Comment: Assayed at ZT23
Comment: Authors state tim-gal4 is known to express in all clock neurons.
Comment: medium expression
Comment: faint expression
Drives expression in pacemaker neurons at all developmental stages.
ScerGAL4tim.PE transcript is expressed in the embryonic brain at stage 16 in 100 cells. These cells co-express tim protein.
The larval Pdf negative s-LNv neuron is concluded to have the same projection pattern as the larval PDF-positive s-LNv neurons.
Expression of ScerGAL4tim.PE is seen in cells near sensilla on the head capsule, thorax and abdomen of the adult. Expression of ScerGAL4tim.PE in seen within the abdominal portion of the adult midgut. Expression in the mouth is restricted to the posterior region.
lethal, with Usp8DN.UAS
lethal, with Usp8RNAi.2.UAS
Blocking clock function (using cycΔ.UAS.Tag:MYC or timUAS.cUa) of Scer\GAL4tim.PE neurons significantly reduces the circadian rhythmicity of adult emergence after transfer to constant darkness, compared to controls; there is also a reduction when Scer\GAL80phm.1.2 is present to restrict expression to a smaller subset of Scer\GAL4tim.PE neurons, but this is not significant for timUAS.cUa.
Slowing down clock function (using dcoL.UAS.Tag:MYC) of Scer\GAL4tim.PE neurons significantly slows down the periodicity of adult emergence after transfer to constant darkness, compared to controls; this also occurs when Scer\GAL80phm.1.2 is present to restrict expression to a smaller subset of Scer\GAL4tim.PE neurons. Speeding up clock function (using dcoS.UAS.Tag:MYC) of Scer\GAL4tim.PE neurons significantly speeds up the periodicity of adult emergence after transfer to constant darkness, compared to controls; this also occurs, to a lesser extent, when Scer\GAL80phm.1.2 is present to restrict expression to a smaller subset of Scer\GAL4tim.PE neurons.
BdbtKK102995, Scer\GAL4tim.PE has abnormal locomotor rhythm phenotype, enhanceable by dcoK38R.UAS.Tag:MYC, Scer\GAL4tim.PE
Scer\GAL4tim.PE, dcoK38R.UAS.Tag:MYC has decreased sleep | adult stage phenotype, suppressible by per01
Scer\GAL4tim.PE, qsmGD4817 has abnormal neurophysiology | adult stage phenotype, suppressible | partially by NKCCNIG.2509R, Scer\GAL4tim.PE
Scer\GAL4tim.PE, qsmGD4817 has abnormal neurophysiology | adult stage phenotype, suppressible by ShawRA.UAS.Tag:FLAG/Scer\GAL4tim.PE
BdbtKK102995, Scer\GAL4tim.PE has abnormal locomotor rhythm phenotype, suppressible by dcoWT.UAS.Tag:MYC, Scer\GAL4tim.PE
Dcr-2UAS.cDa, Scer\GAL4tim.PE, gwKK101472 has abnormal locomotor rhythm phenotype, suppressible | partially by PdfUAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1), Scer\GAL4tim.PE
Dcr-2UAS.cDa, Scer\GAL4tim.PE, gwHMS00105 has abnormal locomotor rhythm phenotype, suppressible | partially by PdfUAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1), Scer\GAL4tim.PE
