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General Information
Symbol
Dmel\α-CatUAS.sgGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0095916
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-α-catenin-GFP, α-catenin-GFP, UAS-DαC-GFP, UAS-α-Cat-GFP, UAS-Dα-cat-GFP, UAS-Dα-catenin-GFP, UAS-αCat-GFP, α-Cat-GFP
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UAS regulatory sequences drive expression of full length α-Cat tagged at the carboxyl terminus with sgGFP.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Expression of Scer\GAL4GMR.PF driven α-CatScer\UAS.T:Avic\GFP-sg does not effect patterning of the eye compared to Scer\GAL4GMR.PF alone.
Expression of α-CatScer\UAS.T:Avic\GFP-sg under the control of Scer\GAL4GMR.PF results in low level failure to switch cone-cell contacts.
α-CatScer\UAS.T:Avic\GFP-sg when driven by Scer\GAL4btl.PS produces embryos with normal adherens junction patterns. Almost all (98.9%) dorsal trunk fusions are successful.
No morphological abnormalities are seen in embryos expressing α-CatScer\UAS.T:Avic\GFP-sg under the control of Scer\GAL4en-e16E.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Expression of Scer\GAL4GMR.PF driven α-CatScer\UAS.T:Avic\GFP-sg leads to a mild suppression of the Nfa-g pupal retina phenotypes. Expression of Scer\GAL4GMR.PF driven α-CatScer\UAS.T:Avic\GFP-sg leads to a mild enhancement of some of the rst6 pupal retina patterning phenotypes. Expression of Scer\GAL4GMR.PF driven α-CatScer\UAS.T:Avic\GFP-sg leads to a mild enhancement of the p120ctn308 pupal retina patterning error phenotypes.
Expression of α-CatScer\UAS.T:Avic\GFP-sg strongly enhances the cone cell switching phenotype seen 41-42 hours after pupal formation when pyd3.dsRNA.Scer\UAS is expressed under the control of Scer\GAL4GMR.PF. A greater proportion of ommatidia maintain the immature A/P configuration rather than switching to the E/P configuration as is seen in controls.
shg2/Df(2R)E2 embryos with α-CatScer\UAS.T:Avic\GFP-sg driven by Scer\GAL4btl.PS, show largely disordered tracheal branching. No successful dorsal trunk fusions are seen in these embryos. The addition of shgScer\UAS.cOa to these flies rescues these phenotypes to nearly wild-type. Tracheal patterning is normal, although tracheal branches and connectives in the embryos are less extended than in wild-type.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
α-CatScer\UAS.T:Avic\GFP-sg
α-CatScer\UAS.T:Avic\GFP
α-CatUAS.sgGFP
Name Synonyms
Secondary FlyBase IDs
    References (39)