(Zhu et al., 2008)

cry^b, Scer\GAL4^tim.PE is a suppressor of circadian rhythm defective phenotype of 5-HT1B^dsRNA.UAS, 5-HT1B^UAS.cYa, Scer\GAL4^tim.PE

(Yuan et al., 2005)

5-HT1B^dsRNA.UAS, Scer\GAL4^tim.PE is a suppressor of circadian rhythm defective phenotype of Scer\GAL4^tim.PE, cry^UAS.cDa, cry^b

(Yuan et al., 2005)

5-HT1B^UAS.cYa, Scer\GAL4^tim.PE is a suppressor | partially of circadian rhythm defective phenotype of Scer\GAL4^tim.PE, sgg^UAS.cBa

(Yuan et al., 2005)

NOT Suppressor of

Statement

Reference

Scer\GAL4^tim.PE/na^UAS.cLa is a non-suppressor of circadian behavior defective phenotype of unc80^x42

(Lear et al., 2013)

Scer\GAL4^tim.PE/unc79^UAS.Tag:MYC is a non-suppressor of circadian behavior defective phenotype of unc80^x42

(Lear et al., 2013)

Scer\GAL4^tim.PE/na^UAS.cLa is a non-suppressor of circadian behavior defective phenotype of unc79^x25

(Lear et al., 2013)

Scer\GAL4^tim.PE/unc80^UAS.Tag:HA is a non-suppressor of circadian behavior defective phenotype of unc79^x25

(Lear et al., 2013)

Scer\GAL4^tim.PE, unc80^UAS.Tag:HA, na^UAS.cLa is a non-suppressor of circadian behavior defective phenotype of unc79^x25

(Lear et al., 2013)

Pdf^{UAS.SCR.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1)}, Scer\GAL4^tim.PE is a non-suppressor of locomotor rhythm defective phenotype of Dcr-2^UAS.cDa, Scer\GAL4^tim.PE, gw^KK101472

(Zhang and Emery, 2013)

Atx2^KK100423/Scer\GAL4^tim.PE is a non-suppressor of circadian behavior defective phenotype of tyf^Δ11

(Zhang et al., 2013)

Scer\GAL4^tim.PE/Dple\cry2^W345F.UAS is a non-suppressor of behavior defective phenotype of cry^b

(Gegear et al., 2010)

Scer\GAL4^tim.PE/Dple\cry2^UAS.cZa is a non-suppressor of circadian behavior defective phenotype of cry^b

(Zhu et al., 2008)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^tim.PE, qsm^GD4817 has l-LNv neuron | adult stage phenotype, suppressible | partially by NKCC^NIG.2509R, Scer\GAL4^tim.PE

(Buhl et al., 2016)

Scer\GAL4^tim.PE, qsm^GD4817 has l-LNv neuron | adult stage phenotype, suppressible by Shaw^{RA.UAS.Tag:FLAG}/Scer\GAL4^tim.PE

(Buhl et al., 2016)

Suppressor of

Statement

Reference

NKCC^NIG.2509R, Scer\GAL4^tim.PE is a suppressor | partially of l-LNv neuron | adult stage phenotype of Scer\GAL4^tim.PE, qsm^GD4817

(Buhl et al., 2016)

Shaw^{RA.UAS.Tag:FLAG}/Scer\GAL4^tim.PE is a suppressor of l-LNv neuron | adult stage phenotype of Scer\GAL4^tim.PE, qsm^GD4817

(Buhl et al., 2016)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^tim.PE/dom^UAS.A rescues dom^HMC04451

(Liu et al., 2019)

dom^UAS.B/Scer\GAL4^tim.PE rescues dom^HMC04203

(Liu et al., 2019)

dom^UAS.B/Scer\GAL4^tim.PE rescues dom^HMC04451

(Liu et al., 2019)

Scer\GAL4^tim.PE/jet^UAS.cKa rescues jet^set

(Lamba et al., 2014)

Scer\GAL4^tim.PE, dco^EY02910 rescues dco^EY02910

(Zheng et al., 2014)

Scer\GAL4^tim.PE/shn^HMS01167 rescues shn⁷⁵⁶

(Beckwith et al., 2013)

Scer\GAL4^tim.PE/Bdbt^UAS.Tag:FLAG rescues Bdbt^KK102995

(Fan et al., 2013)

Scer\GAL4^tim.PE, unc79^f01615 rescues unc79^x25/unc79^f01615

(Lear et al., 2013)

Scer\GAL4^tim.PE/unc80^UAS.Tag:HA rescues unc80^x42

(Lear et al., 2013)

Scer\GAL4^tim.PE/TrpA1^UAS.(B).cKa rescues TrpA1¹

(Lee and Montell, 2013)

Scer\GAL4^tim.PE/TrpA1^UAS.B.Kwon rescues TrpA1¹

(Lee and Montell, 2013)

gw^shRNAres.UAS/Scer\GAL4^tim.PE rescues gw^HMS00105

(Zhang and Emery, 2013)

