FB2025_01 , released February 20, 2025
Allele: Dmel\wupA18242DL
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General Information
Symbol
Dmel\wupA18242DL
Species
D. melanogaster
Name
FlyBase ID
FBal0095143
Feature type
allele
Associated gene
Dmel\wupA
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Prado et al., 1999)
Progenitor genotype
Cytology
Description

540bp insertion at position 10537, in the intron between exons 7 and 8.

(Prado et al., 1999)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
insertion
X:18,106,824..18,106,825 [-]
Comment:

A 540bp insertion at position 10537 of GB:X58188, in the intron between exons 7 and 8.

(Prado et al., 1999)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The '18242DL' chromosome (in which wupA, l(1)16Fe and l(1)16Fm are inactivated) is dominant lethal.

      (Prado et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      wupA18242DL has lethal | dominant phenotype, suppressible by Dp(1;3)JC153

      (Casas-Tintó and Ferrús, 2021)

      wupA18242DL has lethal | dominant phenotype, suppressible by Dp(1;2)CH322-143G12

      (Casas-Tintó and Ferrús, 2021)
      NOT suppressed by
      Statement
      Reference

      wupA18242DL has lethal | dominant phenotype, non-suppressible by Dp(1;2)CH322-61E2

      (Casas-Tintó and Ferrús, 2021)

      wupA18242DL has lethal | dominant phenotype, non-suppressible by Dp(1;3)CH322-4P16

      (Casas-Tintó and Ferrús, 2021)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Separable from: l(1)16Fe18242DL. Separable from: l(1)16Fm18242DL. Mutation in the 'dominant lethal' domain of 16F which inactivates the wupA, l(1)16Fe and l(1)16Fm genes.

      (Prado et al., 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      18242DL
      (Prado et al., 1999)
      l(1)18242DL
      (Casas-Tintó and Ferrús, 2021)
      wupA18242DL
      Name Synonyms
      Secondary FlyBase IDs
        References (2)