Dcr-2UAS.cDa, Scer\GAL4tim.PE, gwHMS00105 has abnormal locomotor rhythm phenotype, suppressible | partially by Pde4dnc-1
Atx2KK100423, Scer\GAL4tim.PE has abnormal circadian behavior phenotype, suppressible by perUAS.cYa, Scer\GAL4tim.PE
Scer\GAL4tim.PE, sggEP1576 has abnormal locomotor rhythm phenotype, suppressible | partially by cryb
5-HT1BRNAi.UAS, 5-HT1BUAS.cYa, Scer\GAL4tim.PE has abnormal circadian rhythm phenotype, suppressible by cryb, Scer\GAL4tim.PE
Scer\GAL4tim.PE, cryUAS.cDa, cryb has abnormal circadian rhythm phenotype, suppressible by 5-HT1BRNAi.UAS, Scer\GAL4tim.PE
Scer\GAL4tim.PE, sggUAS.cBa has abnormal circadian rhythm phenotype, suppressible | partially by 5-HT1BUAS.cYa, Scer\GAL4tim.PE
Dcr-2UAS.cDa, Scer\GAL4tim.PE, gwKK101472 has abnormal locomotor rhythm phenotype, non-suppressible by PdfUAS.SCR.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1), Scer\GAL4tim.PE
dcoK38R.UAS.Tag:MYC, Scer\GAL4tim.PE is an enhancer of abnormal locomotor rhythm phenotype of BdbtKK102995, Scer\GAL4tim.PE
perUAS.cBa, Scer\GAL4tim.PE, per01, per[+] is an enhancer of abnormal circadian rhythm phenotype of cwoPB9
Atx2KK100423/Scer\GAL4tim.PE is a non-enhancer of abnormal circadian behavior phenotype of tyfΔ11
Scer\GAL4tim.PE/CipcKK104160 is a suppressor | partially of abnormal circadian rhythm | adult stage phenotype of cwof05073
Scer\GAL4tim.PE/Rh7UAS.cNa is a suppressor | partially of abnormal circadian rhythm | adult stage phenotype of Rh71, cryb
NKCCNIG.2509R, Scer\GAL4tim.PE is a suppressor | partially of abnormal neurophysiology | adult stage phenotype of Scer\GAL4tim.PE, qsmGD4817
ShawRA.UAS.Tag:FLAG/Scer\GAL4tim.PE is a suppressor of abnormal neurophysiology | adult stage phenotype of Scer\GAL4tim.PE, qsmGD4817
dcoWT.UAS.Tag:MYC, Scer\GAL4tim.PE is a suppressor of abnormal locomotor rhythm phenotype of BdbtKK102995, Scer\GAL4tim.PE
PdfUAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1), Scer\GAL4tim.PE is a suppressor | partially of abnormal locomotor rhythm phenotype of Dcr-2UAS.cDa, Scer\GAL4tim.PE, gwKK101472
PdfUAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1), Scer\GAL4tim.PE is a suppressor | partially of abnormal locomotor rhythm phenotype of Dcr-2UAS.cDa, Scer\GAL4tim.PE, gwHMS00105
perUAS.cYa, Scer\GAL4tim.PE is a suppressor of abnormal circadian behavior phenotype of Atx2KK100423, Scer\GAL4tim.PE
Scer\GAL4tim.PE/Dple\cry1UAS.Tag:MYC is a suppressor of abnormal behavior phenotype of cryb
Scer\GAL4tim.PE/Dple\cry2UAS.Tag:MYC is a suppressor of abnormal behavior phenotype of cryb
Dple\cry1W328F.UAS/Scer\GAL4tim.PE is a suppressor of abnormal behavior phenotype of cryb
cycVP16.UAS/Scer\GAL4tim.PE is a suppressor of abnormal locomotor rhythm phenotype of Clkar
Scer\GAL4tim.PE/Dple\cry1UAS.cZa is a suppressor of abnormal circadian behavior phenotype of cryb
