FB2025_01 , released February 20, 2025
Allele: Dmel\Act5CUAS.GFP
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General Information
Symbol
Dmel\Act5CUAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0095890
Feature type
allele
Associated gene
Dmel\Act5C
Associated Insertion(s)
Carried in Construct
P{UAS-Act5C.T:GFP}
Also Known As
UAS-GFP-actin, UAS-actin-GFP, UAS-Actin::GFP, actin-GFP, GFP-actin, Actin::GFP, UAS-GFP::actin, UAS-actinGFP, UAS-Act-GFP, UASActinGFP
Key Links
Transgenic product class
wild_type
(Verkhusha et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Verkhusha et al., 1999)
Mutagen
in vitro construct
(Verkhusha et al., 1999)
Progenitor genotype
Carried in construct
P{UAS-Act5C.T:GFP}
Cytology
Description

Act5C tagged at the N-terminal end with GFP is expressed under the control of UASt regulatory sequences.

(Verkhusha et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Act5C
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  tauopathy
      modeled by Hsap\MAPTV337M.UAS
      (Fulga et al., 2007)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Phenotype Manifest In
      Enhancer of
      NOT Enhancer of
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4Act5C.PI/Act5CUAS.GFP is a non-suppressor of embryonic segment phenotype of Rho1unspecified

      (Magie et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Act5CScer\UAS.T:Avic\GFP under the control of Scer\GAL4Act5C.PI has no effect on the severity of the Rho1unspecified mutant phenotype.

      (Magie et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Act5CScer\UAS.T:Avic\GFP in flies expressing Hsap\MAPTV337M.Scer\UAS in the eye under the control of Scer\GAL4GMR.PF enhances the rough-eye phenotype.

      Expression of Act5CScer\UAS.T:Avic\GFP in animals expressing Hsap\MAPTR406W.Scer\UAS under the control of Scer\GAL4elav.PLu enhances neuronal cell death.

      Expression of Act5CScer\UAS.T:Avic\GFP in animals expressing Hsap\MAPTE14.Scer\UAS in the retina under the control of Scer\GAL4GMR.PF enhances the rough-eye phenotype.

      Expression of Act5CScer\UAS.T:Avic\GFP in animals expressing Hsap\MAPTAP.Scer\UAS in the retina under the control of Scer\GAL4GMR.PF does not enhance the rough-eye phenotype.

      (Fulga et al., 2007)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Act5CScer\UAS.T:Avic\GFP
      Act5CUAS.GFP
      Name Synonyms
      actin
      (Jiang and Crews, 2006)
      actin-GFP
      (Kockel et al., 2001)
      Secondary FlyBase IDs
        References (79)