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General Information
Symbol
Dmel\Trf2G0071
Species
D. melanogaster
Name
FlyBase ID
FBal0096834
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Maps approximately halfway through the Trf2 locus.

Insertion components
P{lacW}Trf2G0071
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The size of large lipid droplets in the fat body of Trf2G0071 homozygous mutant larvae (second, early third as well as wandering third instar larval stage) is significantly increased compared to controls.

Mutants show defects in destruction of the larval salivary glands, having persistant larval salivary glands at the pupal stage.

Homozygous Trf2G0071 are lethal, with majority of lethality occurring during the first instar larval stage. Those surviving to early pupae show defects in head eversion. No embryonic lethality is observed.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
NOT suppressed by
Additional Comments
Genetic Interactions
Statement
Reference

The increased size of fat body lipid droplets characteristic for Trf2G0071 mutant wandering third instar larvae is not significantly altered by expression of CG9527Scer\UAS.T:Zzzz\FLAG or CG4586Scer\UAS.T:Zzzz\FLAG or Taf12LScer\UAS.T:Zzzz\FLAG but is significantly rescued by expression of any of the following: CG2617Scer\UAS.T:Zzzz\FLAG, AANATL2Scer\UAS.T:Zzzz\FLAG, CG9507Scer\UAS.T:Zzzz\FLAG or eIF2BδScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4ppl.PP.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

The increased size of fat body lipid droplets characteristic for Trf2G0071 mutant wandering third instar larvae can be rescued by expression of either Trf2Scer\UAS.s or Trf2Scer\UAS.l under the control of Scer\GAL4ppl.PP in the mutant background (which on its own leads to reduced lipid droplet size).

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Comments
Comments

P{lacW} not verified as causing the lethality.

External Crossreferences and Linkouts ( 1 )
Crossreferences
GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
Synonyms and Secondary IDs (5)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (8)