cryb, Scer\GAL4tim.PE is a suppressor of abnormal circadian rhythm phenotype of 5-HT1BRNAi.UAS, 5-HT1BUAS.cYa, Scer\GAL4tim.PE
5-HT1BRNAi.UAS, Scer\GAL4tim.PE is a suppressor of abnormal circadian rhythm phenotype of Scer\GAL4tim.PE, cryUAS.cDa, cryb
5-HT1BUAS.cYa, Scer\GAL4tim.PE is a suppressor | partially of abnormal circadian rhythm phenotype of Scer\GAL4tim.PE, sggUAS.cBa
Scer\GAL4tim.PE/naUAS.cLa is a non-suppressor of abnormal circadian behavior phenotype of unc79x25
Scer\GAL4tim.PE/unc80UAS.Tag:HA is a non-suppressor of abnormal circadian behavior phenotype of unc79x25
Scer\GAL4tim.PE, unc80UAS.Tag:HA, naUAS.cLa is a non-suppressor of abnormal circadian behavior phenotype of unc79x25
Scer\GAL4tim.PE/naUAS.cLa is a non-suppressor of abnormal circadian behavior phenotype of unc80x42
Scer\GAL4tim.PE/unc79UAS.Tag:MYC is a non-suppressor of abnormal circadian behavior phenotype of unc80x42
PdfUAS.SCR.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1), Scer\GAL4tim.PE is a non-suppressor of abnormal locomotor rhythm phenotype of Dcr-2UAS.cDa, Scer\GAL4tim.PE, gwKK101472
Atx2KK100423/Scer\GAL4tim.PE is a non-suppressor of abnormal circadian behavior phenotype of tyfΔ11
Scer\GAL4tim.PE/Dple\cry2W345F.UAS is a non-suppressor of abnormal behavior phenotype of cryb
Scer\GAL4tim.PE/Dple\cry2UAS.cZa is a non-suppressor of abnormal circadian behavior phenotype of cryb
Scer\GAL4tim.PE, qsmGD4817 has l-LNv neuron | adult stage phenotype, suppressible | partially by NKCCNIG.2509R, Scer\GAL4tim.PE
Scer\GAL4tim.PE, qsmGD4817 has l-LNv neuron | adult stage phenotype, suppressible by ShawRA.UAS.Tag:FLAG/Scer\GAL4tim.PE
NKCCNIG.2509R, Scer\GAL4tim.PE is a suppressor | partially of l-LNv neuron | adult stage phenotype of Scer\GAL4tim.PE, qsmGD4817
ShawRA.UAS.Tag:FLAG/Scer\GAL4tim.PE is a suppressor of l-LNv neuron | adult stage phenotype of Scer\GAL4tim.PE, qsmGD4817
cryUAS.cEa/Scer\GAL4tim.PE rescues cryb
Scer\GAL4tim.PE/naUAS.cLa rescues nahar
Scer\GAL4tim.PE/cryUAS.cDa rescues cryb
cryUAS.cEa/Scer\GAL4tim.PE rescues cryb
cryUAS.cEa/Scer\GAL4tim.PE rescues cryb
Scer\GAL4tim.PE/Dh31-RUAS.cGa partially rescues Dh31-RNIG.17043R
Scer\GAL4tim.PE/unc79UAS.Tag:MYC partially rescues unc79x25
Scer\GAL4tim.PE/PdfrUAS.cMa partially rescues Pdfr3369
Scer\GAL4tim.PE/S6kIIUAS.cRa partially rescues S6kIIign-Δ58-1
perUAS.cBa/Scer\GAL4tim.PE partially rescues per01
Scer\GAL4tim.PE/jetUAS.cKa partially rescues jetc
Scer\GAL4tim.PE/jetUAS.cKa partially rescues jetr
Scer\GAL4tim.PE/domUAS.A fails to rescue domHMC04203
Scer\GAL4tim.PE/gwAA.UAS.RR fails to rescue gwHMS00105
dyscUAS.long/Scer\GAL4tim.PE fails to rescue dyscs168/dyscc03838
Scer\GAL4tim.PE, incf00285 fails to rescue incf00285
Scer\GAL4tim.PE/naE.UAS fails to rescue nahar
Scer\GAL4tim.PE/cryΔ5'.UAS.cDa fails to rescue cryb
Scer\GAL4tim.PE/PhmUAS.cTA fails to rescue Phmk07623/PhmP(29)
Scer\GAL4tim.PE/Nf1UAS.cdNa fails to rescue Nf1P1