Scer\GAL4^tim.PE/per^UAS.cYa rescues per⁰¹

(Kaneko et al., 2012)

Scer\GAL4^tim.PE, ctrip^NIG.17735R, ctrip^GS11430 rescues ctrip^NIG.14656R

(Lamaze et al., 2011)

Scer\GAL4^tim.PE/cry^UAS.Tag:MYC rescues cry^b

(Gegear et al., 2010)

Scer\GAL4^tim.PE/cry^W342F.UAS rescues cry^b

(Gegear et al., 2010)

robo1^UAS.Tag:MYC/Scer\GAL4^tim.PE rescues robo1^BG01092

(Berni et al., 2008)

Scer\GAL4^tim.PE/cwo^UAS.cKa rescues cwo^e04207/cwo^f05073

(Kadener et al., 2007)

cry^UAS.cEa/Scer\GAL4^tim.PE rescues cry^b

(Picot et al., 2007)

cry^UAS.cEa, Scer\GAL4^tim.PE, Scer\GAL80^Pdf.PS rescues cry^b

(Picot et al., 2007)

Scer\GAL4^tim.PE, cry^UAS.Tag:MYC, Scer\GAL80^Pdf.PS rescues cry^b

(Stoleru et al., 2007)

Scer\GAL4^tim.PE/cry^UAS.Tag:MYC rescues cry^b

(Stoleru et al., 2007)

Scer\GAL4^tim.PE/na^UAS.cLa rescues na^har

(Lear et al., 2005)

Scer\GAL4^tim.PE/cry^UAS.Tag:MYC rescues cry^b

(Busza et al., 2004)

Scer\GAL4^tim.PE/cry^UAS.cDa rescues cry^b

(Dissel et al., 2004)

Scer\GAL4^tim.PE, Phm^UAS.cTA, Scer\GAL4^Kdm2-36Y rescues Phm^k07623/Phm^P(29)

(Taghert et al., 2001)

Scer\GAL4^tim.PE, Scer\GAL4^dimm-929, Phm^UAS.cTA rescues Phm^k07623/Phm^P(29)

(Taghert et al., 2001)

cry^UAS.cEa/Scer\GAL4^tim.PE rescues cry^b

(Emery et al., 2000)

cry^UAS.cEa/Scer\GAL4^tim.PE rescues cry^b

(Emery et al., 2000)

Scer\GAL4^tim.PE/to^UAS.cSBa rescues to¹

(Sarov-Blat et al., 2000)

Partially rescues

Scer\GAL4^tim.PE/Dh31-R^UAS.cGa partially rescues Dh31-R^NIG.17043R

(Goda et al., 2018)

Scer\GAL4^tim.PE/unc79^UAS.Tag:MYC partially rescues unc79^x25

(Lear et al., 2013)

Scer\GAL4^tim.PE/Pdfr^UAS.cMa partially rescues Pdfr³³⁶⁹

(Im and Taghert, 2010)

Scer\GAL4^tim.PE/S6kII^UAS.cRa partially rescues S6kII^ign-Δ58-1

(Akten et al., 2009)

per^UAS.cBa/Scer\GAL4^tim.PE partially rescues per⁰¹

(Rieger et al., 2009)

Scer\GAL4^tim.PE/jet^UAS.cKa partially rescues jet^c

(Koh et al., 2006)

Scer\GAL4^tim.PE/jet^UAS.cKa partially rescues jet^r

(Koh et al., 2006)

Fails to rescue

Scer\GAL4^tim.PE/dom^UAS.A fails to rescue dom^HMC04203

(Liu et al., 2019)

Scer\GAL4^tim.PE/gw^{AA.shRNAres.UAS} fails to rescue gw^HMS00105

(Zhang and Emery, 2013)

dysc^UAS.long/Scer\GAL4^tim.PE fails to rescue dysc^s168/dysc^c03838

(Jepson et al., 2012)

Scer\GAL4^tim.PE, inc^f00285 fails to rescue inc^f00285

(Stavropoulos and Young, 2011)

Scer\GAL4^tim.PE/na^E.UAS fails to rescue na^har

(Lear et al., 2005)

Scer\GAL4^tim.PE/cry^Δ5'.UAS.cDa fails to rescue cry^b

(Dissel et al., 2004)

Scer\GAL4^tim.PE/Phm^UAS.cTA fails to rescue Phm^k07623/Phm^P(29)

(Taghert et al., 2001)

Scer\GAL4^tim.PE/Nf1^UAS.cdNa fails to rescue Nf1^P1

(Williams et al., 2001)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

7126

y¹ w^*; P{GAL4-tim.E}62

80976

y¹ w^*; P{GAL4-tim.E}27/CyO; P{EPgy2}dco^EY02910/TM3, Sb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

GAL4^tim.PE

Scer\GAL4^tim.PE

TG²⁷

(Kumar et al., 2014)

Name Synonyms

timeless promoter construct of Emery

(Emery et al., 1998)

Secondary FlyBase IDs

References (144)

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