FB2025_01 , released February 20, 2025
Allele: Dmel\mgeA1
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General Information
Symbol
Dmel\mgeA1
Species
D. melanogaster
Name
FlyBase ID
FBal0096777
Feature type
allele
Associated gene
Dmel\mge
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Vaskova et al., 2000)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      mgeA1/mgeB10, mgeA1/Df(3L)449 and mgeA1/Df(3L)GN19 animals proceed through embryogenesis and hatch on schedule. However, the larvae do not grow but remain as first instars for 5-9 days (the normal first instar period is 24 hours). No gross morphological defects are seen, but mutant larvae appear to move more slowly than wild type.

      (Vaskova et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Homozygotes are embryonic lethal, presumably due to an unrelated second-site mutation on the chromosome.

      (Vaskova et al., 2000)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      l(3)63FcA1
      (Harrison, 1999.5.12)
      l(3)63Fca1
      (Vaskova et al., 2000)
      mgeA1
      (Kanellopoulos et al., 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)