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General Information
Symbol
Dmel\gig193
Species
D. melanogaster
Name
FlyBase ID
FBal0095407
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Tsc2193
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
complex substitution
Comment:

A 166 bp deletion and 10bp insertion that causes an in frame deletion of 56 amino acids from amino acid 472 to 527 and the addition of four amino acids. Position of mutation on reference sequence inferred by FlyBase curator based on author statement.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

166 bp deletion and 10bp insertion that causes an in frame deletion of 56 amino acids from amino acid 472 to 527 and the addition of four amino acids.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference

gig193/gig109 has lethal | larval stage phenotype, suppressible | partially by TorE161K/Tor[+]

gig193/gig109 has lethal | larval stage phenotype, suppressible | partially by Tor[+]/TorΔP

Tor+t9.4, gig193/gig109 has lethal | larval stage phenotype, suppressible | partially by Tor2L1/Tor[+]

gig193/gig109 has lethal | larval stage phenotype, suppressible | partially by Tor2L1/Tor[+]

gig193/gig109 has lethal | larval stage phenotype, suppressible | partially by Tor[+]/TorA948V

gig193/gig109 has lethal | larval stage phenotype, suppressible | partially by TorV2148D/Tor[+]

gig193/gig109 has lethal | larval stage phenotype, suppressible | partially by Tor[+]/TorW1251R

NOT suppressed by
Statement
Reference

Tor+t9.4, gig193/gig109 has lethal | larval stage phenotype, non-suppressible by Tor[+]/TorΔP

gig193/gig109 has lethal | larval stage phenotype, non-suppressible by Tor[+]/TorEP2353/Scer\GAL4[-]

gig193/gig109 has lethal phenotype, non-suppressible by Tor[+]/TorG2256D

gig193/gig109 has lethal | larval stage phenotype, non-suppressible by Tor[+]/TorG2256D

gig193/gig109 has lethal | larval stage phenotype, non-suppressible by Tor[+]/Tork17004

gig193/gig109 has lethal | larval stage phenotype, non-suppressible | partially by Tor[+]/TorΔP

Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The percentage of gig109/gig193 mutants that survive to adult stages is increased from 0 to around 30% when flies are also TorE161K/+, to around 45% when flies are also TorA948V/+ or TorW1251R/+ and to 60% when they are Tor2L1/+. Around 2% of TorV2148D/+; gig109/gig193 flies survive to adulthood. Around 60% of gig109/gig193; TorΔP/+ flies survive to the pupal, but not the adult stage. However, one copy of the Tor+t9.4 transgene blocks the ability of TorΔP/+ to rescue gig109/gig193 flies to pupal viability. The Tor+t9.4 transgene reduces the amount of Tor2L1/+; gig109/gig193 flies that survive to the pupal stage from around 85% to around 65%.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Selected as: eye morphology mutant in FRT/FLP screen.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (3)