FB2025_01 , released February 20, 2025
Allele: Dmel\Delta03745b
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General Information
Symbol
Dmel\Delta03745b
Species
D. melanogaster
Name
FlyBase ID
FBal0095824
Feature type
allele
Associated gene
Dmel\Delta
Associated Insertion(s)
P{PZ}Delta03745b
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Maixner et al., 1998)
Progenitor genotype
Associated Insertion(s)
P{PZ}Delta03745b
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Delta03745b/tws03745a is a suppressor of lethal phenotype of Ras85DV12.sev, sevS11.Tag:MYC

      (Maixner et al., 1998)
      Other
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The lethality caused by sevS11.T:Hsap\MYC in combination with Ras85DV12.sev is suppressed by the l(3)03745 line. The l(3)03745 line has two P{PZ} insertions: one at 85F12--85F13 producing tws03745a and one at 92A1--92A2 producing Dl03745b. The suppression of the lethality caused by sevS11.T:Hsap\MYC in combination with Ras85DV12.sev by the l(3)03745 line is probably due to the additive effects of the tws03745a and Dl03745b mutations.

      (Maixner et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Separable from: tws03745a.

      (Maixner et al., 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Delta03745b
      Dl03745b
      l(3)03745
      (Maixner et al., 1998)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)