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General Information
Symbol
Dmel\sqdS
Species
D. melanogaster
Name
FlyBase ID
FBal0096680
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A 15kb genomic fragment containing sqd, in which the alternatively spliced exons have been replaced with the corresponding region of a cDNA encoding the sqdS isoform.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues

sqdS partially rescues sqd1

sqdS partially rescues sqd1

Fails to rescue

sqdS fails to rescue sqd1

Comments

Expression of the sqdB isoform is not sufficient to rescue the sqd1 dorsal-ventral patterning defects, such that the eggs remain unfertilised.

The nurse cell chromosome defect seen in sqd1 homozygotes is partially rescued by 2 copies of sqdS, amd almost completely rescued by sqdS + sqdB or + sqdA.

68.9% of eggs derived from homozygous sqd1 females carrying sqdS are wild type. 98.4% of eggs derived from homozygous sqd1 females carrying both sqdA and sqdS are wild type. Partially rescues the lethality of sqdix50/Df(3R)urd.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
sqdS
Name Synonyms
Secondary FlyBase IDs
    References (4)